American Airlines Flight 6216 Deals & Information (2026/2027)

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American Airlines Flight 6216 Route Deals From $161

The cheapest prices found with in the last 7 days for return flights were $269 and $161 for one-way flights to O'Hare Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, May 22 - Mon, May 24
TYS
McGhee Tyson
ORD
O'Hare Intl.
$269 Roundtrip, found 1 hour ago
$269
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sat, May 22 from McGhee Tyson to O'Hare Intl., returning Mon, May 24, priced at $269 found 1 hour ago
Fri, Sep 4 - Mon, Sep 7
TYS
McGhee Tyson
ORD
O'Hare Intl.
$273 Roundtrip, found 5 hours ago
$273
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Fri, Sep 4 from McGhee Tyson to O'Hare Intl., returning Mon, Sep 7, priced at $273 found 5 hours ago
Sat, May 22 - Mon, May 24
TYS
McGhee Tyson
ORD
O'Hare Intl.
$274 Roundtrip, found 1 hour ago
$274
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sat, May 22 from McGhee Tyson to O'Hare Intl., returning Mon, May 24, priced at $274 found 1 hour ago
Fri, Sep 4 - Mon, Sep 7
TYS
McGhee Tyson
ORD
O'Hare Intl.
$283 Roundtrip, found 5 hours ago
$283
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Fri, Sep 4 from McGhee Tyson to O'Hare Intl., returning Mon, Sep 7, priced at $283 found 5 hours ago
Sat, May 22 - Mon, May 24
TYS
McGhee Tyson
ORD
O'Hare Intl.
$284 Roundtrip, found 1 hour ago
$284
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sat, May 22 from McGhee Tyson to O'Hare Intl., returning Mon, May 24, priced at $284 found 1 hour ago
Fri, Sep 4 - Mon, Sep 7
TYS
McGhee Tyson
ORD
O'Hare Intl.
$288 Roundtrip, found 5 hours ago
$288
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Fri, Sep 4 from McGhee Tyson to O'Hare Intl., returning Mon, Sep 7, priced at $288 found 5 hours ago
Fri, Oct 2 - Tue, Oct 6
TYS
McGhee Tyson
ORD
O'Hare Intl.
$289 Roundtrip, found 11 hours ago
$289
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Fri, Oct 2 from McGhee Tyson to O'Hare Intl., returning Tue, Oct 6, priced at $289 found 11 hours ago
Wed, Aug 12 - Sun, Aug 16
TYS
McGhee Tyson
ORD
O'Hare Intl.
$293 Roundtrip, found 13 hours ago
$293
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Aug 12 from McGhee Tyson to O'Hare Intl., returning Sun, Aug 16, priced at $293 found 13 hours ago
Sat, May 22 - Mon, May 24
TYS
McGhee Tyson
ORD
O'Hare Intl.
$294 Roundtrip, found 1 hour ago
$294
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sat, May 22 from McGhee Tyson to O'Hare Intl., returning Mon, May 24, priced at $294 found 1 hour ago
Fri, Sep 4 - Tue, Sep 8
TYS
McGhee Tyson
ORD
O'Hare Intl.
$298 Roundtrip, found 11 hours ago
$298
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Fri, Sep 4 from McGhee Tyson to O'Hare Intl., returning Tue, Sep 8, priced at $298 found 11 hours ago