Explore 12 Luxury Hotels in Wytheville

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Best Luxury Hotels in Wytheville

The Bolling Wilson Hotel

The Bolling Wilson Hotel

170 East Main Street Wytheville VA
Fully refundableReserve now, pay when you stay
$181 nightly
The price is $208 total per night from Dec 7 to Dec 8
$208 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features a restaurant, a rooftop terrace, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet ...
9.4/10 Exceptional! (1,002 reviews)
"The hotel was very nice! We had a great time and breakfast was delicious. We took our EMF reader and had tons of activity! The town was cute and felt safe walking around. Would stay here again."

Reviewed on Nov 14, 2026

Opens in a new windowThe Bolling Wilson Hotel
Red Roof Inn Wytheville

Red Roof Inn Wytheville

220 Lithia Rd Wytheville VA
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $71 total per night from Nov 18 to Nov 19
$71 total
Nov 18 - Nov 19
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Multilingual staff can provide around-the-clock assistance and laundry ...
8.2/10 Very Good! (761 reviews)
"Although the property is older, the efforts to update and modernize the rooms certainly did not go unnoticed! The new light fixtures with built-in power outlets and USB charging ports were a thoughtful and convenient upgrade. The updated sink and mirror were also nice touches, and both the bed and ..."

Reviewed on Nov 13, 2026

Opens in a new windowRed Roof Inn Wytheville
Quality Inn Wytheville

Quality Inn Wytheville

1900 E Main St Wytheville VA
Fully refundable
$64 nightly
The price is $74 total per night from Nov 29 to Nov 30
$74 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
7.6/10 Good! (300 reviews)
"Breakfast was not as great as expected. The room was a bit noisy, but clean, and staff was very nice and located central to our stay."

Reviewed on Nov 12, 2026

Opens in a new windowQuality Inn Wytheville
Travel Lite Motel

Travel Lite Motel

655 East Main Street Wytheville VA
$66 nightly
The price is $76 total per night from Nov 27 to Nov 28
$76 total
Nov 27 - Nov 28
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
7.2/10 Good! (186 reviews)
"Strong smells, wooden floor feels like walking on a water bed, ac blows hot air, tv is very tiny and can't hookyou game system up, funiture sticky with stains, beds don't look refreshed, door had openings at the bottom for bugs from outside to come in, dont book in whytheville, if you do pay in person, ..."

Reviewed on Oct 4, 2026

Opens in a new windowTravel Lite Motel
Edyn Hotel By Townhouse Wytheville US 52

Edyn Hotel By Townhouse Wytheville US 52

280 Lithia Rd Wytheville VA
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $68 total per night from Nov 16 to Nov 17
$68 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
6.8/10 (321 reviews)
"The place was not fancy, but very comfortable, clean and priced fairly. The staff was very accommodating and I enjoyed my stay."

Reviewed on Nov 5, 2026

Opens in a new windowEdyn Hotel By Townhouse Wytheville US 52
Ramada by Wyndham Wytheville

Ramada by Wyndham Wytheville

955 Peppers Ferry Rd Wytheville VA
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $69 total per night from Nov 21 to Nov 22
$69 total
Nov 21 - Nov 22
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowRamada by Wyndham Wytheville
Days Inn by Wyndham Wytheville

Days Inn by Wyndham Wytheville

150 Malin Dr, I-81 and I-77 Exit 73 Wytheville VA
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $69 total per night from Dec 6 to Dec 7
$69 total
Dec 6 - Dec 7
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Opens in a new windowDays Inn by Wyndham Wytheville
Americas Best Value Inn Wytheville

Americas Best Value Inn Wytheville

705 Chapman Road Wytheville VA
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $83 total per night from Nov 16 to Nov 17
$83 total
Nov 16 - Nov 17
Total with taxes and fees
Free self parking is available and the motel's front desk is staffed around-the-clock. WiFi in public areas is free. Express check-in and express check-out are ...
Opens in a new windowAmericas Best Value Inn Wytheville
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Wytheville Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Wytheville luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Wytheville to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Wytheville will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Wytheville, and plan your next opulent escape.


Wytheville hotels essential information

Accommodation
407 hotels
Lowest Price
$68
Highest Price
$208
Popular hotels
Ramada by Wyndham Wytheville, Travel Lite Motel, Quality Inn Wytheville, Red Roof Inn Wytheville, Edyn Hotel By Townhouse Wytheville US 52, Days Inn by Wyndham Wytheville, Americas Best Value Inn Wytheville, The Bolling Wilson Hotel

Popular Luxury Stays in Wytheville

Recent Wytheville Hotel Reviews By Fellow Wanderers