Isla Grande Vacation Packages 2026 from $720

Isla Grande flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Decapolis Hotel Panama City

San Francisco

$720

per person

Oct 15 - Oct 19

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and free valet parking. Enjoy the outdoor pool and free buffet breakfast each morning.

Megapolis Hotel Panamá

San Francisco

Save 100% on your flight

$836

per person

Oct 15 - Oct 19

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.

Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

$807

per person

Oct 15 - Oct 19

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.

La Cuadra by Wynwood House

El Chorrillo

$909

per person

Nov 4 - Nov 11

found 1 day ago

Roundtrip flight included

Bridgetown (BGI) to Panama City (PTY)

An outdoor pool is on site and the staff is available around-the-clock at the 24-hour front desk.

Hotel Riu Plaza Panama

Bella Vista

$757

per person

Oct 15 - Oct 19

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.

Top Isla Grande hotels deals

Ordovician Beach Resort

Isla Grande Isla Grande Colon

$394 nightly

$437 total

Oct 5 - Oct 6

Total with taxes and fees

This smoke-free resort features a private beach, a full-service spa, and 2 restaurants. Relax with free beach cabanas, sun loungers, and beach umbrellas. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like full breakfast and free self parking.

On private beach

Pool

HOTEL ISLA GRANDE

Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province

$99 nightly

$109 total

Sep 25 - Sep 26

Total with taxes and fees

This hotel features a restaurant, a bar/lounge, and a beach bar. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. Free WiFi in public areas is also provided.

Breakfast included

Spa

Hotel Cocotal

La Guaira Isla Grande Provincia de Colón

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This smoke-free hotel features 20 restaurants and 20 bars/lounges. Enjoy a meal in one of the 19 coffee shops/cafes and free perks like cooked-to-order breakfast and WiFi in public areas. Wedding services are provided for your convenience.

Breakfast included

Pet friendly

Ocean View Villa with AC + Starlink + BBQ + Private Beach + Kitchen + Parking

Colón Colón

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This villa features laundry facilities.

Air conditioning

Laundry

Deluxe Beachfront 4-bedroom house in Colón Province

Colón Province Colón Province

$387 nightly

$387 total

Sep 5 - Sep 6

Total with taxes and fees

Stay at this vacation home in Isla Grande. Enjoy air conditioning. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Pet friendly

Air conditioning

Brother Sun Villas

Camino Al Faro Isla Grande

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This vacation home features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the indoor pool and conveniences like a terrace and barbecue grills.

Pool

Kitchen

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See all available properties in Isla Grande

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much are vacation packages to Isla Grande?

$720 is all you need to spend for a memorable vacation in Isla Grande. Bundle your hotel and flights into a vacation package with Travelocity and see your savings add up. With such good prices, it's never been more tempting to travel.

Where can I get the best vacation package deals for Isla Grande?

With around 400 partner airlines and 1,000,000 properties around the world, it's hard to beat Travelocity. Browse our comprehensive range and pick up the best Isla Grande vacation package. Isn't it amazing when trip planning is that easy?

Why should I purchase my Isla Grande vacation package via Travelocity?

Because you'll never roam alone if you secure your trip with us, and we offer round-the-clock support and exceptional service to boot. Add to that our Price Match Guarantee and a massive range of destinations to select from. We're here to help you have the vacation of a lifetime.

Will I save money on my Isla Grande car rental if I bundle it with a hotel or flight?

Certainly. And our Isla Grande vacation packages are the best way to do it. With only a few clicks you can save cash and time by bundling your bookings. Collect the keys to your rental car and feel the freedom of the open road. Need to fill your itinerary? Add some activities or experiences to your package and make savings on those too.