Explore top 2026 4 Star Hotels in Mendoza Wine Region

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Top Mendoza Wine Region 4 Star hotels

Huentala Hotel

Huentala Hotel

4 out of 5
Primitivo De La Reta 1007 Mendoza Mendoza
$112 nightly
The price is $112 total per night from Nov 8 to Nov 9
$112 total
Nov 8 - Nov 9
This hotel features an attached winery, a casino, and a full-service spa. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.6/10 Excellent! (995 reviews)
"Beautiful room - clean, comfortable beds and spacious. Great breakfast and restaurants on site."

Reviewed on Nov 6, 2026

Opens in a new windowHuentala Hotel
Sheraton Mendoza Hotel

Sheraton Mendoza Hotel

4.5 out of 5
Primitivo De La Reta 989 Mendoza Mendoza
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $138 total per night from Dec 1 to Dec 2
$138 total
Dec 1 - Dec 2
This luxury hotel features a casino, a full-service spa, and 3 restaurants. Bring the family and enjoy the free kid's club, playground, and arcade/game room. ...
9.2/10 Wonderful! (1,001 reviews)
"Good hotel, but it's outdated and some rooms need work. Beds and pillows weren't really comfortable. You can't add the points to your Marriott account if you book through Expedia."

Reviewed on Nov 1, 2026

Opens in a new windowSheraton Mendoza Hotel
Diplomatic Hotel

Diplomatic Hotel

4.5 out of 5
Belgrano 1041 Mendoza Mendoza
Fully refundableReserve now, pay when you stay
$187 nightly
The price is $187 total per night from Dec 8 to Dec 9
$187 total
Dec 8 - Dec 9
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Families will appreciate the onsite laundry facilities, kid-friendly ...
9.4/10 Exceptional! (1,004 reviews)
"The staff were very nice and helpful."

Reviewed on Nov 6, 2026

Opens in a new windowDiplomatic Hotel
Hilton Mendoza

Hilton Mendoza

4.5 out of 5
Acceso Este Lateral Norte 3292 Guaymallen Mendoza
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $128 total per night from Dec 1 to Dec 2
$128 total
Dec 1 - Dec 2
This luxury hotel features a casino, a full-service spa, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
9.2/10 Wonderful! (188 reviews)
"Good location. Comfortable rooms"

Reviewed on Nov 4, 2026

Opens in a new windowHilton Mendoza
Villaggio Hotel Boutique

Villaggio Hotel Boutique

4 out of 5
25 De Mayo 1010 Mendoza Mendoza
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $87 total per night from Dec 7 to Dec 8
$87 total
Dec 7 - Dec 8
A full-service spa and an outdoor pool are featured at this traditional hotel. Traveling on business? Take advantage of the business center, free WiFi in public ...
8.8/10 Excellent! (946 reviews)
"El staff fue muy amable, nos indicaron lugares donde pasar el día y almorzar, y el breakfast fue muy rico y variado."

Reviewed on Nov 3, 2026

Opens in a new windowVillaggio Hotel Boutique
Hualta Hotel Mendoza, Curio Collection By Hilton

Hualta Hotel Mendoza, Curio Collection By Hilton

4 out of 5
Primitivo de la Reta 1015 Mendoza
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $128 total per night from Dec 1 to Dec 2
$128 total
Dec 1 - Dec 2
A full-service spa, a 24-hour gym, and a restaurant are all featured at this hotel. Enjoy the seasonal outdoor pool and perks like free WiFi. Self parking and ...
9.4/10 Exceptional! (345 reviews)
"Great hotel. Very well designed room. A little noisy (outdoor noise from window and corridor). Very comfortable bed. Great pool and gym. Central location but perhaps not the buzziest part of Mendoza."

Reviewed on Nov 5, 2026

Opens in a new windowHualta Hotel Mendoza, Curio Collection By Hilton
Amérian Mendoza

Amérian Mendoza

4 out of 5
San Lorenzo 660 Mendoza Mendoza
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $74 total per night from Dec 8 to Dec 9
$74 total
Dec 8 - Dec 9
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
8.6/10 Excellent! (825 reviews)
"The location was fantastic and close to everything. Very walkable to sites, parks and good restaurants. The staff were also most friendly and extremely helpful for directions, recommendations and booking a tour for us. The only thing we would change is to have the room and bathroom given a refresh ..."

Reviewed on Oct 31, 2026

Opens in a new windowAmérian Mendoza
Raices Aconcagua Mendoza

Raices Aconcagua Mendoza

4 out of 5
San Lorenzo 545 Mendoza Mendoza
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $120 total per night from Dec 1 to Dec 2
$120 total
Dec 1 - Dec 2
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. There's ...
7.8/10 Good! (675 reviews)
"Nice breakfast, great location. Close to Aristides and at a walk distance from the Parque San Martin, if you like to do sport that is the place to go, the gym at the hotel is very well equipped and modern"

Reviewed on Oct 29, 2026

Opens in a new windowRaices Aconcagua Mendoza
Rosell Boher Winery Lodge & Spa

Rosell Boher Winery Lodge & Spa

4 out of 5
Servidumbre De Paso S/N Ugarteche Mendoza
Fully refundableReserve now, pay when you stay
$473 nightly
The price is $473 total per night from Nov 9 to Nov 10
$473 total
Nov 9 - Nov 10
This smoke-free lodge features an attached winery, a full-service spa, and a restaurant. Families will appreciate the onsite laundry facilities and in-room childcare. ...
Opens in a new windowRosell Boher Winery Lodge & Spa
NH Mendoza Cordillera

NH Mendoza Cordillera

4 out of 5
Avda.España, 1324 Mendoza Mendoza
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $122 total per night from Nov 22 to Nov 23
$122 total
Nov 22 - Nov 23
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
Opens in a new windowNH Mendoza Cordillera
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4 Star Hotels Mendoza Wine Region

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Mendoza Wine Region 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Mendoza Wine Region will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Mendoza Wine Region, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Mendoza Wine Region hotel reviews by fellow wanderers