
Deals on vacations and trips to San Cosme y Damian
Save when you book San Cosme y Damian package deals

San Cosme y Damian flight + hotel vacation packages
Price found within the past 48 hours. Click for updated prices.

Santa Fe Station Hotel & Casino
Centennial Hills
Save 100% on your flight
Price was $369, price is now $196 per person
$196
per person
Apr 1 - Apr 5
found 1 day ago
Roundtrip flight included
Denver (DEN) to Las Vegas (LAS)
A casino, 5 restaurants, and a 24-hour gym are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 5 bars/lounges and enjoy perks like free self parking.

The Deuce's Wild at Signature Hotel
Price was $825, price is now $299 per person
$299
per person
May 2 - May 5
found 1 day ago
Roundtrip flight included
Denver (DEN) to Las Vegas (LAS)
This aparthotel's 3 outdoor pools and 24-hour gym are among the featured amenities. Guests will appreciate free perks like valet parking and WiFi in public areas. A business center, a terrace, and luggage storage are also on offer.

W South Beach
South Beach
Price was $6,636, price is now $2,841 per person
$2,841
per person
May 1 - May 4
found 1 day ago
Roundtrip flight included
Dallas (DAL) to Miami (MIA)
A full-service spa, 2 outdoor pools, and a 24-hour gym are all featured at this luxury hotel. Relax with beach cabanas, sun loungers, and beach umbrellas. Traveling on business? Take advantage of the 24-hour business center, express check-in, and valet parking.

Westgate Flamingo Bay Resort
Spring Valley
Price was $916, price is now $396 per person
$396
per person
Apr 1 - Apr 5
found 1 day ago
Roundtrip flight included
Denver (DEN) to Las Vegas (LAS)
This hotel features an outdoor pool and a gym. Enjoy the hot tub and perks like free self parking and free WiFi. A business center, a terrace, and a grocery/convenience store are also on offer.

Creekside Inn
Price was $1,901, price is now $951 per person
$951
per person
Apr 9 - Apr 15
found 1 day ago
Roundtrip non-stop flight included
Dallas (DAL) to Miami (MIA)
This smoke-free motel's marina and 2 outdoor pools are some of the highlights. Guests will appreciate free perks like free self parking and WiFi in public areas. A picnic area and barbecue grills are also provided.
Top San Cosme y Damian hotels deals

Carnaval Hotel Casino
Av. Irrazabal, 750 Encarnacion
Free Cancellation
Reserve now, pay when you stay
$68 nightly
The price is $74 total per night
$74 total
Mar 1 - Mar 2
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and a restaurant. Enjoy the outdoor pool and free perks like buffet breakfast and free self parking. You'll appreciate the indoor pool, bar/lounge, and laundry facilities.
Pool
Hot Tub

Sun Hotel
Encarnacion Itapúa
This hotel features a gym and a rooftop terrace. Traveling on business? Take advantage of the free WiFi in public areas and airport shuttle. Enjoy the steam room and free perks like full breakfast and valet parking.
Breakfast included
Parking included

Hotel Luxsur
Jorge Memmel 661 Encarnacion
Free Cancellation
Reserve now, pay when you stay
$61 nightly
The price is $68 total per night
$68 total
Mar 9 - Mar 10
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Enjoy the a rooftop terrace and free perks like buffet breakfast and free self parking. Enjoy the sauna and unwind at the bar/lounge and poolside bar.
Pool
Breakfast included

Awa Resort Hotel
Ruta 1 Km 367, Calles Tajy y Naranjal Encarnacion
A full-service spa, 2 outdoor tennis courts, and an outdoor pool are all featured at this smoke-free resort. There's fun for all ages with a children's pool and a playground, and free supervised childcare is an added bonus. Enjoy a meal from the restaurant and perks like free buffet breakfast and free self parking.
Pool
Breakfast included

Alula Hotel Encarnacion
1848 Gral Aquino Encarnación Itapúa
Free Cancellation
Reserve now, pay when you stay
$103 nightly
The price is $113 total per night
$113 total
Mar 19 - Mar 20
Total with taxes and fees
A gym is featured at this hotel, along with free WiFi in public areas. Enjoy the free continental breakfast each morning. Staff at the 24-hour front desk can provide around-the-clock assistance.
Breakfast included
Spa

Savoy Hotel Encarnación
Avda. Costanera Padre Bolik 999 Encarnacion Itapua
Free Cancellation
Reserve now, pay when you stay
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like continental breakfast and free self parking.
Pool
Breakfast included
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See all available properties in Itapúa Department
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Guarani Jesuit Ruins of San Cosme and San Damián
Find out about the history of San Cosme y Damian when you take a trip to Guarani Jesuit Ruins of San Cosme and San Damián. Take in the museums while you're in the area.
Buenaventura Suarez Planetarium
You can spend time browsing the exhibits at Buenaventura Suarez Planetarium during your travels in San Cosme y Damian. Take in the museums while you're in the area.
Frequently asked questions
Photos of local treasures
Browse San Cosme y Damian vacation photos for more inspiration
