Book Hotels in Matlacha Isles-Matlacha Shores, FL

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Top Matlacha Isles-Matlacha Shores hotels

Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
$206 nightly
The price is $230 total per night from Aug 31 to Sep 1
$230 total
Aug 31 - Sep 1
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink ...
"Everything was clean and convenient for us! Especially the walking access to the beach that was a plus definitely will return there in the future."

Reviewed on Aug 30, 2026

Opens in a new windowSanibel Island Beach Resort
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$204 nightly
The price is $228 total per night from Sep 1 to Sep 2
$228 total
Sep 1 - Sep 2
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
"The hotel is new, very clean and"

Reviewed on Aug 29, 2026

Opens in a new windowMargaritaville Beach Resort Fort Myers
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$153 nightly
The price is $170 total per night from Aug 31 to Sep 1
$170 total
Aug 31 - Sep 1
Total with taxes and fees
This smoke-free hotel features 3 restaurants, 3 beach bars, and 6 bars/lounges. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Enjoy ...
"I had a wonderful experience…except that both mattresses in our room were sagging; one more than the other. Mine being the one with the largest dip in it. It also made a lot of noise when I moved. Next time I will definitely request a firm mattress!!! Everything else, and I literally mean EVERYTHING, ..."

Reviewed on Aug 29, 2026

Opens in a new windowLani Kai Beachfront Resort
The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

3 out of 5
1051 5th St Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $160 total per night from Sep 16 to Sep 17
$160 total
Sep 16 - Sep 17
Total with taxes and fees
This hotel features 2 outdoor pools, a restaurant, and a bar/lounge. Relax with a drink at the poolside bar and enjoy perks like free self parking and free WiFi. ...
"Great location for Fort Meyers beach. Our room was dated/worn and not particularly clean (bedsheets stained etc). That being said, our room was old in the older part of the resort, so the newer side may be better? On site bar is worth a visit for food/drink"

Reviewed on Aug 27, 2026

Opens in a new windowThe Lighthouse Resort Inn & Suites
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $74 total per night from Sep 6 to Sep 7
$74 total
Sep 6 - Sep 7
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...
"N/A"

Reviewed on Aug 28, 2026

Opens in a new windowBaymont by Wyndham Fort Myers Central
Matlacha on Shoreview

Matlacha on Shoreview

2 out of 5
12220-12230 Shoreview Dr Cape Coral FL
$125 nightly
The price is $139 total per night from Sep 1 to Sep 2
$139 total
Sep 1 - Sep 2
Total with taxes and fees
This hotel features a picnic area, laundry facilities, and barbecue grills. A virtual front desk are provided for your convenience.
Opens in a new windowMatlacha on Shoreview
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
$223 nightly
The price is $248 total per night from Sep 13 to Sep 14
$248 total
Sep 13 - Sep 14
Total with taxes and fees
A full-service spa, 4 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy the 5 outdoor tennis courts and indoor pool, and unwind ...
Opens in a new windowMarriott Sanibel Harbour Resort & Spa
Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

4 out of 5
275 Estero Blvd Fort Myers Beach FL
$263 nightly
The price is $293 total per night from Sep 29 to Sep 30
$293 total
Sep 29 - Sep 30
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 3 restaurants. Enjoy the 3 outdoor pools and free buffet breakfast each morning. Enjoy the ...
Opens in a new windowPink Shell Beach Resort and Marina
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 out of 5
1538 Cape Coral Pkwy E Cape Coral FL
Fully refundable
$101 nightly
The price is $113 total per night from Sep 30 to Oct 1
$113 total
Sep 30 - Oct 1
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Opens in a new windowHoliday Inn Express Cape Coral-Fort Myers Area by IHG
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Matlacha Isles-Matlacha Shores?
From well-thought-out amenities to rooms with bunk beds, kid-friendly hotels come with features that can help transform a regular family vacation into an amazing one. These Matlacha Isles-Matlacha Shores properties make traveling with your youngsters a piece of cake: Unpack your bags at Island Paradise 4 - Full furnishings w/ pool & beach!. It comes with a swimming pool, a playground and a talent for making families feel at home. 8 Person 2-Bedroom Condo with Waterview Balcony - Tarpon - Welcome to our stunning two-bedroom condo room with a balcony! is another top pick. After an exciting day of sightseeing, return to your comfy room and amenities like a swimming pool and pet-friendly facilities.
Where can I find cheap hotels in Matlacha Isles-Matlacha Shores?
At Travelocity you'll find really nice hotels in Matlacha Isles-Matlacha Shores at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Matlacha Isles-Matlacha Shores rather than in Matlacha Isles-Matlacha Shores. We may find you even better rates, too.
How do I find the best Matlacha Isles-Matlacha Shores hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Matlacha Isles-Matlacha Shores then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Matlacha Isles-Matlacha Shores?
The cheapest hotel in Matlacha Isles-Matlacha Shores is $74. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Matlacha Isles-Matlacha Shores?
There are 15,079 hotels in Matlacha Isles-Matlacha Shores on Travelocity.
What are the best hotels in Matlacha Isles-Matlacha Shores?
Matlacha Isles-Matlacha Shores has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Matlacha Isles-Matlacha Shores for you!
When is the best time to visit Matlacha Isles-Matlacha Shores?
If you want the joy of a fun-filled trip in peak season, visit Matlacha Isles-Matlacha Shores during December, January and February. If you'd prefer the peace of off-season, book a stay during quieter months, such as May, September and October.
When is the cheapest time to stay in Matlacha Isles-Matlacha Shores?
Based on historic data is usually the cheapest month to visit Matlacha Isles-Matlacha Shores. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Matlacha Isles-Matlacha Shores?
There are multiple hotels in Matlacha Isles-Matlacha Shores that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Matlacha Isles-Matlacha Shores. We have plenty of kid-friendly hotels in Matlacha Isles-Matlacha Shores to choose from on Travelocity!
Why book a hotel in Matlacha Isles-Matlacha Shores through Travelocity?
Because we have the top hotels in Matlacha Isles-Matlacha Shores! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Matlacha Isles-Matlacha Shores on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Matlacha Isles-Matlacha Shores hotel reviews by fellow wanderers

Sanibel Island Beach Resort

Sanibel Island Beach Resort

5 out of 5
Posted 9 hours ago
Travelocity Verified Review
"Everything was clean and convenient for us! Especially the walking access to the beach that was a plus definitely will return there in the future."
A verified traveler stayed at Sanibel Island Beach Resort
Sanibel Island Beach Resort

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