Explore 31 Luxury Hotels in South Region

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Best Luxury Hotels in South Region

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

Rodovia Br 469 Km 32 Foz do Iguaçu PR
$855 nightly
The price is $909 total per night from Dec 4 to Dec 5
$909 total
Dec 4 - Dec 5
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. There's fun for all ages with a free kid's club and a children's ...
10/10 Exceptional! (1,005 reviews)
"The hotel is beautiful and the service was outstanding. The hotel is located across the street from the Falls on the Brazil side and the view is amazing!"

Reviewed on Nov 1, 2026

Opens in a new windowHotel das Cataratas, A Belmond Hotel, Iguassu Falls
Nomaa Hotel

Nomaa Hotel

Rua Gutemberg,168 Curitiba PR
$203 nightly
The price is $216 total per night from Nov 22 to Nov 23
$216 total
Nov 22 - Nov 23
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
9.8/10 Exceptional! (561 reviews)
"The breakfast was perfect - it had both made to order options and a small but varied selection of buffet items - and the restaurant and property overall were beautiful and luxe. The bed is comfortable, the space is clean and modern, and the hotel had wonderful attention to detail. Highly recommended ..."

Reviewed on Oct 7, 2026

Opens in a new windowNomaa Hotel
Iguazú Grand Hotel

Iguazú Grand Hotel

Route 12 Km 1640 Puerto Iguazú Misiones
Fully refundableReserve now, pay when you stay
$267 nightly
The price is $276 total per night from Dec 5 to Dec 6
$276 total
Dec 5 - Dec 6
This smoke-free hotel features a casino, a full-service spa, and a nightclub. There's fun for all ages with a free kid's club and mini golf, and in-room childcare ...
9.2/10 Wonderful! (700 reviews)
"The property was good and most folks were welcoming and helpful the WiFi was strange and one of my laptop couldn’t linkup and one of the staff refused to make us an extra key"

Reviewed on Oct 26, 2026

Opens in a new windowIguazú Grand Hotel
Novotel Florianópolis

Novotel Florianópolis

Av. Rubens Arruda Ramos, 2034 Florianópolis SC
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $112 total per night from Nov 22 to Nov 23
$112 total
Nov 22 - Nov 23
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,000 reviews)
"too outdated rooms are terrible tvs old not recommended"

Reviewed on Nov 2, 2026

Opens in a new windowNovotel Florianópolis
Felissimo Exclusive Hotel

Felissimo Exclusive Hotel

201 Alles Blaun Balneário Camboriú SC
$302 nightly
The price is $310 total per night from Dec 2 to Dec 3
$310 total
Dec 2 - Dec 3
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the hot tub and free perks like buffet breakfast and free self parking. You'll appreciate ...
9/10 Wonderful! (76 reviews)
"Excellent hotel with great professionals. We love it"

Reviewed on Jan 17, 2026

Opens in a new windowFelissimo Exclusive Hotel
Spa do Vinho Hotel & Condomínio Vitivinícola

Spa do Vinho Hotel & Condomínio Vitivinícola

Rod. RS 444, KM 21 Bento Gonçalves RS
Fully refundableReserve now, pay when you stay
$303 nightly
The price is $313 total per night from Nov 8 to Nov 9
$313 total
Nov 8 - Nov 9
Total with taxes and fees
A full-service spa, 4 restaurants, and A 24-hour gym are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free ...
9/10 Wonderful! (1,003 reviews)
"Las instalaciones me parecieron un poco descuidadas, el personal muy amable y la comida tanto del desayuno como de la cena muy buena"

Reviewed on Sep 3, 2026

Opens in a new windowSpa do Vinho Hotel & Condomínio Vitivinícola
Gran Melia Iguazú

Gran Melia Iguazú

Parque Nacional Iguazu Puerto Iguazú Misiones
Fully refundableReserve now, pay when you stay
$711 nightly
The price is $720 total per night from Nov 11 to Nov 12
$720 total
Nov 11 - Nov 12
A full-service spa, 3 restaurants, and 2 outdoor pools are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free ...
Opens in a new windowGran Melia Iguazú
Infinity Blue Resort & Spa

Infinity Blue Resort & Spa

Avenida Rui Barbosa 1000 Balneário Camboriú SC
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this luxury hotel. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
Opens in a new windowInfinity Blue Resort & Spa
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5 star hotels in South Region

South Region Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the South Region luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in South Region to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in South Region will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in South Region, and plan your next opulent escape.


South Region hotels essential information

Accommodation
12,971 hotels
Lowest Price
$53
Highest Price
$909
Popular hotels
Hotel das Cataratas, A Belmond Hotel, Iguassu Falls, Iguazú Grand Hotel, Gran Melia Iguazú, Novotel Florianópolis, Felissimo Exclusive Hotel, Spa do Vinho Hotel & Condomínio Vitivinícola, Infinity Blue Resort & Spa, Nomaa Hotel

Popular Luxury Stays in South Region

Recent South Region Hotel Reviews By Fellow Wanderers