Explore top 2026 5 Star Hotels in Ortygia

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Top Ortygia 5 Star hotels

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

5 out of 5
Viale Mazzini, 12 Syracuse SR
Fully refundableReserve now, pay when you stay
$262 nightly
The price is $300 total per night from Apr 7 to Apr 8
$300 total
Apr 7 - Apr 8
Total with taxes and fees
This hotel features a restaurant, a rooftop terrace, and a bar/lounge. Take the beach shuttle and relax with sun loungers and beach umbrellas. WiFi in public ...
9/10 Wonderful! (585 reviews)
Beautiful facility, classic. Wonderful restaurant for breakfast and dinner.

Reviewed on Apr 1, 2026

Opens in a new windowGrand Hotel Ortigia Siracusa
Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection

5 out of 5
Via Riva Nazario Sauro Syracuse SR
Fully refundableReserve now, pay when you stay
$384 nightly
The price is $434 total per night from Apr 5 to Apr 6
$434 total
Apr 5 - Apr 6
Total with taxes and fees
A full-service spa, 2 restaurants, and a 24-hour gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.4/10 Exceptional! (259 reviews)
The hotel itself is a beautiful building with an interesting heritage as the main post office. The location is excellent offering a great starting point for a walking tour of Ortigia. Great stay.

Reviewed on Feb 5, 2026

Opens in a new windowOrtea Palace Hotel, Sicily, Autograph Collection
Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World

5 out of 5
Passeggio Adorno 10/12 Syracuse SR
Fully refundableReserve now, pay when you stay
$561 nightly
The price is $629 total per night from May 4 to May 5
$629 total
May 4 - May 5
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public areas, ...
9.6/10 Exceptional! (73 reviews)
Great hotel and saff

Reviewed on Oct 20, 2025

Opens in a new windowGrand Hotel Des Ètrangers - The Leading Hotels of the World
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Ortygia Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Ortygia to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Ortygia 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Ortygia before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Ortygia hotel reviews by fellow wanderers

Maecò Ortigia B&B

Maecò Ortigia B&B

5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"The breakfast menu was very diverse. Things were fresh and tasty. All varieties of coffee served. The people serving were exceptionally welcoming in hospitable. It was a wonderful place to start the day having a delicious breakfast. The property was wonderful one of our favorite places to stay during our three weeks of travel around Italy in Sicily Martina, who first greeted this was so thoughtful caring suggested places to go for history also places to eat, even where to get our laundry done she has an excellent Host and made the day id. I would stay here again in a heartbeat."
A verified traveler stayed at Maecò Ortigia B&B
Maecò Ortigia B&B

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