Book Hotels in Anniston, MO

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Top Anniston hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $108 total per night from Jan 25 to Jan 26
$108 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Good

Reviewed on Jan 14, 2026

Opens in a new windowDrury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue Sikeston MO
$75 nightly
The price is $86 total per night from Jan 25 to Jan 26
$86 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
The staff was very welcoming and helpful. Our room was very clean and comfortable with lots of amenities. The breakfast was delicious with a wide variety of foods to choose from and the coffee was very good. We did not take advantage of the pool.

Reviewed on Jan 14, 2026

Opens in a new windowPear Tree Inn Sikeston
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

2.5 out of 5
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Jan 29 to Jan 30
$114 total
Jan 29 - Jan 30
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate ...
Very clean, staff pleasant and helpful

Reviewed on Jan 6, 2026

Opens in a new windowFairfield Inn & Suites by Marriott Sikeston
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $115 total per night from Feb 1 to Feb 2
$115 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. ...
The room was very clean and nicely appointed. The continental breakfast was good with hot food items and hard boiled eggs, oatmeal, fruit, etc. Price was reasonable.

Reviewed on Jan 10, 2026

Opens in a new windowHampton Inn Sikeston
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr Sikeston MO
Fully refundable
$93 nightly
The price is $105 total per night from Feb 8 to Feb 9
$105 total
Feb 8 - Feb 9
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Stay was excellent

Reviewed on Dec 26, 2025

Opens in a new windowHoliday Inn Express & Suites Sikeston Southwest by IHG
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 out of 5
100 Matthews Lane Sikeston MO
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $67 total per night from Jan 20 to Jan 21
$67 total
Jan 20 - Jan 21
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
Saw a baby roach but other than that no complaints

Reviewed on Jan 3, 2026

Opens in a new windowTravel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $81 total per night from Jan 25 to Jan 26
$81 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...
Everything about our stay (just the one night) was great.

Reviewed on Jan 15, 2026

Opens in a new windowBest Western Plus Sikeston
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $72 total per night from Jan 25 to Jan 26
$72 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
It was nice a hotel have to come back sometime

Reviewed on Jan 9, 2026

Opens in a new windowDays Inn and Suites by Wyndham Sikeston
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2 out of 5
2609 E Malone Ave Sikeston MO
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $68 total per night from Jan 20 to Jan 21
$68 total
Jan 20 - Jan 21
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...
Stayed with my kids for visitation

Reviewed on Jan 5, 2026

Opens in a new windowSuper 8 by Wyndham Sikeston/Miner Area
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Anniston?
Take some of the hassles out of traveling with kids by staying in a family-friendly Anniston hotel. From useful amenities to extra-helpful services, these stays feature perks that'll make your trip run like a dream: The whole gang will enjoy their time at Quality Inn Charleston I-57. A swimming pool and complimentary breakfast are just a few of the things that help make this place a favorite. Alternatively, spend your nights enjoying the comforts of Super 8 by Wyndham Charleston MO. Make the most of complimentary breakfast, pet-friendly facilities and more here.
Where can I find cheap hotels in Anniston?
At Travelocity you'll find really nice hotels in Anniston at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Anniston rather than in Anniston. We may find you even better rates, too.
How do I find the best Anniston hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Anniston then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Anniston?
The cheapest hotel in Anniston is $67. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Anniston?
There are 19 hotels in Anniston on Travelocity.
What are the best hotels in Anniston?
Anniston has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Anniston for you!
When is the best time to visit Anniston?
If you want the joy of a fun-filled trip in peak season, visit Anniston during March, April and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, February and October.
When is the cheapest time to stay in Anniston?
Based on historic data is usually the cheapest month to visit Anniston. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Anniston?
There are multiple hotels in Anniston that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Anniston. We have plenty of kid-friendly hotels in Anniston to choose from on Travelocity!
Why book a hotel in Anniston through Travelocity?
Because we have the top hotels in Anniston! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Anniston on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Anniston hotel reviews by fellow wanderers

Best Western Plus Sikeston

Best Western Plus Sikeston

5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Everything about our stay (just the one night) was great."
A verified traveler stayed at Best Western Plus Sikeston
Best Western Plus Sikeston

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