Find a Hotel in Lake Nona Medical City
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Top hotels in Lake Nona Medical City
Hyatt Regency Orlando International Airport
9300 Jeff Fuqua Boulevard, Orlando, FL
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $201 total per night from Oct 13 to Oct 14
$201 total
Oct 13 - Oct 14
Total with taxes and fees
This eco-certified hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free ...
"Staff very helpful and friendly. They help get you to your cruise pick up and do it with a smile. Had a great stay. Very convenient and clean. Comfortable bed."
Reviewed on Oct 5, 2025
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
8800 Vistana Centre Dr, Orlando, FL
$99 nightly
The price is $112 total per night from Oct 28 to Oct 29
$112 total
Oct 28 - Oct 29
Total with taxes and fees
This smoke-free hotel features 3 restaurants, 6 outdoor pools, and 10 outdoor tennis courts. There's fun for all ages with a free kid's club and mini golf, and ...
"Perfect"
Reviewed on Oct 6, 2025
Sheraton Vistana Villages Resort Villas, I-Drive/Orlando
12401 International Dr, Orlando, FL
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $98 total per night from Oct 28 to Oct 29
$98 total
Oct 28 - Oct 29
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 5 outdoor pools, and 2 outdoor tennis courts. Bring the family and enjoy the children's club, children's pool, ...
"I loved the Bella’s villas very spacious two bed rooms Also very big property with a lot to do ."
Reviewed on Oct 5, 2025
Universal's Cabana Bay Beach Resort
6550 Adventure Way, Orlando, FL
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $158 total per night from Nov 5 to Nov 6
$158 total
Nov 5 - Nov 6
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 2 outdoor pools, and 2 hot tubs. There's fun for all ages with a lazy river and a bowling alley, and families will ...
"Amazing"
Reviewed on Oct 2, 2025
Marriott's Grande Vista
5925 Avenida Vista, Orlando, FL
$87 nightly
The price is $98 total per night from Oct 28 to Oct 29
$98 total
Oct 28 - Oct 29
Total with taxes and fees
This eco-certified hotel features a golf course, a full-service spa, and 3 restaurants. There's fun for all ages with mini golf and a children's pool, and barbecue ...
"Rooms were very nice and spacious"
Reviewed on Oct 3, 2025
DoubleTree by Hilton Orlando Airport
5555 Hazeltine National Drive, Orlando, FL
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $109 total per night from Oct 27 to Oct 28
$109 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free WiFi and a free airport shuttle. You'll appreciate ...
"Super"
Reviewed on Oct 6, 2025
DoubleTree by Hilton at the Entrance to Universal Orlando
5780 Major Blvd, Orlando, FL
$89 nightly
The price is $100 total per night from Nov 2 to Nov 3
$100 total
Nov 2 - Nov 3
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. There's fun for all ages with a children's pool and an arcade/game room, and ...
"Comfortable and convenient"
Reviewed on Oct 1, 2025
Westgate Lakes Resort & Spa Universal Studios Area
9500 Turkey Lake Rd, Orlando, FL
$117 nightly
The price is $132 total per night from Oct 14 to Oct 15
$132 total
Oct 14 - Oct 15
Total with taxes and fees
This smoke-free hotel features a full-service spa, a water park, and a marina. There's fun for all ages with a lazy river and a children's club, and barbecue ...
"Good"
Reviewed on Oct 1, 2025
DoubleTree by Hilton Hotel Orlando at SeaWorld
10100 International Drive, Orlando, FL
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $113 total per night from Nov 6 to Nov 7
$113 total
Nov 6 - Nov 7
Total with taxes and fees
This smoke-free resort features 2 restaurants, 2 outdoor pools, and a 24-hour gym. There's fun for all ages with mini golf and a children's pool, and families ...
"The staff was awesome"
Reviewed on Oct 2, 2025
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lake Nona Medical City Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Lake Nona Medical City area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Lake Nona Medical City to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Lake Nona Medical City are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Lake Nona Medical City hotel reviews by fellow wanderers
Wyndham I-Drive Avanti Resort & Conference Center
5 out of 5
Posted 19 hours ago
Travelocity Verified Review
"Everything for our stay was perfect! Check in and out was pretty easy. Staff was amazing and friendly!! Thank you for a wonderful stay!!"
A verified traveler stayed at Wyndham I-Drive Avanti Resort & Conference Center
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