American Airlines Flight 5388 Deals & Information (2025/2026)

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American Airlines Flight 5388 Route Deals From $118

The cheapest prices found with in the last 7 days for return flights were $216 and $118 for one-way flights to Northwest Florida Regional for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Sep 13 - Wed, Sep 17
DCA
Ronald Reagan Washington National
VPS
Northwest Florida Regional
$216 Roundtrip, found 2 days ago
$216
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Sep 13 from Ronald Reagan Washington National to Northwest Florida Regional, returning Wed, Sep 17, priced at $216 found 2 days ago
Fri, Aug 29 - Sat, Aug 30
DCA
Ronald Reagan Washington National
VPS
Northwest Florida Regional
$219 Roundtrip, found 5 days ago
$219
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Aug 29 from Ronald Reagan Washington National to Northwest Florida Regional, returning Sat, Aug 30, priced at $219 found 5 days ago
Tue, Sep 16 - Mon, Sep 22
DCA
Ronald Reagan Washington National
VPS
Northwest Florida Regional
$225 Roundtrip, found 4 days ago
$225
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Sep 16 from Ronald Reagan Washington National to Northwest Florida Regional, returning Mon, Sep 22, priced at $225 found 4 days ago
Tue, Sep 16 - Mon, Sep 22
DCA
Ronald Reagan Washington National
VPS
Northwest Florida Regional
$225 Roundtrip, found 4 days ago
$225
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Sep 16 from Ronald Reagan Washington National to Northwest Florida Regional, returning Mon, Sep 22, priced at $225 found 4 days ago
Sat, Sep 13 - Wed, Sep 17
DCA
Ronald Reagan Washington National
VPS
Northwest Florida Regional
$232 Roundtrip, found 2 days ago
$232
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Sep 13 from Ronald Reagan Washington National to Northwest Florida Regional, returning Wed, Sep 17, priced at $232 found 2 days ago
Tue, Oct 7 - Tue, Oct 14
DCA
Ronald Reagan Washington National
VPS
Northwest Florida Regional
$298 Roundtrip, found 10 hours ago
$298
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Tue, Oct 7 from Ronald Reagan Washington National to Northwest Florida Regional, returning Tue, Oct 14, priced at $298 found 10 hours ago
Wed, Oct 29 - Mon, Nov 3
DCA
Ronald Reagan Washington National
VPS
Northwest Florida Regional
$329 Roundtrip, found 21 hours ago
$329
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Wed, Oct 29 from Ronald Reagan Washington National to Northwest Florida Regional, returning Mon, Nov 3, priced at $329 found 21 hours ago
Tue, Oct 7 - Tue, Oct 14
DCA
Ronald Reagan Washington National
VPS
Northwest Florida Regional
$330 Roundtrip, found 10 hours ago
$330
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Tue, Oct 7 from Ronald Reagan Washington National to Northwest Florida Regional, returning Tue, Oct 14, priced at $330 found 10 hours ago

Frequently asked questions

What route does flight number AA5388 take?
AA5388 takes around 1 hour and 25 minutes to jet directly from Craven Regional Airport (EWN) to CLT. We all know there's magic in the destination, but getting there is half the fun!
What kind of plane is on flight number AA5388?
Chances are you'll find yourself cruising aboard a Bombardier CRJ700 if you're on flight number AA5388. This flight usually sets off from Coastal Carolina Regional Airport and comes in to land at Charlotte Airport.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA5388 flight with Travelocity, please visit our Customer Service Portal.