American Airlines Flight 388 Deals & Information (2026/2027)

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American Airlines Flight 388 Route Deals From $49

The cheapest prices found with in the last 7 days for return flights were $97 and $49 for one-way flights to O'Hare Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Mar 27 - Sat, Mar 28
PIT
Pittsburgh Intl.
ORD
O'Hare Intl.
$97 Roundtrip, found 3 hours ago
$97
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Fri, Mar 27 from Pittsburgh Intl. to O'Hare Intl., returning Sat, Mar 28, priced at $97 found 3 hours ago
Fri, Mar 27 - Sat, Mar 28
PIT
Pittsburgh Intl.
ORD
O'Hare Intl.
$127 Roundtrip, found 3 hours ago
$127
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Fri, Mar 27 from Pittsburgh Intl. to O'Hare Intl., returning Sat, Mar 28, priced at $127 found 3 hours ago
Mon, Mar 23 - Tue, Mar 24
PIT
Pittsburgh Intl.
ORD
O'Hare Intl.
$139 Roundtrip, found 4 hours ago
$139
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Mon, Mar 23 from Pittsburgh Intl. to O'Hare Intl., returning Tue, Mar 24, priced at $139 found 4 hours ago
Mon, Mar 23 - Tue, Mar 24
PIT
Pittsburgh Intl.
ORD
O'Hare Intl.
$147 Roundtrip, found 4 hours ago
$147
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Mon, Mar 23 from Pittsburgh Intl. to O'Hare Intl., returning Tue, Mar 24, priced at $147 found 4 hours ago
Mon, May 11 - Tue, May 12
PIT
Pittsburgh Intl.
ORD
O'Hare Intl.
$157 Roundtrip, found 2 days ago
$157
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, May 11 from Pittsburgh Intl. to O'Hare Intl., returning Tue, May 12, priced at $157 found 2 days ago
Mon, May 11 - Tue, May 12
PIT
Pittsburgh Intl.
ORD
O'Hare Intl.
$169 Roundtrip, found 2 days ago
$169
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, May 11 from Pittsburgh Intl. to O'Hare Intl., returning Tue, May 12, priced at $169 found 2 days ago
Thu, Jul 30 - Tue, Aug 4
PIT
Pittsburgh Intl.
ORD
O'Hare Intl.
$179 Roundtrip, found 14 hours ago
$179
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Thu, Jul 30 from Pittsburgh Intl. to O'Hare Intl., returning Tue, Aug 4, priced at $179 found 14 hours ago
Thu, Jul 30 - Tue, Aug 4
PIT
Pittsburgh Intl.
ORD
O'Hare Intl.
$181 Roundtrip, found 14 hours ago
$181
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Thu, Jul 30 from Pittsburgh Intl. to O'Hare Intl., returning Tue, Aug 4, priced at $181 found 14 hours ago
Fri, Mar 27 - Sat, Mar 28
PIT
Pittsburgh Intl.
ORD
O'Hare Intl.
$183 Roundtrip, found 3 hours ago
$183
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Fri, Mar 27 from Pittsburgh Intl. to O'Hare Intl., returning Sat, Mar 28, priced at $183 found 3 hours ago
Wed, Apr 22 - Sun, Apr 26
PIT
Pittsburgh Intl.
ORD
O'Hare Intl.
$188 Roundtrip, found 5 days ago
$188
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Apr 22 from Pittsburgh Intl. to O'Hare Intl., returning Sun, Apr 26, priced at $188 found 5 days ago
Thu, Mar 19 - Sat, Mar 21
PIT
Pittsburgh Intl.
ORD
O'Hare Intl.
$189 Roundtrip, found 3 hours ago
$189
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Thu, Mar 19 from Pittsburgh Intl. to O'Hare Intl., returning Sat, Mar 21, priced at $189 found 3 hours ago

Frequently asked questions

What route does flight number AA388 take?
AA388 takes several routes. The most frequently flown is Dallas-Fort Worth Intl. Airport (DFW) to Fort Walton Beach, FL Airport (VPS-Northwest Florida Regional), which flies direct. This service generally takes 2 hours and 4 minutes. That said, there may be other flights with this number that have one or more stops.
What kind of plane is on flight number AA388?
It's more than likely you'll be hopping on board the Airbus A320 if you're on flight number AA388 from DFW to Northwest Florida Regional Airport (VPS). It's the most commonly used aircraft on this route.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA388 flight with Travelocity, please visit our Customer Service Portal.