American Airlines Flight 4423 Deals & Information (2026/2027)

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American Airlines Flight 4423 Route Deals From $131

The cheapest prices found with in the last 7 days for return flights were $239 and $131 for one-way flights to Buffalo Niagara Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Jun 2 - Tue, Jun 9
ORD
O'Hare Intl.
BUF
Buffalo Niagara Intl.
$239 Roundtrip, found 4 days ago
$239
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Jun 2 from O'Hare Intl. to Buffalo Niagara Intl., returning Tue, Jun 9, priced at $239 found 4 days ago
Wed, Jul 29 - Sun, Aug 2
ORD
O'Hare Intl.
BUF
Buffalo Niagara Intl.
$249 Roundtrip, found 15 hours ago
$249
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Wed, Jul 29 from O'Hare Intl. to Buffalo Niagara Intl., returning Sun, Aug 2, priced at $249 found 15 hours ago
Tue, Sep 29 - Tue, Oct 6
ORD
O'Hare Intl.
BUF
Buffalo Niagara Intl.
$258 Roundtrip, found 2 days ago
$258
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Sep 29 from O'Hare Intl. to Buffalo Niagara Intl., returning Tue, Oct 6, priced at $258 found 2 days ago
Tue, Sep 29 - Tue, Oct 6
ORD
O'Hare Intl.
BUF
Buffalo Niagara Intl.
$265 Roundtrip, found 2 days ago
$265
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Sep 29 from O'Hare Intl. to Buffalo Niagara Intl., returning Tue, Oct 6, priced at $265 found 2 days ago
Tue, Sep 29 - Tue, Oct 6
ORD
O'Hare Intl.
BUF
Buffalo Niagara Intl.
$268 Roundtrip, found 2 days ago
$268
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Sep 29 from O'Hare Intl. to Buffalo Niagara Intl., returning Tue, Oct 6, priced at $268 found 2 days ago
Mon, Jun 8 - Wed, Jun 10
ORD
O'Hare Intl.
BUF
Buffalo Niagara Intl.
$282 Roundtrip, found 1 hour ago
$282
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Mon, Jun 8 from O'Hare Intl. to Buffalo Niagara Intl., returning Wed, Jun 10, priced at $282 found 1 hour ago

Frequently asked questions

What route does flight number AA4423 take?
AA4423 is used on multiple routes. Most commonly, AA4423 flies direct from Hopkins Intl. Airport (CLE) to O'Hare Airport. If you have a ticket on this route, you'll be in the air for 1 hour and 40 minutes.
What kind of plane is on flight number AA4423?
There's a good chance you'll be on an Embraer RJ145 if you're flying from Cleveland Hopkins Intl. Airport to O'Hare Intl. Airport (ORD), a popular route for flight number AA4423.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4423 flight with Travelocity, please visit our Customer Service Portal.