Explore top 2026 4 Star Hotels in Historic Route 66

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Top Historic Route 66 4 Star hotels

Embassy Suites by Hilton Chicago Downtown River North

Embassy Suites by Hilton Chicago Downtown River North

4 out of 5
600 N State St Chicago IL
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from Apr 12 to Apr 13
$149 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the gym and free full breakfast each morning. Valet parking, a business center, and ...
8.6/10 Excellent! (5,815 reviews)
Great experience

Reviewed on Apr 4, 2026

Opens in a new windowEmbassy Suites by Hilton Chicago Downtown River North
Hilton Chicago O'Hare Airport

Hilton Chicago O'Hare Airport

4 out of 5
O'Hare International Airport Chicago IL
Fully refundableReserve now, pay when you stay
$221 nightly
The price is $259 total per night from Apr 26 to Apr 27
$259 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features 2 restaurants, a bar/lounge, and A 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.4/10 Very Good! (2,242 reviews)
Convenience

Reviewed on Apr 3, 2026

Opens in a new windowHilton Chicago O'Hare Airport
Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago

4 out of 5
150 East Ontario Street Chicago IL
Fully refundableReserve now, pay when you stay
$146 nightly
The price is $172 total per night from Apr 5 to Apr 6
$172 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features 2 bars/lounges and a 24-hour gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy a meal from the restaurant ...
9.4/10 Exceptional! (3,713 reviews)
Lovely

Reviewed on Apr 3, 2026

Opens in a new windowHotel Riu Plaza Chicago
The Wade

The Wade

4.5 out of 5
644 N Lake Shore Dr Chicago IL
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $169 total per night from Apr 27 to Apr 28
$169 total
Apr 27 - Apr 28
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.4/10 Very Good! (1,769 reviews)
Clean room, great view, close to lake! Loved!

Reviewed on Apr 3, 2026

Opens in a new windowThe Wade
Little America Flagstaff

Little America Flagstaff

4 out of 5
2515 E Butler Ave Flagstaff AZ
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $119 total per night from Apr 19 to Apr 20
$119 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features a hot tub, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
9.8/10 Exceptional! (3,657 reviews)
This was a really nice resort style hotel. Spacious and recently updated rooms with comfortable beds. Nice pool and hot tub area along scenic grounds. Well kept and maintained with a very friendly and helpful staff. Would highly recommend if exploring the area. Also I should mention extremely clean ...

Reviewed on Apr 3, 2026

Opens in a new windowLittle America Flagstaff
River Spirit Casino Resort

River Spirit Casino Resort

4 out of 5
8330 Riverside Parkway Tulsa OK
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $169 total per night from Apr 5 to Apr 6
$169 total
Apr 5 - Apr 6
Total with taxes and fees
This resort features a casino, a full-service spa, and a nightclub. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9.4/10 Exceptional! (2,758 reviews)
Love River Spirit, highly recommend this casino resort!

Reviewed on Apr 2, 2026

Opens in a new windowRiver Spirit Casino Resort
Fairmont Chicago at Millennium Park

Fairmont Chicago at Millennium Park

4.5 out of 5
200 North Columbus Drive Chicago IL
$199 nightly
The price is $234 total per night from Apr 5 to Apr 6
$234 total
Apr 5 - Apr 6
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities and in-room ...
8.8/10 Excellent! (2,098 reviews)
Incredible weekend with Leaf spa on the bottom level and the overall staff exceeded my expectations way beyond I could even comprehend, very friendly and willing to go that extra mile to make sure your stay is a memorable one

Reviewed on Apr 3, 2026

Opens in a new windowFairmont Chicago at Millennium Park
Swissotel - Chicago

Swissotel - Chicago

4.5 out of 5
323 E Wacker Dr Chicago IL
Fully refundableReserve now, pay when you stay
$195 nightly
The price is $229 total per night from Apr 5 to Apr 6
$229 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features 2 bars/lounges and a 24-hour gym. Traveling on business? Take advantage of the business center, express check-in, and valet parking. A restaurant, ...
9/10 Wonderful! (3,236 reviews)
Really nice hotel with great views and amazing staff

Reviewed on Apr 3, 2026

Opens in a new windowSwissotel - Chicago
Hyatt Regency O'Hare Chicago

Hyatt Regency O'Hare Chicago

4 out of 5
9300 Bryn Mawr Ave Rosemont IL
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $154 total per night from Apr 5 to Apr 6
$154 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
8.8/10 Excellent! (2,453 reviews)
Our room was clean and the bed was very comfortable. I will note that we were supposed to be in a 425 square foot room with a decent sized bathroom but the room we were given was no larger that 200 square feet.

Reviewed on Apr 3, 2026

Opens in a new windowHyatt Regency O'Hare Chicago
Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel

Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel

4 out of 5
500 South Dearborn Street Chicago IL
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from Apr 26 to Apr 27
$149 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9.6/10 Exceptional! (1,226 reviews)
I loved this hotel. Very classy, well decorated combining the historic aspects of the area with the buildings original high quality finishings and making it all look seamless. With that said, the view was only that of a nearby brick building but it did keep it much more quiet. They even had earplugs ...

Reviewed on Apr 2, 2026

Opens in a new windowBluegreen Vacations Hotel Blake, an Ascend Collection Hotel
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4 Star Hotels Historic Route 66

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Historic Route 66 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Historic Route 66 will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Historic Route 66, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Historic Route 66 hotel reviews by fellow wanderers

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