Book Hotels in Matlacha Isles-Matlacha Shores, FL
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Top Matlacha Isles-Matlacha Shores hotels

Matlacha on Shoreview
12220-12230 Shoreview Dr, Cape Coral, FL
$125 nightly
The price is $139 total per night from Oct 21 to Oct 22
$139 total
Oct 21 - Oct 22
Total with taxes and fees
This hotel features a picnic area, laundry facilities, and barbecue grills. A virtual front desk are provided for your convenience.
"Wonderful"
Reviewed on Sep 28, 2025

Pink Shell Beach Resort and Marina
275 Estero Blvd, Fort Myers Beach, FL
Fully refundableReserve now, pay when you stay
$254 nightly
The price is $284 total per night from Oct 27 to Oct 28
$284 total
Oct 27 - Oct 28
Total with taxes and fees
A marina, 3 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy the gym and free buffet breakfast each morning. Enjoy the hot ...
"Clean room with beautiful views"
Reviewed on Oct 15, 2025

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
1538 Cape Coral Pkwy E, Cape Coral, FL
Fully refundable
$113 nightly
The price is $126 total per night from Oct 26 to Oct 27
$126 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
ECRM 2025 Convention
"Ricardo was very helpful and accommodating. Thank you for a great experience!"
Reviewed on Oct 13, 2025

Sanibel Island Beach Resort
1231 Middle Gulf Dr, Sanibel, FL
Fully refundableReserve now, pay when you stay
$220 nightly
The price is $243 total per night from Oct 27 to Oct 28
$243 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink ...
"Fabulous beautiful resort with all of the amenities- pool bar, pool, hammocks, beach lounge chairs, dining, and comfortable accommodations! A gem Highly recommended- we will return."
Reviewed on Oct 20, 2025

Lani Kai Beachfront Resort
1400 Estero Blvd, Fort Myers Beach, FL
Fully refundableReserve now, pay when you stay
$191 nightly
The price is $214 total per night from Oct 27 to Oct 28
$214 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel features 2 beach bars, a bar/lounge, and a restaurant. Enjoy the outdoor pool and perks like free WiFi. There's a poolside bar on site, and a 24-hour ...
"It’s great place beach is nice food was great the staff at the restaurant on the 1st floor were awesome both lunch and dinner got to meet the manager at dinner and was very impressed with his style he was top notch"
Reviewed on Oct 18, 2025

Margaritaville Beach Resort Fort Myers
251 Crescent Street, Fort Myers Beach, FL
$197 nightly
The price is $220 total per night from Oct 21 to Oct 22
$220 total
Oct 21 - Oct 22
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Relax with a drink at one of the 4 bars/lounges and get perks ...
"Loved everything about our stay"
Reviewed on Oct 18, 2025

Hilton Garden Inn Ft Myers
12600 University Dr, Fort Myers, FL
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $127 total per night from Oct 26 to Oct 27
$127 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"Nice place"
Reviewed on Oct 18, 2025

Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr, Fort Myers, FL
Fully refundableReserve now, pay when you stay
$211 nightly
The price is $236 total per night from Nov 2 to Nov 3
$236 total
Nov 2 - Nov 3
Total with taxes and fees
A full-service spa, 4 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy the 5 outdoor tennis courts and indoor pool, and unwind ...
"The grounds were beautiful and it was wonderful to sit on the balcony and watch the water and boats coming and going. My only negative is that there is no option for coffee until 7:00. So being an early riser, that was disappointing."
Reviewed on Oct 18, 2025

Baymont by Wyndham Fort Myers Central
4850 S Cleveland Ave, Fort Myers, FL
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $72 total per night from Oct 21 to Oct 22
$72 total
Oct 21 - Oct 22
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...
"The breakfast was ok. The hard boiled eggs were a good addition to the meal, good coffee The parking was great no problem parking in front of you room"
Reviewed on Oct 17, 2025
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Recent Matlacha Isles-Matlacha Shores hotel reviews by fellow wanderers

Sanibel Island Beach Resort
5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"Fabulous beautiful resort with all of the amenities- pool bar, pool, hammocks, beach lounge chairs, dining, and comfortable accommodations!
A gem
Highly recommended- we will return."
A verified traveler stayed at Sanibel Island Beach Resort
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