American Airlines Flight 4423 Deals & Information (2026/2027)

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American Airlines Flight 4423 Route Deals From $171

The cheapest prices found with in the last 7 days for return flights were $289 and $171 for one-way flights to Greenville-Spartanburg Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Sep 23 - Mon, Sep 28
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$289 Roundtrip, found 1 day ago
$289
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 23 from LaGuardia to Greenville-Spartanburg Intl., returning Mon, Sep 28, priced at $289 found 1 day ago
Fri, Jul 3 - Tue, Jul 7
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$296 Roundtrip, found 14 hours ago
$296
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Fri, Jul 3 from LaGuardia to Greenville-Spartanburg Intl., returning Tue, Jul 7, priced at $296 found 14 hours ago
Wed, Sep 16 - Mon, Sep 21
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$299 Roundtrip, found 1 day ago
$299
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 16 from LaGuardia to Greenville-Spartanburg Intl., returning Mon, Sep 21, priced at $299 found 1 day ago
Fri, Jul 3 - Tue, Jul 7
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$306 Roundtrip, found 14 hours ago
$306
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Fri, Jul 3 from LaGuardia to Greenville-Spartanburg Intl., returning Tue, Jul 7, priced at $306 found 14 hours ago
Wed, Sep 23 - Mon, Sep 28
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$320 Roundtrip, found 1 day ago
$320
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 23 from LaGuardia to Greenville-Spartanburg Intl., returning Mon, Sep 28, priced at $320 found 1 day ago
Tue, Jun 16 - Sat, Jun 20
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$321 Roundtrip, found 2 days ago
$321
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jun 16 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Jun 20, priced at $321 found 2 days ago
Fri, Jul 3 - Tue, Jul 7
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$327 Roundtrip, found 14 hours ago
$327
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Fri, Jul 3 from LaGuardia to Greenville-Spartanburg Intl., returning Tue, Jul 7, priced at $327 found 14 hours ago
Mon, Jun 22 - Sat, Jun 27
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$329 Roundtrip, found 5 days ago
$329
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Jun 22 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Jun 27, priced at $329 found 5 days ago
Sat, Aug 1 - Sun, Aug 9
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$330 Roundtrip, found 16 hours ago
$330
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Sat, Aug 1 from LaGuardia to Greenville-Spartanburg Intl., returning Sun, Aug 9, priced at $330 found 16 hours ago
Fri, Jul 31 - Sat, Aug 1
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$342 Roundtrip, found 3 days ago
$342
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Jul 31 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Aug 1, priced at $342 found 3 days ago
Thu, Dec 31 - Fri, Jan 1
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$344 Roundtrip, found 5 days ago
$344
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Dec 31 from LaGuardia to Greenville-Spartanburg Intl., returning Fri, Jan 1, priced at $344 found 5 days ago
Tue, Jun 16 - Sat, Jun 20
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$347 Roundtrip, found 2 days ago
$347
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jun 16 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Jun 20, priced at $347 found 2 days ago
Thu, Jun 11 - Mon, Aug 31
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$347 Roundtrip, found 3 days ago
$347
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Jun 11 from LaGuardia to Greenville-Spartanburg Intl., returning Mon, Aug 31, priced at $347 found 3 days ago

Frequently asked questions

What route does flight number AA4423 take?
AA4423 is used on multiple routes. Most commonly, AA4423 flies direct from Hopkins Intl. Airport (CLE) to O'Hare Airport. If you have a ticket on this route, you'll be in the air for 1 hour and 40 minutes.
What kind of plane is on flight number AA4423?
There's a good chance you'll be on an Embraer RJ145 if you're flying from Cleveland Hopkins Intl. Airport to O'Hare Intl. Airport (ORD), a popular route for flight number AA4423.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4423 flight with Travelocity, please visit our Customer Service Portal.