Explore beach hotels in Matlacha Isles, FL
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Beach Condos in Matlacha Isles
New! Loggerhead Cay 572! Spring savings
Sanibel
10/10 Exceptional! (4 reviews)
Beach Villas in Matlacha Isles
Enchanting tropical waterfront villa with boat slip, bikes, kayaks heated pool!
Cape Coral
10/10 Exceptional! (59 reviews)
Popular Beach Stays in Matlacha Isles
Recent Matlacha Isles Hotel Reviews By Fellow Wanderers
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Clean and quiet place"
A verified traveler stayed at Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Explore More Ways to Travel with Travelocity
Explore More Ways to Travel with Travelocity
- Explore more Beach Resorts & Hotels
- Hotels Near...
- Areas Of Matlacha Isles
- Popular Beach Hotel Destinations
- Other Popular Beach Accommodation
An Attraction
- Hotels near Key West Express
- Hotels near Sanibel Island Southern Beach
- Hotels near Lee Health Sports Complex
- Hotels near Edison Mall
- Hotels near Estero Boulevard Beach
- Hotels near North Captiva Island Beach
- Hotels near Boca Grande Beach
- Hotels near Captiva Beach
- Hotels near Bowman's Beach
- Hotels near Edison and Ford Winter Estates
- Hotels near Bell Tower Shops
- Hotels near Bunche Beach
- Hotels near Cape Coral Yacht Club Beach
- Hotels near Sun Splash Water Park
- Hotels near Sanibel Island Lighthouse
- Hotels near Lynn Hall Memorial Park
- Hotels near Florida Southwestern State College
- Hotels near Gasparilla Island State Park
- Hotels near Sanibel Harbour
- Hotels near Barbara B Mann Hall
- Fort Myers Beach Hotels
- Fort Myers Hotels
- Sanibel Hotels
- Cape Coral Hotels
- Sanibel Captiva Island Hotels
- Florida Gulf Coast Hotels
- Punta Gorda Hotels
- Captiva Hotels
- Port Charlotte Hotels
- Boca Grande Hotels
- Captiva Island Hotels
- Estero Hotels
- Gulf Coast Hotels
- Placida Hotels
- Saint James City Hotels
- South Florida Hotels
- Gasparilla Island Hotels
- Lehigh Acres Hotels
- North Fort Myers Hotels
- Bokeelia Hotels
- Matlacha Hotels
- Little Gasparilla Island Hotels
- Gulf of Mexico Hotels
- Pine Island Hotels
- Southeastern United States Hotels
- Wulfert Hotels
- Southwest Coast Florida Hotels
- Southwest Florida Hotels
- Alva Hotels
- Pine Island Center Hotels
- Estero Island Hotels
- Burnt Store Marina Hotels
- Buckingham Hotels
- Truckland Hotels
- Fort Myers Shores Hotels
- Flamingo Bay Hotels
- Pineland Hotels
- Matlacha Isles-Matlacha Shores Hotels
- The South Hotels
- Cayo Costa State Park Hotels
- Daytona Beach Hotels
- Myrtle Beach Hotels
- Virginia Beach Hotels
- Miami Beach Hotels
- Panama City Beach Hotels
- Clearwater Beach Hotels
- Cocoa Beach Hotels
- Laguna Beach Hotels
- Fort Myers Beach Hotels
- San Diego Beach Hotels
- Orange Beach Hotels
- Huntington Beach Hotels
- Pensacola Beach Hotels
- South Beach Hotels
- Cannon Beach Hotels
- Pismo Beach Hotels
- Rosarito Beach Hotels
More Ways To Wander Matlacha Isles
Flights to Cape Coral
The best fares to get you there
Cape Coral Hotels
Cape Coral Vacation Rentals
Great Deals on Alternative Accommodations
Cape Coral Car Rentals
Affordable cars to get you around town
Cape Coral Vacations
Save more by combining flights, hotels and cars
Things to do in Cape Coral
Discover events, experiences & tours