American Airlines Flight 5359 Deals & Information (2025/2026)

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American Airlines Flight 5359 Route Deals From $169

The cheapest prices found with in the last 7 days for return flights were $325 and $169 for one-way flights to Charlotte-Douglas Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jan 17 - Tue, Jan 20
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$325 Roundtrip, found 12 hours ago
$325
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Jan 20, priced at $325 found 12 hours ago
Sat, Jan 17 - Tue, Jan 20
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$353 Roundtrip, found 12 hours ago
$353
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Jan 20, priced at $353 found 12 hours ago
Tue, Mar 17 - Tue, Mar 24
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$373 Roundtrip, found 4 days ago
$373
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Mar 17 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Mar 24, priced at $373 found 4 days ago
Sat, Apr 11 - Tue, Apr 14
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$375 Roundtrip, found 1 day ago
$375
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Apr 11 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Apr 14, priced at $375 found 1 day ago
Tue, Mar 17 - Tue, Mar 24
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$383 Roundtrip, found 4 days ago
$383
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Mar 17 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Mar 24, priced at $383 found 4 days ago
Sat, Apr 11 - Tue, Apr 14
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$385 Roundtrip, found 1 day ago
$385
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Apr 11 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Apr 14, priced at $385 found 1 day ago
Sat, Jan 17 - Tue, Jan 20
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$404 Roundtrip, found 12 hours ago
$404
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Jan 20, priced at $404 found 12 hours ago
Thu, Jun 25 - Sat, Jun 27
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$409 Roundtrip, found 1 day ago
$409
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Jun 25 from Des Moines Intl. to Charlotte-Douglas Intl., returning Sat, Jun 27, priced at $409 found 1 day ago
Thu, Jun 25 - Sat, Jun 27
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$419 Roundtrip, found 1 day ago
$419
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Jun 25 from Des Moines Intl. to Charlotte-Douglas Intl., returning Sat, Jun 27, priced at $419 found 1 day ago
Sat, Jan 17 - Tue, Jan 20
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$420 Roundtrip, found 12 hours ago
$420
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Jan 20, priced at $420 found 12 hours ago
Thu, Jan 1 - Tue, Jan 6
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$426 Roundtrip, found 2 days ago
$426
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Jan 1 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Jan 6, priced at $426 found 2 days ago
Tue, Mar 17 - Tue, Mar 24
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$428 Roundtrip, found 4 days ago
$428
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Mar 17 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Mar 24, priced at $428 found 4 days ago
Sat, Apr 11 - Tue, Apr 14
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$430 Roundtrip, found 1 day ago
$430
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Apr 11 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Apr 14, priced at $430 found 1 day ago
Tue, Mar 17 - Tue, Mar 24
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$431 Roundtrip, found 4 days ago
$431
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Mar 17 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Mar 24, priced at $431 found 4 days ago
Sat, Apr 11 - Tue, Apr 14
DSM
Des Moines Intl.
CLT
Charlotte-Douglas Intl.
$433 Roundtrip, found 1 day ago
$433
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Apr 11 from Des Moines Intl. to Charlotte-Douglas Intl., returning Tue, Apr 14, priced at $433 found 1 day ago

Frequently asked questions

What route does flight number AA5359 take?
AA5359 flies direct from Evers Intl. Airport (JAN) to Ronald Reagan Washington National Airport (DCA). During this trip, expect to be in the air for 2 hours and 24 minutes. Consider booking ahead to get your favorite seat.
What kind of plane is on flight number AA5359?
Get ready to hop on board a Bombardier CRJ700 if you've reserved a seat on flight AA5359. Nearly all flights from Jackson Municipal Airport to National Airport are operated using this model of aircraft.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA5359 flight with Travelocity, please visit our Customer Service Portal.