Find a Hotel in Lake Nona Medical City

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Top hotels in Lake Nona Medical City

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

4 out of 5
8800 Vistana Centre Dr, Orlando, FL
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $103 total per night from Nov 17 to Nov 18
$103 total
Nov 17 - Nov 18
Total with taxes and fees
This smoke-free hotel features 3 restaurants, 6 outdoor pools, and 10 outdoor tennis courts. There's fun for all ages with a free kid's club and mini golf, and ...
"The room was great and clean"

Reviewed on Oct 12, 2025

Opens in a new windowSheraton Vistana Resort Villas, Lake Buena Vista/Orlando
Sheraton Vistana Villages Resort Villas, I-Drive/Orlando

Sheraton Vistana Villages Resort Villas, I-Drive/Orlando

4 out of 5
12401 International Dr, Orlando, FL
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $95 total per night from Nov 10 to Nov 11
$95 total
Nov 10 - Nov 11
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 5 outdoor pools, and 2 outdoor tennis courts. Bring the family and enjoy the children's club, children's pool, ...
Great place for family
"Spacious clean rooms. Good atmosphere. Staff nice but could communicate better to relay changes clearly to one another or changing shifts."

Reviewed on Oct 12, 2025

Opens in a new windowSheraton Vistana Villages Resort Villas, I-Drive/Orlando
Hyatt Regency Orlando

Hyatt Regency Orlando

4.5 out of 5
9801 International Dr, Orlando, FL
Fully refundableReserve now, pay when you stay
$184 nightly
The price is $207 total per night from Nov 15 to Nov 16
$207 total
Nov 15 - Nov 16
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this luxury hotel. Bring the family and enjoy the children's pool, free theme park ...
"great hotel and friendly staff. nice location. room is clean"

Reviewed on Oct 15, 2025

Opens in a new windowHyatt Regency Orlando
Universal's Cabana Bay Beach Resort

Universal's Cabana Bay Beach Resort

3.5 out of 5
6550 Adventure Way, Orlando, FL
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $150 total per night from Nov 5 to Nov 6
$150 total
Nov 5 - Nov 6
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 2 outdoor pools, and 2 hot tubs. There's fun for all ages with a lazy river and a bowling alley, and families will ...
"A door to block noise from end of rooms to the food court. It was so loud late into the night and early mornings. Our room was a terrible location. We were in 4102 The shower by the jacuzzi never turned off. Talk about a waste of water!!!"

Reviewed on Oct 14, 2025

Opens in a new windowUniversal's Cabana Bay Beach Resort
Marriott's Grande Vista

Marriott's Grande Vista

4 out of 5
5925 Avenida Vista, Orlando, FL
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $107 total per night from Nov 10 to Nov 11
$107 total
Nov 10 - Nov 11
Total with taxes and fees
This eco-certified hotel features a golf course, a full-service spa, and 3 restaurants. There's fun for all ages with mini golf and a children's pool, and barbecue ...
"Our room was clean and spacious! The property is clean and near major Orlando attractions. Thank you for a great stay!"

Reviewed on Oct 13, 2025

Opens in a new windowMarriott's Grande Vista
DoubleTree by Hilton Orlando Airport

DoubleTree by Hilton Orlando Airport

4 out of 5
5555 Hazeltine National Drive, Orlando, FL
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Oct 26 to Oct 27
$105 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free WiFi and a free airport shuttle. You'll appreciate ...
"The hotel is very clean, and convenient to airport."

Reviewed on Oct 11, 2025

Opens in a new windowDoubleTree by Hilton Orlando Airport
Holiday Inn Resort Kissimmee by the Parks by IHG

Holiday Inn Resort Kissimmee by the Parks by IHG

3.5 out of 5
3011 Maingate Ln, Kissimmee, FL
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Oct 26 to Oct 27
$79 total
Oct 26 - Oct 27
Total with taxes and fees
2 outdoor pools, a 24-hour gym, and a hot tub are all featured at this smoke-free hotel. Bring the family and enjoy the children's pool, playground, and kid-friendly ...
"Noisy family next door with multiple small children."

Reviewed on Oct 11, 2025

Opens in a new windowHoliday Inn Resort Kissimmee by the Parks by IHG
DoubleTree by Hilton at the Entrance to Universal Orlando

DoubleTree by Hilton at the Entrance to Universal Orlando

4 out of 5
5780 Major Blvd, Orlando, FL
Fully refundable
$98 nightly
The price is $110 total per night from Oct 27 to Oct 28
$110 total
Oct 27 - Oct 28
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. There's fun for all ages with a children's pool and an arcade/game room, and ...
"Great hotel"

Reviewed on Oct 15, 2025

Opens in a new windowDoubleTree by Hilton at the Entrance to Universal Orlando
DoubleTree by Hilton Hotel Orlando at SeaWorld

DoubleTree by Hilton Hotel Orlando at SeaWorld

4 out of 5
10100 International Drive, Orlando, FL
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $115 total per night from Oct 26 to Oct 27
$115 total
Oct 26 - Oct 27
Total with taxes and fees
This smoke-free resort features 2 restaurants, 2 outdoor pools, and a 24-hour gym. There's fun for all ages with mini golf and a children's pool, and families ...
"Very well situated gym. Standing water between parked car and elevator all four days of our stay. No luggage stand in the room for our suitcases. No shower cap, qtips, tiny trash can in bathroom and not in main room. No pad or pen to use. The one tiny soap we were given for the sink was thrown away ..."

Reviewed on Oct 15, 2025

Opens in a new windowDoubleTree by Hilton Hotel Orlando at SeaWorld
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Lake Nona Medical City Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Lake Nona Medical City area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Lake Nona Medical City to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Lake Nona Medical City are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Lake Nona Medical City hotel reviews by fellow wanderers

DoubleTree by Hilton at the Entrance to Universal Orlando

DoubleTree by Hilton at the Entrance to Universal Orlando

5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Great hotel "
A verified traveler stayed at DoubleTree by Hilton at the Entrance to Universal Orlando
DoubleTree by Hilton at the Entrance to Universal Orlando

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