Explore top 2026 4 Star Hotels in Historic Route 66

Name: The Chicago Hotel Collection - Magnificent Mile
Price range: $183 total
Rating: 7.8

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Top Historic Route 66 4 Star hotels

Hyatt Regency O'Hare Chicago

9300 Bryn Mawr Ave Rosemont IL

Fully refundableReserve now, pay when you stay

$135 nightly

$154 total

Jun 28 - Jun 29

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...

8.8/10 Excellent! (2,629 reviews)

"Good hotel for family and business trips. Conveniently located near O’Hare. Courteous staff and people of Chi."

Reviewed on Jun 7, 2026

Fairmont Chicago at Millennium Park

200 North Columbus Drive Chicago IL

Fully refundableReserve now, pay when you stay

$332 nightly

$394 total

Jun 21 - Jun 22

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities and in-room ...

8.8/10 Excellent! (2,178 reviews)

"The only good thing this property has going for it is its location. Everything else was very subpar. The price seemed nice online and going into it you get charged an arm and a leg for every little thing on the “snack bar” in the room. $20+ for a little thing of chocolates as small as a small bag ..."

Reviewed on Jun 7, 2026

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO

Fully refundableReserve now, pay when you stay

$138 nightly

$162 total

Jun 12 - Jun 13

Total with taxes and fees

This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...

8.6/10 Excellent! (4,104 reviews)

"The stay was excellent but when you are ready to leave getting your car is stressful we had to wait half-hour in line to retrieve our vehicle other than the stay was excellent"

Reviewed on Jun 7, 2026

InterContinental Chicago Magnificent Mile by IHG

505 N Michigan Ave Chicago IL

Fully refundable

$217 nightly

$259 total

Jul 6 - Jul 7

Total with taxes and fees

This luxury hotel includes 2 restaurants, an indoor pool, and a gym. Enjoy the sauna and perks like free WiFi. A bar/lounge, a 24-hour front desk, and a coffee ...

9.2/10 Wonderful! (3,084 reviews)

"Overall it was a very pleasant stay. The front desk person upon arrival was very friendly and polite."

Reviewed on Jun 6, 2026

Embassy Suites by Hilton Chicago Downtown River North

600 N State St Chicago IL

Fully refundableReserve now, pay when you stay

$205 nightly

$244 total

Jun 14 - Jun 15

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the gym and free full breakfast each morning. Valet parking, a business center, and ...

8.6/10 Excellent! (5,965 reviews)

"Amazing location. Hotel clean. Breakfast was great! Two complimentary drinks and snacks everyday was nice too! Only complaint is Air conditioner would reset on its own back to 75, no matter how many times I would change the setting. Made it way too warm when it was already hot and humid!"

Reviewed on Jun 8, 2026

The Chicago Hotel Collection Ambassador Gold Coast

1301 N State Pkwy Chicago IL

Fully refundableReserve now, pay when you stay

$162 nightly

$192 total

Jun 29 - Jun 30

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, ...

8.2/10 Very Good! (1,564 reviews)

"No water sold in the hotel. Instead they tried to upsell me in a package that I didn’t need. Think you need to change that policy. Our entire group of 4 rooms were disappointed."

Reviewed on Jun 7, 2026

L7 Chicago by LOTTE

225 N Wabash Ave Chicago IL

Fully refundableReserve now, pay when you stay

$332 nightly

$395 total

Jul 1 - Jul 2

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. WiFi in public areas is free. Valet parking, a coffee shop, and a lobby fireplace are also ...

9.6/10 Exceptional! (4,150 reviews)

"Appeared to be some maintenance issues with the elevators. Only one was working and the other looked as though it was not yet fully installed. Room temp of 67 felt like 70 and a bit of a stuffy smell in the room. Great location, great, friendly staff, good bed and pillows; quiet, too!"

Reviewed on Jun 8, 2026

Hotel Riu Plaza Chicago

150 East Ontario Street Chicago IL

$203 nightly

$242 total

Jun 30 - Jul 1

Total with taxes and fees

This hotel features 2 bars/lounges and a 24-hour gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy a meal from the restaurant ...

9.4/10 Exceptional! (4,377 reviews)

"Very clean big rooms and bathrooms. The rooms were quiet and very comfortable. The breakfast was very big with a lot of variety. From a location standpoint, the property is close to everything you want to do in Chicago."

Reviewed on Jun 7, 2026

Hotel Felix River North/Magnificent Mile

111 W Huron St Chicago IL

Fully refundableReserve now, pay when you stay

$174 nightly

$207 total

Jun 30 - Jul 1

Total with taxes and fees

This hotel features a 24-hour gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet ...

8.2/10 Very Good! (2,770 reviews)

"Staff was friendly and hotel was very clean! It’s in a great location and we enjoyed our room a lot! I took off a point because when we asked for fresh towels, they never came to our room and we had to ask again. But overall very comfortable and pleasant stay!"

Reviewed on Jun 7, 2026

The Chicago Hotel Collection - Magnificent Mile

166 E Superior Street Chicago IL

Fully refundable

$154 nightly

$183 total

Jun 28 - Jun 29

Total with taxes and fees

This boutique hotel's 2 restaurants, 2 bars/lounges, and 24-hour gym are some of the featured amenities. Business travelers can take advantage of the free WiFi ...

7.8/10 Good! (1,535 reviews)

"Very nice staff hotel was very clean and well maintained"

Reviewed on Jun 7, 2026

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4 Star Hotels Historic Route 66

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Historic Route 66 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Historic Route 66 will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Historic Route 66, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.