Explore the best 2025 4 Star Hotels Hotels in Mesopotamia

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Top Mesopotamia 4 Star hotels

Esplendor by Wyndham Savoy Rosario

San Lorenzo 1022, Between Sarmiento and San Martín, Rosario, Santa Fe

Free Cancellation

Reserve now, pay when you stay

$77 nightly

$77 total

Jun 8 - Jun 9

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and free perks like buffet breakfast and a shopping center shuttle.

Pool

Breakfast included

Dazzler by Wyndham Rosario

Junin 187, Rosario, Santa Fe

Free Cancellation

Reserve now, pay when you stay

$73 nightly

$73 total

Jun 8 - Jun 9

This hotel features an outdoor pool, a hot tub, and a restaurant. Enjoy the gym and free perks like full breakfast and WiFi in public areas. There's a bar/lounge on site, and a 24-hour front desk and laundry facilities are also provided.

Pool

Hot Tub

InterTower Hotel

San Jeronimo 2779, Santa Fe, Santa Fe

Free Cancellation

Reserve now, pay when you stay

$96 nightly

$96 total

Jun 9 - Jun 10

A full-service spa, an outdoor pool, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the gym and free buffet breakfast each morning.

Pool

Breakfast included

Amérian Hotel Casino Gala

Juan Domingo Perón 330 esq. Necochea, Resistencia, Chaco

Free Cancellation

Reserve now, pay when you stay

$72 nightly

$72 total

Jun 6 - Jun 7

A casino and an outdoor pool are featured at this smoke-free hotel. Enjoy a meal from the restaurant and perks like free buffet breakfast and free WiFi. Luggage storage and a safe deposit box are also provided.

Pool

Breakfast included

Puerto Norte Design Hotel

Av Luis Candido Carballo 148, Rosario, Santa Fe

Free Cancellation

Reserve now, pay when you stay

$154 nightly

$154 total

Jun 8 - Jun 9

A full-service spa, an outdoor pool, and a restaurant are all featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Enjoy the indoor pool and free buffet breakfast each morning.

Pool

Hot Tub

Pullman Rosario City Center Hotel

Av Batlle Y Ordoñez Y Bv Oroño, City Center, Rosario, Santa Fe

Free Cancellation

Reserve now, pay when you stay

$131 nightly

$131 total

Jun 8 - Jun 9

This Beaux Arts hotel features a casino, a full-service spa, and a nightclub. There's fun for all ages with a playground and an arcade/game room, and families will appreciate the onsite laundry facilities. Enjoy a meal in one of the 2 restaurants and free perks like valet parking and WiFi in public areas.

Pool

Breakfast included

Agustín 1 Apart

130 Gral. Pedro Ferré, Parana, Entre Ríos

Free Cancellation

Reserve now, pay when you stay

$63 nightly

$63 total

Jun 23 - Jun 24

This aparthotel features express check-in, a virtual front desk, and self parking. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. Express check-out is also provided.

Kitchen

Pet friendly

Hotel Solans Presidente

919 Avenue Corrientes, Rosario, Santa Fe

Free Cancellation

Reserve now, pay when you stay

$97 nightly

$97 total

Jun 17 - Jun 18

This hotel features a restaurant, a seasonal outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the a rooftop terrace and free buffet breakfast each morning.

Pool

Breakfast included

Ros Tower Hotel

Mitre 299, Rosario, Santa Fe

$119 nightly

$119 total

Jun 8 - Jun 9

A full-service spa and an outdoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, laundry service, and airport shuttle. You'll appreciate the steam room, bar/lounge, and laundry facilities.

Pool

Spa

La Alondra Casa De Huéspedes

Av. 3 De Abril 827, Corrientes, Corrientes

$162 nightly

$162 total

Jun 8 - Jun 9

This guesthouse features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Enjoy the gym and free perks like full breakfast and free self parking.

Pool

Breakfast included

Apart Hotel Ribera del Baradero

Av. Almte. Brown, 83, Baradero, Provincia de Buenos Aires

$108 nightly

$108 total

Jun 9 - Jun 10

This aparthotel's 2 outdoor pools and indoor pool are among the featured amenities. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. Self parking, a garden, and a picnic area are also offered.

Pool

Breakfast included

Apart Club San Pedro

Lucio Mansilla 7300, San Pedro, Buenos Aires Province

Get rates

This smoke-free aparthotel's private beach and marina are among the highlights. Enjoy the outdoor pool and perks like free WiFi. A poolside bar, a terrace, and a garden are also provided.

Pool

Kitchen

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Mesopotamia

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Mesopotamia 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Mesopotamia will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Mesopotamia, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Mesopotamia hotels essential information

Accommodation	452 hotels
Lowest Price	$63
Highest Price	$162
Popular hotels	Esplendor by Wyndham Savoy Rosario, Dazzler by Wyndham Rosario, InterTower Hotel, Amérian Hotel Casino Gala, Puerto Norte Design Hotel, Pullman Rosario City Center Hotel, Agustín 1 Apart, Hotel Solans Presidente, Ros Tower Hotel, La Alondra Casa De Huéspedes, Apart Hotel Ribera del Baradero, Apart Club San Pedro