Explore top 2025 4 Star Hotels in Clayton

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Top Clayton 4 Star hotels

JW Marriott Indianapolis

JW Marriott Indianapolis

4 out of 5
10 S West Street Indianapolis IN
Fully refundableReserve now, pay when you stay
$178 nightly
The price is $209 total per night from Nov 23 to Nov 24
$209 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9.2/10 Wonderful! (1,320 reviews)
yes

Reviewed on Nov 10, 2025

Opens in a new windowJW Marriott Indianapolis
Bottleworks Hotel

Bottleworks Hotel

4.5 out of 5
850 Massachusetts Avenue Indianapolis IN
$179 nightly
The price is $211 total per night from Nov 23 to Nov 24
$211 total
Nov 23 - Nov 24
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the steam room and perks like free WiFi. A bar/lounge, a 24-hour ...
9.8/10 Exceptional! (1,662 reviews)
A truly wonderful stay from the time I pulled up to the valet until the valet pulled up my car at checkout. Staff were cheerful and friendly. Room well appointed and spotless. All public areas, especially the extra wide hallways, had a charming vibe with interesting photos and benches reminiscent ...

Reviewed on Nov 12, 2025

Opens in a new windowBottleworks Hotel
Omni Severin Hotel

Omni Severin Hotel

4 out of 5
40 West Jackson Place Indianapolis IN
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $197 total per night from Nov 30 to Dec 1
$197 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9.2/10 Wonderful! (727 reviews)
Room was great as well as the gym.

Reviewed on Nov 10, 2025

Opens in a new windowOmni Severin Hotel
Marriott Indianapolis Downtown

Marriott Indianapolis Downtown

4 out of 5
350 W Maryland St Indianapolis IN
Fully refundableReserve now, pay when you stay
$170 nightly
The price is $200 total per night from Nov 23 to Nov 24
$200 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features 2 bars/lounges and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A restaurant, ...
9/10 Wonderful! (1,005 reviews)
Everything about this hotel is fantastic!

Reviewed on Nov 10, 2025

Opens in a new windowMarriott Indianapolis Downtown
Sheraton Indianapolis City Centre Hotel

Sheraton Indianapolis City Centre Hotel

4 out of 5
31 W Ohio St Indianapolis IN
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $109 total per night from Nov 23 to Nov 24
$109 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.2/10 Very Good! (1,001 reviews)
Very nice pool and wonderful staff.

Reviewed on Oct 27, 2025

Opens in a new windowSheraton Indianapolis City Centre Hotel
Hyatt Regency Indianapolis

Hyatt Regency Indianapolis

4 out of 5
One South Capitol Avenue Indianapolis IN
Fully refundableReserve now, pay when you stay
$150 nightly
The price is $177 total per night from Nov 30 to Dec 1
$177 total
Nov 30 - Dec 1
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
8.8/10 Excellent! (1,002 reviews)
The door of the standing shower would not seal properly - or did not have a rubber stopper, which inadvertently caused a lot of water to spill out of the shower onto the floor; Apart from this minor annoyance, the hotel was good and I enjoyed my stay.

Reviewed on Nov 10, 2025

Opens in a new windowHyatt Regency Indianapolis
Hilton Indianapolis Hotel & Suites

Hilton Indianapolis Hotel & Suites

4 out of 5
120 W Market St Indianapolis IN
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $173 total per night from Nov 26 to Nov 27
$173 total
Nov 26 - Nov 27
Total with taxes and fees
This traditional hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express ...
8.4/10 Very Good! (1,002 reviews)
Verry good

Reviewed on Nov 10, 2025

Opens in a new windowHilton Indianapolis Hotel & Suites
The Alexander

The Alexander

4 out of 5
333 S Delaware St Indianapolis IN
Fully refundableReserve now, pay when you stay
$237 nightly
The price is $278 total per night from Nov 22 to Nov 23
$278 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.8/10 Excellent! (1,001 reviews)
Yes. Very friendly customer service.

Reviewed on Nov 12, 2025

Opens in a new windowThe Alexander
InterContinental Indianapolis by IHG

InterContinental Indianapolis by IHG

4 out of 5
17 West Market Street Indianapolis IN
$176 nightly
The price is $207 total per night from Nov 29 to Nov 30
$207 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. WiFi in public areas is free. Valet parking, dry cleaning, and luggage storage are also ...
9.4/10 Exceptional! (85 reviews)
Clean, comfortable room and friendly staff. I would definitely stay there again.

Reviewed on Nov 9, 2025

Opens in a new windowInterContinental Indianapolis by IHG
The Westin Indianapolis

The Westin Indianapolis

4 out of 5
241 W Washington Street, Indianapolis, IN
Fully refundableReserve now, pay when you stay
$146 nightly
The price is $172 total per night from Nov 23 to Nov 24
$172 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
8.6/10 Excellent! (1,000 reviews)
Beautiful hotel and I greatly appreciated the free pet stay.

Reviewed on Nov 9, 2025

Opens in a new windowThe Westin Indianapolis
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4 Star Hotels Clayton

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Clayton 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Clayton will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Clayton, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Clayton hotel reviews by fellow wanderers