Deals on vacations and trips to Mesopotamia

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Mesopotamia flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Istion Club Hotel & Spa

Istion Club Hotel & Spa

5 out of 5
Save 100% on your flight
per person
Sep 19 - Sep 23
found 4 hours ago
Roundtrip flight included
Bucharest (OTP) to Thessaloniki (SKG)
A full-service spa, 2 outdoor pools, and a gym are all featured at this luxury hotel. Relax with sun loungers and beach umbrellas, and cool off with a drink at the beachside bar. Enjoy a meal from the restaurant and perks like free buffet breakfast and free self parking.
Domes Noruz Kassandra - Adults Only, Halkidiki

Domes Noruz Kassandra - Adults Only, Halkidiki

5 out of 5
Save 100% on your flight
per person
Sep 19 - Sep 23
found 4 hours ago
Roundtrip flight included
Bucharest (OTP) to Thessaloniki (SKG)
A full-service spa, 2 restaurants, and 2 outdoor pools are all featured at this luxury hotel. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Porto Carras Meliton

Porto Carras Meliton

5 out of 5
Save 100% on your flight
per person
Sep 19 - Sep 23
found 4 hours ago
Roundtrip flight included
Bucharest (OTP) to Thessaloniki (SKG)
This luxury hotel features an attached winery, a casino, and a full-service spa. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. There's fun for all ages with a free kid's club and a bowling alley, and families will appreciate the onsite laundry facilities.
Avaton Luxury Beach Resort - Relais & Chateaux

Avaton Luxury Beach Resort - Relais & Chateaux

5 out of 5
per person
Sep 19 - Sep 24
found 1 day ago
Roundtrip non-stop flight included
Tel Aviv (TLV) to Thessaloniki (SKG)
This hotel features a restaurant, a bar/lounge, and a beach bar. Dine at the beachfront restaurant and relax with beach umbrellas. There's fun for all ages with a children's club and a playground, and families will appreciate the onsite laundry facilities.
Mirabilia Boutique Hotel

Mirabilia Boutique Hotel

3 out of 5
per person
Sep 19 - Sep 24
found 1 day ago
Roundtrip non-stop flight included
Tel Aviv (TLV) to Thessaloniki (SKG)
This hotel features free WiFi in public areas, barbecue grills, and free self parking. Enjoy the free buffet breakfast each morning. A terrace, a garden, and a picnic area are also on offer.

Top Mesopotamia hotels deals

To Spiti tis Sofias

To Spiti tis Sofias

Mesopotamia, Kastoria, Western Macedonia
Free Cancellation
Reserve now, pay when you stay
$66 nightly
The price is $77 total per night
$77 total
Aug 21 - Aug 22
Total includes taxes and fees
This guesthouse doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, a lobby fireplace, and a communal living room are also on offer.
Parking included
Free WiFi
Limneon Resort & Spa

Limneon Resort & Spa

4 out of 5
4th km National Road Kastoria Athens, Kastoria
$95 nightly
The price is $120 total per night
$120 total
Sep 1 - Sep 2
Total includes taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference center. Enjoy a meal in one of the 3 coffee shops/cafes and perks like free buffet breakfast and free self parking.
Pool
Breakfast included
Hotel Anastassiou

Hotel Anastassiou

2 out of 5
1st km Highway Kastoria-Athens, Kastoria, Western Macedonia
$46 nightly
The price is $55 total per night
$55 total
Aug 9 - Aug 10
Total includes taxes and fees
Ski-in/ski-out access and a restaurant are featured at this smoke-free hotel. Enjoy the ski shuttle and onsite ski storage. Unwind with a drink at the bar/lounge and enjoy perks like free valet parking and a free airport shuttle.
Free airport shuttle
Parking included
Esperos Palace Luxury & Spa Hotel

Esperos Palace Luxury & Spa Hotel

4 out of 5
Chloe Area, Kastoria, Western Macedonia
Free Cancellation
Reserve now, pay when you stay
$105 nightly
The price is $131 total per night
$131 total
Aug 19 - Aug 20
Total includes taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Hot Tub
Calma Hotel & Spa

Calma Hotel & Spa

4 out of 5
3rd km Kastoria, Vitsi, Kastoria
Get rates
A full-service spa and a gym are featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Enjoy the seasonal outdoor pool and free perks like buffet breakfast and free self parking.
Pool
Breakfast included
Chloe Hotel

Chloe Hotel

3 out of 5
Antheon & Giasemion, Kastoria, Western Macedonia
Free Cancellation
Reserve now, pay when you stay
$102 nightly
The price is $122 total per night
$122 total
Aug 19 - Aug 20
Total includes taxes and fees
This Mediterranean hotel features ski-in/ski-out access, an attached winery, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Enjoy the outdoor tennis court and free perks like buffet breakfast and free self parking.
Breakfast included
Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Kastoria Lake

5/5(2 reviews)

Commune with nature and explore the great outdoors at Kastoria Lake during your travels in Kastoria. While you're in the area, stroll along the lakeside.

Kastoria Lake

Holy Monastery of Panagias Mauriotissas

Learn about the local history of Kastoria when you take a trip to Holy Monastery of Panagias Mauriotissas. While you're in the area, stroll along the lakeside.

Holy Monastery of Panagias Mauriotissas

Dragon's Lair

Explore the great outdoors at Dragon's Lair, a lovely green space in Kastoria. While you're in the area, stroll along the lakeside.

Dragon's Lair

Frequently asked questions

How much are vacation packages to Mesopotamia?
Travelocity offers great package deals to Mesopotamia, including hotels and flights, starting at just $606. With all the cash you save, you could book some cool tours or maybe even tack on a few extra days to your adventure.
Where can I get the best vacation package deals for Mesopotamia?
There are awesome Mesopotamia package deals to be snapped up with Travelocity. Did you know we partner with 400 airlines and 1,000,000 properties in all corners of the globe? Keep this in mind the next time you're ready to tick another place off your bucket list.
Why should I book my Mesopotamia vacation package with Travelocity?
Because you'll never wander alone if you book your vacation with us, and we offer round-the-clock support and exceptional service to boot. Add to that our Price Match Guarantee and a massive range of experiences and destinations to select from. It's our job to help you jet off on the vacation of a lifetime.
Will I save money on my Mesopotamia car rental if I combine it with hotels and flights?
Combining your car, hotel and flight into a Mesopotamia vacation package is the easiest way to land the best prices. Plus, having your own wheels gives you total freedom to find your way to all those big-name sights you can't wait to explore. Located 95 mi from Mesopotamia, White Tower of Thessaloniki is one attraction that should feature on your itinerary. Top up the tank and make a day trip of it.
Which airport is best for Mesopotamia?
Ioannina National Airport (IOA), located around 60 mi south of downtown Mesopotamia, is likely to be where you'll jet into. Your other options are Kastoria (KSO-Aristoteles) (7 mi away from central Mesopotamia) and Kozani (KZI-Filippos) (40 mi away from central Mesopotamia).
Where should I stay when visiting Mesopotamia?
The To Spiti tis Sofias is recommended by many visitors. Book soon to avoid missing out.

Photos of local treasures

Browse Mesopotamia vacation photos for more inspiration