American Airlines Flight AA5621 Deals & Information (2025/2026)

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American Airlines Flight 5621 Route Deals From $171

The cheapest prices found with in the last 7 days for return flights were $352 and $171 for one-way flights to Philadelphia Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Nov 8 - Wed, Nov 12
GSP
Greenville-Spartanburg Intl.
PHL
Philadelphia Intl.
$352 Roundtrip, found 2 days ago
$352
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Nov 8 from Greenville-Spartanburg Intl. to Philadelphia Intl., returning Wed, Nov 12, priced at $352 found 2 days ago
Sat, Dec 13 - Mon, Dec 15
GSP
Greenville-Spartanburg Intl.
PHL
Philadelphia Intl.
$360 Roundtrip, found 1 day ago
$360
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Dec 13 from Greenville-Spartanburg Intl. to Philadelphia Intl., returning Mon, Dec 15, priced at $360 found 1 day ago
Sat, Nov 8 - Wed, Nov 12
GSP
Greenville-Spartanburg Intl.
PHL
Philadelphia Intl.
$366 Roundtrip, found 2 days ago
$366
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Nov 8 from Greenville-Spartanburg Intl. to Philadelphia Intl., returning Wed, Nov 12, priced at $366 found 2 days ago
Sat, Nov 8 - Wed, Nov 12
GSP
Greenville-Spartanburg Intl.
PHL
Philadelphia Intl.
$371 Roundtrip, found 2 days ago
$371
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Nov 8 from Greenville-Spartanburg Intl. to Philadelphia Intl., returning Wed, Nov 12, priced at $371 found 2 days ago
Wed, Oct 29 - Sat, Nov 1
GSP
Greenville-Spartanburg Intl.
PHL
Philadelphia Intl.
$373 Roundtrip, found 2 days ago
$373
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Oct 29 from Greenville-Spartanburg Intl. to Philadelphia Intl., returning Sat, Nov 1, priced at $373 found 2 days ago
Sat, Sep 20 - Sun, Sep 28
GSP
Greenville-Spartanburg Intl.
PHL
Philadelphia Intl.
$375 Roundtrip, found 17 hours ago
$375
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Sat, Sep 20 from Greenville-Spartanburg Intl. to Philadelphia Intl., returning Sun, Sep 28, priced at $375 found 17 hours ago
Wed, Oct 29 - Sat, Nov 1
GSP
Greenville-Spartanburg Intl.
PHL
Philadelphia Intl.
$378 Roundtrip, found 2 days ago
$378
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Oct 29 from Greenville-Spartanburg Intl. to Philadelphia Intl., returning Sat, Nov 1, priced at $378 found 2 days ago
Sat, Oct 11 - Tue, Oct 14
GSP
Greenville-Spartanburg Intl.
PHL
Philadelphia Intl.
$379 Roundtrip, found 4 days ago
$379
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Oct 11 from Greenville-Spartanburg Intl. to Philadelphia Intl., returning Tue, Oct 14, priced at $379 found 4 days ago
Sat, Nov 8 - Wed, Nov 12
GSP
Greenville-Spartanburg Intl.
PHL
Philadelphia Intl.
$381 Roundtrip, found 2 days ago
$381
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Nov 8 from Greenville-Spartanburg Intl. to Philadelphia Intl., returning Wed, Nov 12, priced at $381 found 2 days ago
Wed, Oct 29 - Sat, Nov 1
GSP
Greenville-Spartanburg Intl.
PHL
Philadelphia Intl.
$388 Roundtrip, found 2 days ago
$388
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Oct 29 from Greenville-Spartanburg Intl. to Philadelphia Intl., returning Sat, Nov 1, priced at $388 found 2 days ago
Fri, Nov 7 - Tue, Nov 11
GSP
Greenville-Spartanburg Intl.
PHL
Philadelphia Intl.
$394 Roundtrip, found 2 days ago
$394
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Nov 7 from Greenville-Spartanburg Intl. to Philadelphia Intl., returning Tue, Nov 11, priced at $394 found 2 days ago
Sat, Dec 20 - Wed, Dec 31
GSP
Greenville-Spartanburg Intl.
PHL
Philadelphia Intl.
$403 Roundtrip, found 2 hours ago
$403
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Dec 20 from Greenville-Spartanburg Intl. to Philadelphia Intl., returning Wed, Dec 31, priced at $403 found 2 hours ago
Sat, Dec 20 - Wed, Dec 31
GSP
Greenville-Spartanburg Intl.
PHL
Philadelphia Intl.
$411 Roundtrip, found 2 hours ago
$411
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Dec 20 from Greenville-Spartanburg Intl. to Philadelphia Intl., returning Wed, Dec 31, priced at $411 found 2 hours ago