American Airlines Flight 5359 Deals & Information (2026/2027)

Wander Wisely with exceptional service, 24/7 supportOpens in a new window

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

American Airlines Flight 5359 Route Deals From $169

The cheapest prices found with in the last 7 days for return flights were $356 and $169 for one-way flights to Charlotte-Douglas Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jan 17 - Tue, Jan 20
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$356 Roundtrip, found 12 hours ago
$356
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Jan 20, priced at $356 found 12 hours ago
Sat, Jan 17 - Tue, Jan 20
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$361 Roundtrip, found 12 hours ago
$361
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Jan 20, priced at $361 found 12 hours ago
Sat, Jan 17 - Tue, Jan 20
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$365 Roundtrip, found 12 hours ago
$365
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Jan 20, priced at $365 found 12 hours ago
Sat, Jan 31 - Sat, Feb 7
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$371 Roundtrip, found 3 days ago
$371
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Jan 31 from Des Moines Intl. to Charlotte-Douglas Intl., returning Sat, Feb 7, priced at $371 found 3 days ago
Sat, Apr 11 - Tue, Apr 14
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$375 Roundtrip, found 2 days ago
$375
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Apr 11 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Apr 14, priced at $375 found 2 days ago
Sat, Apr 11 - Tue, Apr 14
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$385 Roundtrip, found 2 days ago
$385
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Apr 11 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Apr 14, priced at $385 found 2 days ago
Sat, Jan 17 - Tue, Jan 20
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$390 Roundtrip, found 12 hours ago
$390
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Jan 20, priced at $390 found 12 hours ago
Sat, Jan 31 - Sat, Feb 7
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$393 Roundtrip, found 3 days ago
$393
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Jan 31 from Des Moines Intl. to Charlotte-Douglas Intl., returning Sat, Feb 7, priced at $393 found 3 days ago
Sat, Jan 31 - Sat, Feb 7
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$397 Roundtrip, found 3 days ago
$397
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Jan 31 from Des Moines Intl. to Charlotte-Douglas Intl., returning Sat, Feb 7, priced at $397 found 3 days ago
Sat, Jan 31 - Sat, Feb 7
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$403 Roundtrip, found 3 days ago
$403
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Jan 31 from Des Moines Intl. to Charlotte-Douglas Intl., returning Sat, Feb 7, priced at $403 found 3 days ago

Frequently asked questions

What route does flight number AA5359 take?
AA5359 flies direct from Evers Intl. Airport (JAN) to Ronald Reagan Washington National Airport (DCA). During this trip, expect to be in the air for 2 hours and 24 minutes. Consider booking ahead to get your favorite seat.
What kind of plane is on flight number AA5359?
Get ready to hop on board a Bombardier CRJ700 if you've reserved a seat on flight AA5359. Nearly all flights from Jackson Municipal Airport to National Airport are operated using this model of aircraft.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA5359 flight with Travelocity, please visit our Customer Service Portal.