American Airlines Flight 4721 Deals & Information (2025/2026)

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American Airlines Flight 4721 Route Deals From $121

The cheapest prices found with in the last 7 days for return flights were $142 and $121 for one-way flights to John F. Kennedy Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Nov 18 - Wed, Dec 17
BOS
Logan Intl.
JFK
John F. Kennedy Intl.
$142 Roundtrip, found 1 day ago
$142
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Nov 18 from Logan Intl. to John F. Kennedy Intl., returning Wed, Dec 17, priced at $142 found 1 day ago
Thu, Dec 4 - Fri, Dec 5
BOS
Logan Intl.
JFK
John F. Kennedy Intl.
$150 Roundtrip, found 15 hours ago
$150
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Thu, Dec 4 from Logan Intl. to John F. Kennedy Intl., returning Fri, Dec 5, priced at $150 found 15 hours ago
Thu, Dec 4 - Fri, Dec 5
BOS
Logan Intl.
JFK
John F. Kennedy Intl.
$180 Roundtrip, found 15 hours ago
$180
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Thu, Dec 4 from Logan Intl. to John F. Kennedy Intl., returning Fri, Dec 5, priced at $180 found 15 hours ago
Sun, Oct 26 - Sun, Nov 2
BOS
Logan Intl.
JFK
John F. Kennedy Intl.
$187 Roundtrip, found 1 day ago
$187
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Oct 26 from Logan Intl. to John F. Kennedy Intl., returning Sun, Nov 2, priced at $187 found 1 day ago

Frequently asked questions

What route does flight number AA4721 take?
AA4721 is used on multiple routes, but the most common is between BUF and Philadelphia, PA Airport (PHL-Philadelphia Intl.). If your flight is direct, you'll disembark the plane in around 1 hour and 26 minutes. Multi-stop flights can also operate under the same number, as can flights on other routes.
What kind of plane is on flight number AA4721?
AA4721 is a flight number that is used on several routes. If you have a ticket on its most popular route, Buffalo Niagara International Airport to PHL, you'll likely be on an Embraer 175.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4721 flight with Travelocity, please visit our Customer Service Portal.