American Airlines Flight 380 Deals & Information (2025/2026)

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Frequently asked questions

What route does flight number AA380 take?
AA380 takes a number of routes. The most popular is between Charlotte Airport and STL, which flies direct. This flight takes roughly 1 hour and 57 minutes. That said, you might find other flights with the same number that have one or more stops.
What kind of plane is on flight number AA380?
AA380 is a flight number that is used on many routes. If you're booked on its most popular one, Charlotte-Douglas Intl. Airport (CLT) to St. Louis, MO Airport (STL-Lambert-St. Louis Intl.), chances are you'll be hopping on board the Boeing 737-800.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA380 flight with Travelocity, please visit our Customer Service Portal.