Deals on vacations and trips to San Francisco

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San Francisco flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Tocumen Airport
Price was $1,291, price is now $838 per person
$838
per person
Jan 21 - Jan 26
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
This smoke-free resort features a casino, 2 indoor tennis courts, and a restaurant. Bring the family and enjoy the children's pool, playground, and kid-friendly dining. Enjoy the outdoor pool and free perks like full breakfast and valet parking.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $1,702, price is now $943 per person
$943
per person
Jan 21 - Jan 26
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

3.5 out of 5
Casco Viejo
Price was $2,805, price is now $1,599 per person
$1,599
per person
Jan 16 - Jan 21
found 23 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
Free WiFi in public areas is available at this apartment. Take advantage of the self parking.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was $3,176, price is now $1,974 per person
$1,974
per person
Jan 19 - Jan 25
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Panama City (PTY)
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,268, price is now $906 per person
$906
per person
Jan 21 - Jan 26
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.

Top San Francisco hotels deals

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
$119 nightly
The price is $131 total per night
$131 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.
Pool
Breakfast included
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Free Cancellation
Reserve now, pay when you stay
$151 nightly
The price is $166 total per night
$166 total
Nov 17 - Nov 18
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.
Pool
Hot Tub
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$111 nightly
The price is $123 total per night
$123 total
Dec 11 - Dec 12
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and free valet parking. Enjoy the outdoor pool and free buffet breakfast each morning.
Pool
Breakfast included
Aloft by Marriott Panama

Aloft by Marriott Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$131 nightly
The price is $144 total per night
$144 total
Nov 21 - Nov 22
Total with taxes and fees
A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the outdoor pool and perks like free self parking.
Pool
Pet friendly
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$150 nightly
The price is $165 total per night
$165 total
Nov 22 - Nov 23
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and perks like free self parking.
Pool
Spa
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$131 nightly
The price is $144 total per night
$144 total
Nov 28 - Nov 29
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the gym and perks like free self parking.
Pool
Pet friendly
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular San Francisco attractions

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
See properties

Frequently asked questions

How much are vacation packages to San Francisco?
$838 is all you need to spend for an unforgettable escape in San Francisco. Bundle your hotel and flights into a Travelocity package and watch all the savings pile up. With these kinds of prices, there's never been a better time to travel.
Where can I get the best vacation package deals for San Francisco?
It's hard to look past Travelocity when it comes to piecing together your San Francisco package deal. There are as many as 400 partner airlines and 1,000,000 worldwide properties to choose from. Reserve your trip now and get ready to cross another amazing place off your must-visit list.
Why should I book my San Francisco vacation bundle via Travelocity?
From our 24/7 customer care to our range of incredible destinations, we're dedicated to fulfilling your travel desires. All you need to do is click and book — our Price Match Guarantee will ensure you lock in the best deal.
Can I save on my San Francisco car rental if I combine it with a hotel or flight?
Sure can — and booking one of our San Francisco vacation packages is the best way to go about this. Bundle any combination of a car, hotel, flight and experience and score serious discounts. The more you book, the more you'll save. There are so many famous sights in San Francisco to put on your bucket list, including Gatun Locks (35 mi from San Francisco). Nothing tops exploring places like this with the freedom of your own wheels.
What is there to do in San Francisco?
Multicentro Panama and Panama Canal Murals are loved by tourists and locals alike. Tick these places off your San Francisco itinerary and see what the hype is about.

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A bridge over a body of water with several boats.
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A cityscape with a prominent twisted skyscraper in the center, surrounded by various other buildings and a distant mountain range.
A beach with a large driftwood piece, calm water, and a few people in the distance.