Explore 2 Luxury Hotels in Panajachel

Name: Regis Hotel & Spa
Price range: $88 total
Rating: 8.8

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Best Luxury Hotels in Panajachel

Hotel Atitlán

Finca San Buenaventura Panajachel Solola

Fully refundableReserve now, pay when you stay

$244 nightly

$297 total

Sep 28 - Sep 29

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the hot tub and perks like free WiFi. A garden, a snack bar/deli, and a computer station ...

9.2/10 Wonderful! (893 reviews)

"Staff were very helpful, though not as knowledgable as one would’ve hoped when asking for the tours"

Reviewed on Sep 25, 2026

Regis Hotel & Spa

3a avenida 3-47 zona 2 Panajachel Solola

Fully refundableReserve now, pay when you stay

$70 nightly

$88 total

Oct 12 - Oct 13

Total with taxes and fees

This smoke-free hotel features a full-service spa, hot springs, and a restaurant. Family-friendly amenities include a playground and in-room childcare. Enjoy ...

8.8/10 Excellent! (724 reviews)

"I been here before...its just a great place"

Reviewed on Sep 24, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

5 star hotels in Panajachel

Kula Maya Boutique Hotel & Spa

San Marcos La Laguna Sololá, Barrio 3 San Marcos La Laguna Sololá

$155 nightly

$189 total

Oct 27 - Oct 28

Total with taxes and fees

9.4/10 Exceptional! (176 reviews)

Panajachel Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Panajachel luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Panajachel to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Panajachel will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Panajachel, and plan your next opulent escape.