American Airlines Flight 4506 Deals & Information (2025/2026)

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American Airlines Flight 4506 Route Deals From $191

The cheapest prices found with in the last 7 days for return flights were $161 and $191 for one-way flights to Columbia Metropolitan for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Nov 12 - Tue, Nov 18
LGA
LaGuardia
CAE
Columbia Metropolitan
$161 Roundtrip, found 10 hours ago
$161
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Nov 12 from LaGuardia to Columbia Metropolitan, returning Tue, Nov 18, priced at $161 found 10 hours ago
Tue, Nov 11 - Sat, Nov 15
LGA
LaGuardia
CAE
Columbia Metropolitan
$206 Roundtrip, found 10 hours ago
$206
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Tue, Nov 11 from LaGuardia to Columbia Metropolitan, returning Sat, Nov 15, priced at $206 found 10 hours ago
Wed, Nov 5 - Tue, Nov 11
LGA
LaGuardia
CAE
Columbia Metropolitan
$210 Roundtrip, found 1 day ago
$210
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Nov 5 from LaGuardia to Columbia Metropolitan, returning Tue, Nov 11, priced at $210 found 1 day ago
Wed, Nov 12 - Mon, Nov 17
LGA
LaGuardia
CAE
Columbia Metropolitan
$211 Roundtrip, found 10 hours ago
$211
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Nov 12 from LaGuardia to Columbia Metropolitan, returning Mon, Nov 17, priced at $211 found 10 hours ago

Frequently asked questions

What route does flight number AA4506 take?
AA4506 serves multiple routes, but the most common is between Nashville International Airport and Raleigh, NC Airport (RDU-Raleigh - Durham Intl.). If on a non-stop flight, you'll disembark the plane in roughly 1 hour and 34 minutes. Multi-stop flights can also operate under the same number, as can services on other routes.
What kind of plane is on flight number AA4506?
AA4506 is a flight number that's used on many different routes. If you're booked on its most popular route, Nashville International Airport to Raleigh–Durham Airport, chances are you'll be boarding the Embraer 175.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4506 flight with Travelocity, please visit our Customer Service Portal.