Explore top 2026 4 Star Hotels in Clayton
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Top Clayton 4 Star hotels
Bottleworks Hotel
850 Massachusetts Avenue Indianapolis IN
Fully refundableReserve now, pay when you stay
$188 nightly
The price is $221 total per night from Apr 19 to Apr 20
$221 total
Apr 19 - Apr 20
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the steam room and perks like free WiFi. A bar/lounge, a 24-hour ...
9.8/10 Exceptional! (1,848 reviews)
From the moment you arrive and look at the very cool structure that this old Cole bottling plant was and how it’s been transformed to a very cool and beautiful hotel. The entire staff was kind and attentive. The lobby has a pool table that seems to be used quite a lot by guests. There is nice bar ...
Reviewed on Apr 8, 2026
Omni Severin Hotel
40 West Jackson Place Indianapolis IN
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $196 total per night from Apr 12 to Apr 13
$196 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9.4/10 Exceptional! (911 reviews)
Room was fine, but a little run down. Water stain on the lower part of our drapes and a few broken or damaged pieces of furniture in the room. The biggest let down however was the closed pool due to rebalancing of chemicals with no notice. We only live a couple hours away so the pool was part of ...
Reviewed on Apr 6, 2026
JW Marriott Indianapolis
10 S West Street Indianapolis IN
Fully refundableReserve now, pay when you stay
$214 nightly
The price is $251 total per night from Apr 26 to Apr 27
$251 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9.4/10 Exceptional! (1,345 reviews)
Great location, great room, and excellent breakfast at Velocity in the Marriott.
Reviewed on Mar 28, 2026
Marriott Indianapolis Downtown
350 W Maryland St Indianapolis IN
Fully refundableReserve now, pay when you stay
$196 nightly
The price is $230 total per night from Apr 26 to Apr 27
$230 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features 2 bars/lounges and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A restaurant, ...
9.2/10 Wonderful! (1,008 reviews)
The room was fabulous, food not so much. Staff were friendly and helpful. There were very few options for room service and what they did offer was not that great.
Reviewed on Mar 30, 2026
Hyatt Regency Indianapolis
One South Capitol Avenue Indianapolis IN
Fully refundableReserve now, pay when you stay
$153 nightly
The price is $180 total per night from Apr 30 to May 1
$180 total
Apr 30 - May 1
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
9/10 Wonderful! (1,004 reviews)
Came for the games and honestly rooms were very dirty, for the reviews I read i expected way better. Def needs Renovated Shower poor, leaks, carpet filthy Almost hard to sleep on bed seeing the condition of room
Reviewed on Apr 7, 2026
Hilton Indianapolis Hotel & Suites
120 W Market St Indianapolis IN
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $173 total per night from Apr 19 to Apr 20
$173 total
Apr 19 - Apr 20
Total with taxes and fees
This traditional hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express ...
8.6/10 Excellent! (1,005 reviews)
The weight room and pool were very clean and the hours were very reasonable.
Reviewed on Apr 1, 2026
Sheraton Indianapolis City Centre Hotel
31 W Ohio St Indianapolis IN
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $158 total per night from Apr 12 to Apr 13
$158 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.4/10 Very Good! (1,000 reviews)
Incredibly loud room by the elevator. Very loud noise from the street and l was on the 10th floor.
Reviewed on Mar 21, 2026
The Westin Indianapolis
241 W Washington Street Indianapolis IN
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $204 total per night from Apr 25 to Apr 26
$204 total
Apr 25 - Apr 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
InterContinental Indianapolis by IHG
17 West Market Street Indianapolis IN
Fully refundable
$196 nightly
The price is $230 total per night from Apr 19 to Apr 20
$230 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. WiFi in public areas is free. Valet parking, dry cleaning, and luggage storage are also ...
9.6/10 Exceptional! (132 reviews)
The room was outstanding! Very large, very clean. Nicely cooled and the furniture and ammenities were on point. I'm a general contractor so I can appreciate fine construction. The showers was large with a rain fall shower head. Everything was top notch. I wish all hotels were like this. I can’t rave ...
Reviewed on Apr 3, 2026
Hotel Indy, Indianapolis, a Tribute Portfolio Hotel
141 E WASHINGTON STREET Indianapolis IN
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $196 total per night from Apr 26 to Apr 27
$196 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. WiFi in public areas is free. Valet parking is offered and the front desk is staffed ...
9.2/10 Wonderful! (376 reviews)
It was welcoming and people were friendly. I would say I would stay there again. Did not get to experience breakfast or the main bar. However, the sixth floor club was pretty fun with a good DJ and good drinks, but the drinks were pricey so beware. The room was extremely clean and the bed was great. ...
Reviewed on Mar 28, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels Clayton
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Clayton 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Clayton will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Clayton, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Clayton hotel reviews by fellow wanderers
Bottleworks Hotel
5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"From the moment you arrive and look at the very cool structure that this old Cole bottling plant was and how it’s been transformed to a very cool and beautiful hotel. The entire staff was kind and attentive. The lobby has a pool table that seems to be used quite a lot by guests. There is nice bar next to the lobby that offers great cocktails. We were on the 2nd floor of a 4 floor building with the widest and longest corridors that are beautifully designed with cool discoveries every 10ft. The rooms are really big with huge windows, a seating area, great local snacks, a nice bed with great sheets, and decor that is original and fits the vintage Industrial vibe. It’s the best place to call him when in Indianapolis and it’s an a trendy neighborhood with a food hall across the street that has awesome options, restaurants, coffee shops, and so much more. We loved it and we will be back!"
A verified traveler stayed at Bottleworks Hotel
