Explore 9 Luxury Hotels in Lake City

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Best Luxury Hotels in Lake City

Comfort Suites Lake City

Comfort Suites Lake City

3690 W Us Highway 90 Lake City FL
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $122 total per night from Apr 22 to Apr 23
$122 total
Apr 22 - Apr 23
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
9.6/10 Exceptional! (1,003 reviews)
The staff was very nice, breakfast was good and they kept a watch on to replace any items that needed. The room was clean, the beds comfortable. We had a wonderful stay.

Reviewed on Apr 13, 2026

Opens in a new windowComfort Suites Lake City
Americas Best Value Inn Lake City

Americas Best Value Inn Lake City

3835 West US Highway 90 Lake City FL
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $76 total per night from Apr 22 to Apr 23
$76 total
Apr 22 - Apr 23
Total with taxes and fees
An outdoor pool is featured at this motel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. ...
8.8/10 Excellent! (1,012 reviews)
A/C worked great

Reviewed on Apr 20, 2026

Opens in a new windowAmericas Best Value Inn Lake City
Driftwood Inn

Driftwood Inn

2764 W US Hwy 90 Lake City FL
Fully refundableReserve now, pay when you stay
$53 nightly
The price is $60 total per night from Apr 23 to Apr 24
$60 total
Apr 23 - Apr 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
7.8/10 Good! (778 reviews)
10:51 • a 100 Driftwood Inn Tim T. 4 minutes ago ... This place is an absolute dump. There were three homeless looking people down at the end. No lighting whatsoever in the parking lot. The "managers" barely spoke English and didn't care about my concerns at all. Don't stay, I going to leave my truck ...

Reviewed on Mar 15, 2026

Opens in a new windowDriftwood Inn
Palms Garden Inn

Palms Garden Inn

14113 S. US Hwy 441 Lake City FL
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $73 total per night from Apr 22 to Apr 23
$73 total
Apr 22 - Apr 23
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Express check-out and laundry facilities are also provided.
7.4/10 Good! (603 reviews)
If you just need a place to rest on a road trip, this is perfect. The property is dated, but clean and well-kept, and has a certain sense of nostalgia. The beds are very comfortable and the sheets were very soft. Staff is very friendly.

Reviewed on Mar 28, 2026

Opens in a new windowPalms Garden Inn
Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City

3954 SW State Road 47 Lake City FL
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $71 total per night from May 10 to May 11
$71 total
May 10 - May 11
Total with taxes and fees
A restaurant and an outdoor pool are featured at this motel. There's no skimping on freebies - guests receive free cooked-to-order breakfast, free WiFi, and ...
7.4/10 Good! (707 reviews)
Cooked eggs and sausage to order

Reviewed on Apr 18, 2026

Opens in a new windowSuper 8 by Wyndham Lake City
Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10

3430 N Us Highway 441 Lake City FL
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $68 total per night from Apr 22 to Apr 23
$68 total
Apr 22 - Apr 23
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
7/10 Good! (1,002 reviews)
It was awesome.

Reviewed on Apr 18, 2026

Opens in a new windowDays Inn by Wyndham Lake City I-10
Econo Lodge Lake City-North

Econo Lodge Lake City-North

178 Sw Florida Gateway Dr Lake City FL
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $77 total per night from Apr 27 to Apr 28
$77 total
Apr 27 - Apr 28
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...
6.8/10 (404 reviews)
Room was so dirty. Pull out couch had some kind of stain down the front, looked like maybe vomit? The baseboards were peeling from the walls with the walls disintegrating behind them. Of all the nicer places we stayed on our way to Florida, this was the most expensive and the worst condition. Do ...

Reviewed on Apr 5, 2026

Opens in a new windowEcono Lodge Lake City-North
Rodeway Inn Lake City I-75

Rodeway Inn Lake City I-75

205 Sw Commerce Dr Lake City FL
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Apr 27 to Apr 28
$76 total
Apr 27 - Apr 28
Total with taxes and fees
A restaurant, free self parking, and a 24-hour front desk are among this hotel's amenities. Guests will appreciate free perks like continental breakfast and ...
6.8/10 (394 reviews)
It was listed as having a breakfast included, upon arrival was informed that they no longer have the breakfast.

Reviewed on Mar 30, 2026

Opens in a new windowRodeway Inn Lake City I-75
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Lake City Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Lake City luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Lake City to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Lake City will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Lake City, and plan your next opulent escape.


Lake City hotels essential information

Accommodation
420 hotels
Lowest Price
$60
Highest Price
$122
Popular hotels
Palms Garden Inn, Americas Best Value Inn Lake City, Driftwood Inn, Econo Lodge Lake City-North, Comfort Suites Lake City, Days Inn by Wyndham Lake City I-10, Super 8 by Wyndham Lake City, Rodeway Inn Lake City I-75

Popular Luxury Stays in Lake City

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