American Airlines Flight 4506 Deals & Information (2025/2026)

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American Airlines Flight 4506 Route Deals From $170

The cheapest prices found with in the last 7 days for return flights were $209 and $170 for one-way flights to Columbia Metropolitan for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Feb 13 - Sun, Feb 15
LGA
LaGuardia
CAE
Columbia Metropolitan
$209 Roundtrip, found 1 day ago
$209
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Feb 13 from LaGuardia to Columbia Metropolitan, returning Sun, Feb 15, priced at $209 found 1 day ago
Tue, Nov 4 - Sat, Nov 8
LGA
LaGuardia
CAE
Columbia Metropolitan
$267 Roundtrip, found 1 day ago
$267
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Nov 4 from LaGuardia to Columbia Metropolitan, returning Sat, Nov 8, priced at $267 found 1 day ago
Fri, Oct 10 - Mon, Oct 13
LGA
LaGuardia
CAE
Columbia Metropolitan
$284 Roundtrip, found 1 day ago
$284
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Oct 10 from LaGuardia to Columbia Metropolitan, returning Mon, Oct 13, priced at $284 found 1 day ago
Sat, Oct 11 - Mon, Oct 13
LGA
LaGuardia
CAE
Columbia Metropolitan
$284 Roundtrip, found 1 day ago
$284
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Oct 11 from LaGuardia to Columbia Metropolitan, returning Mon, Oct 13, priced at $284 found 1 day ago
Fri, Feb 13 - Sun, Feb 15
LGA
LaGuardia
CAE
Columbia Metropolitan
$294 Roundtrip, found 1 day ago
$294
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Feb 13 from LaGuardia to Columbia Metropolitan, returning Sun, Feb 15, priced at $294 found 1 day ago
Tue, Nov 4 - Sat, Nov 8
LGA
LaGuardia
CAE
Columbia Metropolitan
$310 Roundtrip, found 1 day ago
$310
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Nov 4 from LaGuardia to Columbia Metropolitan, returning Sat, Nov 8, priced at $310 found 1 day ago
Wed, Oct 15 - Wed, Oct 22
LGA
LaGuardia
CAE
Columbia Metropolitan
$314 Roundtrip, found 4 days ago
$314
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Oct 15 from LaGuardia to Columbia Metropolitan, returning Wed, Oct 22, priced at $314 found 4 days ago
Sat, Oct 25 - Tue, Oct 28
LGA
LaGuardia
CAE
Columbia Metropolitan
$319 Roundtrip, found 2 days ago
$319
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Oct 25 from LaGuardia to Columbia Metropolitan, returning Tue, Oct 28, priced at $319 found 2 days ago
Tue, Nov 4 - Sat, Nov 8
LGA
LaGuardia
CAE
Columbia Metropolitan
$320 Roundtrip, found 1 day ago
$320
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Nov 4 from LaGuardia to Columbia Metropolitan, returning Sat, Nov 8, priced at $320 found 1 day ago
Wed, Oct 15 - Wed, Oct 22
LGA
LaGuardia
CAE
Columbia Metropolitan
$324 Roundtrip, found 4 days ago
$324
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Oct 15 from LaGuardia to Columbia Metropolitan, returning Wed, Oct 22, priced at $324 found 4 days ago

Frequently asked questions

What route does flight number AA4506 take?
AA4506 serves multiple routes, but the most common is between Nashville International Airport and Raleigh, NC Airport (RDU-Raleigh - Durham Intl.). If on a non-stop flight, you'll disembark the plane in roughly 1 hour and 34 minutes. Multi-stop flights can also operate under the same number, as can services on other routes.
What kind of plane is on flight number AA4506?
AA4506 is a flight number that's used on many different routes. If you're booked on its most popular route, Nashville International Airport to Raleigh–Durham Airport, chances are you'll be boarding the Embraer 175.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4506 flight with Travelocity, please visit our Customer Service Portal.