Explore top 2025 5 Star Hotels in Cyclades Islands

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Top Cyclades Islands 5 Star hotels

Myconian Ambassador Hotel Relais & Chateaux

Platis Gialos, Mykonos, Mykonos Island

Fully refundableReserve now, pay when you stay

$287 nightly

$344 total

Sep 20 - Sep 21

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public areas, ...

Myconian Korali

Main Street, Mykonos Town, Mykonos

Fully refundableReserve now, pay when you stay

$273 nightly

$329 total

Oct 2 - Oct 3

Total with taxes and fees

A full-service spa and a restaurant are featured at this luxury hotel. Families will appreciate the onsite laundry facilities and in-room childcare. Enjoy the ...

Santo Pure Oia Suites & Villas

Oia, Santorini

$400 nightly

$472 total

Oct 4 - Oct 5

Total with taxes and fees

A full-service spa, 6 outdoor pools, and a hot tub are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public areas, ...

Palladium Hotel

Plati Yialos, Mykonos, Mykonos Island

Fully refundableReserve now, pay when you stay

$230 nightly

$279 total

Oct 3 - Oct 4

Total with taxes and fees

A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities and babysitting. ...

CAVO TAGOO MYKONOS

TAGOO MYKONOS, Mykonos

$587 nightly

$686 total

Oct 2 - Oct 3

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the gym and free perks like buffet breakfast and valet parking. Enjoy the sauna and ...

Costa Grand Resort & Spa

Kamari Beach, Santorini, Santorini Island

Fully refundableReserve now, pay when you stay

$164 nightly

$204 total

Sep 29 - Sep 30

Total with taxes and fees

A private beach, a full-service spa, and 7 outdoor pools are all featured at this luxury hotel. Relax with free beach cabanas, sun loungers, and beach umbrellas. ...

Andronis Arcadia Hotel

Oia, Santorini, Santorini Island

$498 nightly

$583 total

Oct 3 - Oct 4

Total with taxes and fees

A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Relax with a drink at one of the 2 poolside bars and enjoy free perks like ...

NOŪS Santorini

Mesaria, Santorini, Santorini Island

$283 nightly

$339 total

Oct 3 - Oct 4

Total with taxes and fees

A full-service spa, 2 restaurants, and a gym are all featured at this luxury resort. Enjoy the steam room and free perks like full breakfast and free self parking. ...

Saint John Hotel Villas & Spa

Aghios Ioannis Beach, Aghios Ioannis, Mykonos, Mykonos Island

$178 nightly

$221 total

Oct 2 - Oct 3

Total with taxes and fees

This luxury hotel features a private beach, a full-service spa, and 3 restaurants. Enjoy the indoor pool and perks like free valet parking and free WiFi. Enjoy ...

Antoperla Luxury Hotel & Spa

Perissa, Santorini

A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Enjoy the outdoor pool and free perks like buffet breakfast and free self ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cyclades Islands Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Cyclades Islands to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Cyclades Islands 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Cyclades Islands before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.