Explore top 2026 5 Star Hotels in Mendoza Wine Region

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Top Mendoza Wine Region 5 Star hotels

Park Hyatt Mendoza

Park Hyatt Mendoza

5 out of 5
Chile 1124 Mendoza Mendoza
Fully refundableReserve now, pay when you stay
$211 nightly
The price is $211 total per night from Dec 8 to Dec 9
$211 total
Dec 8 - Dec 9
This luxury hotel features an attached winery, a casino, and a full-service spa. Families will appreciate the onsite laundry facilities and in-room childcare. ...
9.2/10 Wonderful! (1,006 reviews)
"As usual, in our experience, Hyatt has excellent service, good breakfasts, and the property is always kept looking clean."

Reviewed on Nov 5, 2026

Opens in a new windowPark Hyatt Mendoza
Awasi Mendoza

Awasi Mendoza

5 out of 5
Calle Costa Flores Luján de Cuyo Mendoza
$1,148 nightly
The price is $1,148 total per night from Dec 6 to Dec 7
$1,148 total
Dec 6 - Dec 7
An attached winery and an outdoor pool are featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public areas and free airport ...
Opens in a new windowAwasi Mendoza
Andeluna Winery Lodge

Andeluna Winery Lodge

5 out of 5
11 RP89 Tupungato Mendoza
$339 nightly
The price is $339 total per night from Dec 2 to Dec 3
$339 total
Dec 2 - Dec 3
An attached winery and a restaurant are featured at this luxury lodge. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and ...
10/10 Exceptional! (52 reviews)
"All perfect!"

Reviewed on Oct 9, 2026

Opens in a new windowAndeluna Winery Lodge
Gaia Lodge

Gaia Lodge

5 out of 5
7 RP89 Tupungato Mendoza
$117 nightly
The price is $117 total per night from Nov 11 to Nov 12
$117 total
Nov 11 - Nov 12
This lodge doesn't skimp on freebies - guests receive free breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 2 conference ...
9.8/10 Exceptional! (121 reviews)
"Excellent service, food and lodging❤️recommended!"

Reviewed on Nov 4, 2026

Opens in a new windowGaia Lodge
Susana Balbo Winemaker's House - Relais & Chateaux

Susana Balbo Winemaker's House - Relais & Chateaux

5 out of 5
Viamonte 5022 Chacras de Coria Mendoza
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, ...
9.8/10 Exceptional! (31 reviews)
"Attentive staff that planned a wonderful itinerary. Great food and wine. We couldn’t ask for anything more!"

Reviewed on Mar 29, 2026

Opens in a new windowSusana Balbo Winemaker's House - Relais & Chateaux
Agrelo Vines Lodge

Agrelo Vines Lodge

5 out of 5
7821 Cochabamba Luján de Cuyo Mendoza
$370 nightly
The price is $370 total per night from Nov 10 to Nov 11
$370 total
Nov 10 - Nov 11
A seasonal outdoor pool, free self parking, and concierge services are featured at this lodge. Guests will appreciate free perks like continental breakfast and ...
9.8/10 Exceptional! (27 reviews)
"Excellent stay, fabulous location, facilities exactly as described - v comfortable with excellent breakfast. Minor issue with door alarm but highly recommend this spot. Views are amazing."

Reviewed on Aug 7, 2026

Opens in a new windowAgrelo Vines Lodge
Bodega Iaccarini Wine Lodge by BT Homes

Bodega Iaccarini Wine Lodge by BT Homes

5 out of 5
Calle Iaccarini y Calle Don Nicasio San Rafael Mendoza
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $86 total per night from Nov 11 to Nov 12
$86 total
Nov 11 - Nov 12
An attached winery and a restaurant are featured at this luxury apartment. Relax with a drink at the bar/lounge and enjoy free perks like continental breakfast ...
10/10 Exceptional! (2 reviews)
"Es el mejor alojamiento de San Rafael sin dudas. Es un poco alejado de la ciudad pero no necesitas ir a la ciudad ya que tienes todas las comodidades incluyendo delivery de comida premium. Este alojamiento rivaliza con los alojamientos de Agrelo que valen 10 veces mas."

Reviewed on Aug 17, 2026

Opens in a new windowBodega Iaccarini Wine Lodge by BT Homes
Rancho Adobe

Rancho Adobe

5 out of 5
Estancia Atamisque Ruta 89 S/N Tupungato Mendoza
This guesthouse features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free local cuisine breakfast each morning. A garden, ...
Opens in a new windowRancho Adobe
El Torreón Lodge

El Torreón Lodge

5 out of 5
Calle 7 & Calle 8 Potrerillos Mendoza
A seasonal outdoor pool, free self parking, and barbecue grills are featured at this lodge. A garden and a picnic area are also provided.
Opens in a new windowEl Torreón Lodge
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Mendoza Wine Region Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Mendoza Wine Region to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Mendoza Wine Region 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Mendoza Wine Region before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Mendoza Wine Region hotel reviews by fellow wanderers