Book a hotel near Florida Keys National Marine Sanctuary, Key West
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Top hotels close to Florida Keys National Marine Sanctuary

Caribbean House
226 Petronia St Key West FL
0.29 mi from Florida Keys National Marine Sanctuary
$149 nightly
The price is $164 total per night
$164 total
Dec 9 - Dec 10
Total with taxes and fees
This bed & breakfast features free WiFi in public areas, concierge services, and self parking. Enjoy the free local cuisine breakfast each morning. A terrace, express check-in, and express check-out are also on offer.

Weatherstation Inn
57 Front St Key West FL
Free Cancellation
Reserve now, pay when you stay
0.36 mi from Florida Keys National Marine Sanctuary
$219 nightly
The price is $246 total per night
$246 total
Dec 16 - Dec 17
Total with taxes and fees
An outdoor pool, free self parking, and concierge services are featured at this bed & breakfast. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A terrace and free newspapers are also provided.

Steps from Duval, Pool on Site & Bikes Included!
Key West FL
0.38 mi from Florida Keys National Marine Sanctuary
$205 nightly
The price is $228 total per night
$228 total
Dec 10 - Dec 11
Total with taxes and fees
This apartment features an outdoor pool and a hot tub. Laundry facilities and barbecue grills are also provided.

Claude Monet Suite | Cozy Studio with Pool & Patio Access!
Key West FL
0.38 mi from Florida Keys National Marine Sanctuary
$288 nightly
The price is $317 total per night
$317 total
Dec 10 - Dec 11
Total with taxes and fees
This apartment features laundry facilities.

Coco Plum Inn
611 Whitehead Street Key West FL
0.38 mi from Florida Keys National Marine Sanctuary
$206 nightly
The price is $232 total per night
$232 total
Dec 14 - Dec 15
Total with taxes and fees
An outdoor pool is featured at this guesthouse, along with free WiFi in public areas and a terrace. Enjoy the free continental breakfast each morning. A garden, luggage storage, and concierge services are also on offer.

Lighthouse Hotel - Key West Historic Inns
902 Whitehead St Key West FL
Free Cancellation
Reserve now, pay when you stay
0.4 mi from Florida Keys National Marine Sanctuary
$284 nightly
The price is $320 total per night
$320 total
Dec 9 - Dec 10
Total with taxes and fees
This hotel features an outdoor pool and a poolside bar. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A terrace, a garden, and a picnic area are also on offer.

The Cabana Inn Key West - Adults Only
413 Applerouth Lane Key West FL
Free Cancellation
Reserve now, pay when you stay
0.42 mi from Florida Keys National Marine Sanctuary
$167 nightly
The price is $188 total per night
$188 total
Dec 17 - Dec 18
Total with taxes and fees
This guesthouse features an outdoor pool and a hot tub. Enjoy the free continental breakfast each morning. Self parking, a terrace, and a garden are also offered.

Duval House
815 Duval St Key West FL
0.48 mi from Florida Keys National Marine Sanctuary
$150 nightly
The price is $166 total per night
$166 total
Dec 9 - Dec 10
Total with taxes and fees
This bed & breakfast features a terrace, concierge services, and self parking. A garden, a picnic area, and express check-in are also on offer.

Wicker Guesthouse
913 Duval Street Key West FL
0.5 mi from Florida Keys National Marine Sanctuary
$319 nightly
The price is $359 total per night
$359 total
Dec 9 - Dec 10
Total with taxes and fees
This guesthouse features an outdoor pool and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. A terrace, a garden, and a library are also on offer.

La Concha Key West, Autograph Collection
430 Duval St Key West FL
Free Cancellation
Reserve now, pay when you stay
0.5 mi from Florida Keys National Marine Sanctuary
$259 nightly
The price is $291 total per night
$291 total
Dec 14 - Dec 15
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and valet parking. There's a poolside bar on site, and a 24-hour front desk and concierge services are also provided.

Opal Key Resort & Marina, Key West
245 Front Street Key West FL
Free Cancellation
Reserve now, pay when you stay
0.57 mi from Florida Keys National Marine Sanctuary
$284 nightly
The price is $320 total per night
$320 total
Dec 14 - Dec 15
Total with taxes and fees
A marina, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the outdoor pool and visit the 3 bars/lounges and poolside bar for drinks.

Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
Free Cancellation
0.7 mi from Florida Keys National Marine Sanctuary
$280 nightly
The price is $315 total per night
$315 total
Dec 15 - Dec 16
Total with taxes and fees
This hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling for business? Take advantage of the 24-hour business center, laundry service, and conference space.
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See all available properties in Florida Keys National Marine Sanctuary
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Florida Keys National Marine Sanctuary hotels essential information
Accommodation | 2,749 hotels |
|---|---|
Lowest Price | $164 |
Highest Price | $359 |
Popular hotels | Southernmost Beach Resort and Guesthouses, Caribbean House, La Concha Key West, Autograph Collection, Lighthouse Hotel - Key West Historic Inns, The Cabana Inn Key West - Adults Only, Weatherstation Inn, Wicker Guesthouse, Duval House, Steps from Duval, Pool on Site & Bikes Included!, Coco Plum Inn, Claude Monet Suite | Cozy Studio with Pool & Patio Access!, Opal Key Resort & Marina, Key West |
Recent Florida Keys National Marine Sanctuary hotel reviews by fellow wanderers

Wicker Guesthouse
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Everything was great! "
A verified traveler stayed at Wicker Guesthouse
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