American Airlines Flight 4423 Deals & Information (2026/2027)

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American Airlines Flight 4423 Route Deals From $169

The cheapest prices found with in the last 7 days for return flights were $325 and $169 for one-way flights to Greenville-Spartanburg Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Aug 11 - Sat, Aug 15
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$325 Roundtrip, found 3 days ago
$325
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Aug 11 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Aug 15, priced at $325 found 3 days ago
Tue, Aug 11 - Sat, Aug 15
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$331 Roundtrip, found 3 days ago
$331
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Aug 11 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Aug 15, priced at $331 found 3 days ago
Tue, Aug 11 - Sat, Aug 15
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$341 Roundtrip, found 3 days ago
$341
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Aug 11 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Aug 15, priced at $341 found 3 days ago
Tue, Jun 30 - Sat, Jul 11
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$359 Roundtrip, found 1 day ago
$359
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jun 30 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Jul 11, priced at $359 found 1 day ago
Sat, Aug 1 - Sat, Aug 8
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$370 Roundtrip, found 2 days ago
$370
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Aug 1 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Aug 8, priced at $370 found 2 days ago
Tue, Jun 30 - Sat, Jul 11
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$373 Roundtrip, found 1 day ago
$373
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jun 30 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Jul 11, priced at $373 found 1 day ago
Sat, Jun 20 - Wed, Jul 22
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$374 Roundtrip, found 4 hours ago
$374
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Sat, Jun 20 from LaGuardia to Greenville-Spartanburg Intl., returning Wed, Jul 22, priced at $374 found 4 hours ago
Tue, Aug 11 - Sat, Aug 15
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$375 Roundtrip, found 3 days ago
$375
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Aug 11 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Aug 15, priced at $375 found 3 days ago
Tue, Jun 30 - Sat, Jul 11
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$384 Roundtrip, found 1 day ago
$384
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jun 30 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Jul 11, priced at $384 found 1 day ago
Sat, Jun 20 - Wed, Jul 22
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$394 Roundtrip, found 4 hours ago
$394
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Sat, Jun 20 from LaGuardia to Greenville-Spartanburg Intl., returning Wed, Jul 22, priced at $394 found 4 hours ago
Sat, Jun 20 - Wed, Jul 22
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$395 Roundtrip, found 4 hours ago
$395
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Sat, Jun 20 from LaGuardia to Greenville-Spartanburg Intl., returning Wed, Jul 22, priced at $395 found 4 hours ago
Sat, Jun 20 - Wed, Jul 22
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$405 Roundtrip, found 4 hours ago
$405
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Sat, Jun 20 from LaGuardia to Greenville-Spartanburg Intl., returning Wed, Jul 22, priced at $405 found 4 hours ago
Fri, Jul 3 - Tue, Jul 7
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$408 Roundtrip, found 10 hours ago
$408
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Fri, Jul 3 from LaGuardia to Greenville-Spartanburg Intl., returning Tue, Jul 7, priced at $408 found 10 hours ago
Fri, Jul 3 - Tue, Jul 7
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$418 Roundtrip, found 10 hours ago
$418
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Fri, Jul 3 from LaGuardia to Greenville-Spartanburg Intl., returning Tue, Jul 7, priced at $418 found 10 hours ago

Frequently asked questions

What route does flight number AA4423 take?
AA4423 is used on multiple routes. Most commonly, AA4423 flies direct from Hopkins Intl. Airport (CLE) to O'Hare Airport. If you have a ticket on this route, you'll be in the air for 1 hour and 40 minutes.
What kind of plane is on flight number AA4423?
There's a good chance you'll be on an Embraer RJ145 if you're flying from Cleveland Hopkins Intl. Airport to O'Hare Intl. Airport (ORD), a popular route for flight number AA4423.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4423 flight with Travelocity, please visit our Customer Service Portal.