American Airlines Flight AA5341 Deals & Information (2025/2026)

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American Airlines Flight 5341 Route Deals From $170

The cheapest prices found with in the last 7 days for return flights were $189 and $170 for one-way flights to McGhee Tyson for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Oct 21 - Tue, Oct 28
ORD
O'Hare Intl.
TYS
McGhee Tyson
$189 Roundtrip, found 9 hours ago
$189
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Tue, Oct 21 from O'Hare Intl. to McGhee Tyson, returning Tue, Oct 28, priced at $189 found 9 hours ago
Sat, Aug 9 - Sat, Aug 16
ORD
O'Hare Intl.
TYS
McGhee Tyson
$193 Roundtrip, found 22 hours ago
$193
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Sat, Aug 9 from O'Hare Intl. to McGhee Tyson, returning Sat, Aug 16, priced at $193 found 22 hours ago
Sat, Sep 6 - Sat, Sep 13
ORD
O'Hare Intl.
TYS
McGhee Tyson
$214 Roundtrip, found 2 days ago
$214
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Sep 6 from O'Hare Intl. to McGhee Tyson, returning Sat, Sep 13, priced at $214 found 2 days ago
Tue, Oct 21 - Tue, Oct 28
ORD
O'Hare Intl.
TYS
McGhee Tyson
$224 Roundtrip, found 9 hours ago
$224
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Tue, Oct 21 from O'Hare Intl. to McGhee Tyson, returning Tue, Oct 28, priced at $224 found 9 hours ago
Sat, Aug 9 - Sat, Aug 16
ORD
O'Hare Intl.
TYS
McGhee Tyson
$228 Roundtrip, found 22 hours ago
$228
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Sat, Aug 9 from O'Hare Intl. to McGhee Tyson, returning Sat, Aug 16, priced at $228 found 22 hours ago
Sat, Jul 12 - Wed, Jul 16
ORD
O'Hare Intl.
TYS
McGhee Tyson
$229 Roundtrip, found 5 days ago
$229
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Jul 12 from O'Hare Intl. to McGhee Tyson, returning Wed, Jul 16, priced at $229 found 5 days ago
Fri, Jul 4 - Mon, Jul 7
ORD
O'Hare Intl.
TYS
McGhee Tyson
$238 Roundtrip, found 2 hours ago
$238
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Fri, Jul 4 from O'Hare Intl. to McGhee Tyson, returning Mon, Jul 7, priced at $238 found 2 hours ago
Tue, Oct 21 - Tue, Oct 28
ORD
O'Hare Intl.
TYS
McGhee Tyson
$244 Roundtrip, found 9 hours ago
$244
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Tue, Oct 21 from O'Hare Intl. to McGhee Tyson, returning Tue, Oct 28, priced at $244 found 9 hours ago
Tue, Oct 14 - Tue, Oct 21
ORD
O'Hare Intl.
TYS
McGhee Tyson
$249 Roundtrip, found 2 days ago
$249
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Oct 14 from O'Hare Intl. to McGhee Tyson, returning Tue, Oct 21, priced at $249 found 2 days ago
Thu, Sep 4 - Sun, Sep 7
ORD
O'Hare Intl.
TYS
McGhee Tyson
$253 Roundtrip, just found
$253
Roundtrip
just found
Select American Airlines flight, departing Thu, Sep 4 from O'Hare Intl. to McGhee Tyson, returning Sun, Sep 7, priced at $253 just found

Frequently asked questions

What route does flight number AA5341 take?
AA5341 takes numerous routes. The most frequently flown is Huntsville Intl. Airport to Charlotte-Douglas Intl. Airport (CLT), which is a direct flight. This flight takes roughly 1 hour and 41 minutes. That said, there may possibly be other flights with this number that are multi-stop.
What kind of plane is on flight number AA5341?
AA5341 is a flight number that is used on many routes. If you have a ticket on its most popular route, Huntsville Intl. Airport to Charlotte-Douglas Intl. Airport (CLT), you’ll likely be boarding the Bombardier CRJ700.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA5341 flight with Travelocity, please visit our Customer Service Portal.