Explore top 2026 4 Star Hotels in Otay Mesa West

Name: Omni San Diego Hotel at the Ballpark
Price range: $271 total
Rating: 9.2

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Top Otay Mesa West 4 Star hotels

Hard Rock Hotel San Diego

207 5th Ave San Diego CA

$237 nightly

$274 total

Apr 5 - Apr 6

Total with taxes and fees

A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...

9/10 Wonderful! (3,424 reviews)

Freindly staff and it felt like a home away from home

Reviewed on Mar 20, 2026

Manchester Grand Hyatt San Diego

1 Market Pl San Diego CA

$236 nightly

$274 total

Apr 2 - Apr 3

Total with taxes and fees

This hotel features 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9/10 Wonderful! (2,898 reviews)

Housekeeping services were lacking. Had to ask for basic supplies on a daily basis. For example, coffee, coffee cups, toilet paper, tissues, etc. Some towels were stained and they were all worn out and needed to be replaced badly. When we arrived to our room, there was a half-full water bottle on ...

Reviewed on Mar 20, 2026

Paradise Point Resort & Spa

1404 Vacation Rd San Diego CA

$273 nightly

$314 total

Apr 5 - Apr 6

Total with taxes and fees

This smoke-free resort features a full-service spa, a marina, and 2 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...

8.8/10 Excellent! (2,463 reviews)

The amenities are great on paper but in person they are VERY old and weathered. The property is not well kept. Our room smelled like mildew. Don't be fooled by the great marketing material they have this is definitely a ZERO luxury spot.

Reviewed on Mar 20, 2026

Hyatt Regency Mission Bay Spa and Marina

1441 Quivira Rd San Diego CA

Fully refundableReserve now, pay when you stay

$245 nightly

$282 total

Apr 5 - Apr 6

Total with taxes and fees

This smoke-free hotel features a full-service spa, a marina, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...

8.4/10 Very Good! (1,604 reviews)

Rooms were clean, property was great.

Reviewed on Mar 21, 2026

Wyndham San Diego Bayside

1355 N Harbor Drive San Diego CA

Fully refundableReserve now, pay when you stay

$182 nightly

$211 total

Mar 29 - Mar 30

Total with taxes and fees

This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

8.4/10 Very Good! (6,064 reviews)

We upgraded to a harbor view room. Incredible. Steps from the embarcadero. Nice place, good location.

Reviewed on Mar 20, 2026

San Diego Marriott Gaslamp Quarter

660 K St San Diego CA

$152 nightly

$176 total

Apr 5 - Apr 6

Total with taxes and fees

A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, express ...

8.8/10 Excellent! (1,663 reviews)

Loud plumbing dripping sounds when adjacent room used their sink/toilet/shower.

Reviewed on Mar 20, 2026

Lafayette Hotel & Club

2223 El Cajon Blvd San Diego CA

Fully refundableReserve now, pay when you stay

$249 nightly

$286 total

Mar 23 - Mar 24

Total with taxes and fees

This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...

9.2/10 Wonderful! (1,534 reviews)

Stunning place especially if you’re a fan of the great gastby!..

Reviewed on Mar 20, 2026

Sheraton San Diego Resort

1380 Harbor Island Dr San Diego CA

Fully refundableReserve now, pay when you stay

$163 nightly

$188 total

Apr 1 - Apr 2

Total with taxes and fees

A marina, 5 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi ...

8.4/10 Very Good! (3,384 reviews)

The room had a broken outlet but enough for me to use else where. However, my biggest issue was the lack of privacy and the cost cutting door they provide for bathroom. With the "budget" room they have a sliding slated barn door. For the price of this room I'm disappointed in the privacy, or lack ...

Reviewed on Mar 19, 2026

Omni San Diego Hotel at the Ballpark

675 L St San Diego CA

$234 nightly

$271 total

Apr 3 - Apr 4

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9.2/10 Wonderful! (2,085 reviews)

Great experience walking distance to Petco, convention center, Starbucks, whatever you need.

Reviewed on Mar 18, 2026

San Diego Mission Bay Resort

1775 E Mission Bay Dr San Diego CA

Fully refundableReserve now, pay when you stay

$285 nightly

$328 total

Apr 5 - Apr 6

Total with taxes and fees

A full-service spa, 2 restaurants, and 5 outdoor tennis courts are all featured at this Mediterranean resort. There's fun for all ages with a children's pool ...

8.4/10 Very Good! (1,380 reviews)

We had a great experience. Kids loved the pool, us adults loved the hot tubs. Came back to nice, clean rooms every day. Tons of things to do and great views with direct access to the bay. Would absolutely stay here again.

Reviewed on Mar 21, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.