American Airlines Flight 4423 Deals & Information (2026/2027)

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American Airlines Flight 4423 Route Deals From $149

The cheapest prices found with in the last 7 days for return flights were $288 and $149 for one-way flights to Greenville-Spartanburg Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Jul 13 - Tue, Jul 21
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$288 Roundtrip, found 6 days ago
$288
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Jul 13 from LaGuardia to Greenville-Spartanburg Intl., returning Tue, Jul 21, priced at $288 found 6 days ago
Sat, Jul 18 - Mon, Jul 20
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$310 Roundtrip, found 6 days ago
$310
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Jul 18 from LaGuardia to Greenville-Spartanburg Intl., returning Mon, Jul 20, priced at $310 found 6 days ago
Sat, Jul 18 - Mon, Jul 20
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$320 Roundtrip, found 6 days ago
$320
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Jul 18 from LaGuardia to Greenville-Spartanburg Intl., returning Mon, Jul 20, priced at $320 found 6 days ago
Tue, Aug 11 - Sat, Aug 15
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$325 Roundtrip, found 3 days ago
$325
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Aug 11 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Aug 15, priced at $325 found 3 days ago
Tue, Aug 11 - Sat, Aug 15
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$331 Roundtrip, found 3 days ago
$331
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Aug 11 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Aug 15, priced at $331 found 3 days ago
Mon, Jul 13 - Tue, Jul 21
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$333 Roundtrip, found 6 days ago
$333
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Jul 13 from LaGuardia to Greenville-Spartanburg Intl., returning Tue, Jul 21, priced at $333 found 6 days ago
Tue, Aug 11 - Sat, Aug 15
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$341 Roundtrip, found 3 days ago
$341
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Aug 11 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Aug 15, priced at $341 found 3 days ago
Sat, Jul 18 - Mon, Jul 20
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$343 Roundtrip, found 6 days ago
$343
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Jul 18 from LaGuardia to Greenville-Spartanburg Intl., returning Mon, Jul 20, priced at $343 found 6 days ago
Tue, Jun 30 - Sat, Jul 11
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$359 Roundtrip, found 20 hours ago
$359
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Tue, Jun 30 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Jul 11, priced at $359 found 20 hours ago
Sat, Aug 1 - Sat, Aug 8
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$370 Roundtrip, found 2 days ago
$370
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Aug 1 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Aug 8, priced at $370 found 2 days ago
Tue, Jun 30 - Sat, Jul 11
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$373 Roundtrip, found 20 hours ago
$373
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Tue, Jun 30 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Jul 11, priced at $373 found 20 hours ago
Tue, Aug 11 - Sat, Aug 15
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$375 Roundtrip, found 3 days ago
$375
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Aug 11 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Aug 15, priced at $375 found 3 days ago
Tue, Jun 30 - Sat, Jul 11
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$384 Roundtrip, found 20 hours ago
$384
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Tue, Jun 30 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Jul 11, priced at $384 found 20 hours ago
Tue, Jun 30 - Sat, Jul 11
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$392 Roundtrip, found 20 hours ago
$392
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Tue, Jun 30 from LaGuardia to Greenville-Spartanburg Intl., returning Sat, Jul 11, priced at $392 found 20 hours ago
Fri, Jul 3 - Tue, Jul 7
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$395 Roundtrip, found 3 hours ago
$395
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Fri, Jul 3 from LaGuardia to Greenville-Spartanburg Intl., returning Tue, Jul 7, priced at $395 found 3 hours ago
Fri, Jul 3 - Tue, Jul 7
LGA
LaGuardia
GSP
Greenville-Spartanburg Intl.
$408 Roundtrip, found 3 hours ago
$408
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Fri, Jul 3 from LaGuardia to Greenville-Spartanburg Intl., returning Tue, Jul 7, priced at $408 found 3 hours ago

Frequently asked questions

What route does flight number AA4423 take?
AA4423 is used on multiple routes. Most commonly, AA4423 flies direct from Hopkins Intl. Airport (CLE) to O'Hare Airport. If you have a ticket on this route, you'll be in the air for 1 hour and 40 minutes.
What kind of plane is on flight number AA4423?
There's a good chance you'll be on an Embraer RJ145 if you're flying from Cleveland Hopkins Intl. Airport to O'Hare Intl. Airport (ORD), a popular route for flight number AA4423.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4423 flight with Travelocity, please visit our Customer Service Portal.