American Airlines Flight AA5281 Deals & Information (2025/2026)

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American Airlines Flight 5281 Route Deals From $184

The cheapest prices found with in the last 7 days for return flights were $372 and $184 for one-way flights to Charlotte-Douglas Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Oct 16 - Tue, Oct 21
CVG
Cincinnati - Northern Kentucky Intl.
CLT
Charlotte-Douglas Intl.
$372 Roundtrip, found 5 days ago
$372
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Oct 16 from Cincinnati - Northern Kentucky Intl. to Charlotte-Douglas Intl., returning Tue, Oct 21, priced at $372 found 5 days ago
Sat, Nov 8 - Sat, Nov 15
CVG
Cincinnati - Northern Kentucky Intl.
CLT
Charlotte-Douglas Intl.
$375 Roundtrip, found 1 day ago
$375
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Nov 8 from Cincinnati - Northern Kentucky Intl. to Charlotte-Douglas Intl., returning Sat, Nov 15, priced at $375 found 1 day ago

Frequently asked questions

What route does flight number AA5281 take?
Flight number AA5281 takes about 49 minutes to fly directly from Charlotte, NC Airport (CLT-Charlotte-Douglas Intl.) to Greenville-Spartanburg Intl. Airport (GSP). Sure, there's magic in the destination, but half the fun is in the journey!
What kind of plane is on flight number AA5281?
The route for AA5281 is most commonly CLT to Greenville-Spartanburg Intl. Airport (GSP), and the Bombardier CRJ900 is the type of plane you're likely to be traveling on.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA5281 flight with Travelocity, please visit our Customer Service Portal.