Greenville Vacation Packages 2025/2026 from $379

Greenville flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Motel 6 Greenville, NC – ECU-Medical Center

$379

per person

Nov 5 - Nov 9

found 1 day ago

Roundtrip non-stop flight included

Tampa (TPA) to Greenville (PGV)

A seasonal outdoor pool, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A snack bar/deli, a picnic area, and luggage storage are also on offer.

Top Greenville hotels deals

Staybridge Suites Greenville Medical Center by IHG

930 Crosswind Street, Greenville, NC

Free Cancellation

$107 total

per night

Oct 26 - Oct 27

This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free buffet breakfast each morning. A grocery/convenience store, a lobby fireplace, and a computer station are also on offer.

Breakfast included

Parking included

Microtel Inn & Suites by Wyndham Greenville/University Medic

450 Moye Blvd, Greenville, NC

Free Cancellation

Reserve now, pay when you stay

$82 total

per night

Oct 7 - Oct 8

A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A coffee shop and a safe deposit box are also provided.

Breakfast included

Parking included

Comfort Inn & Suites Greenville Near Convention Center

3212 S Memorial Dr, Greenville, NC

Free Cancellation

Reserve now, pay when you stay

$121 total

per night

Oct 12 - Oct 13

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Pool

Breakfast included

Best Western Plus Suites-Greenville

2310 Greenville Boulevard NE, Greenville, NC

Free Cancellation

Reserve now, pay when you stay

$123 total

per night

Oct 26 - Oct 27

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like full breakfast and free self parking.

Pool

Breakfast included

Quality Inn Greenville near University

821 Memorial Dr, Greenville, NC

Free Cancellation

Reserve now, pay when you stay

$91 total

per night

Oct 7 - Oct 8

This hotel features a gym and a seasonal outdoor pool. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

Pool

Breakfast included

Holiday Inn Greenville by IHG

203 Greenville Blvd SW, Greenville, NC

Free Cancellation

$125 total

per night

Oct 7 - Oct 8

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and perks like free self parking.

Pool

Parking included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

East Carolina University

Enjoy the collegiate vibe when you visit East Carolina University, during your trip to Greenville. Check out the shops and top-notch restaurants in this family-friendly area.

ECU Health Medical Center

Though ECU Health Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Greenville while you are here.

Greenville VA Medical Center

Though Greenville VA Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Greenville while you are here.

Frequently asked questions

How much are vacation packages to Greenville?

You can find a fantastic hotel + flight bundle for an affordable $379. With one of our Travelocity vacation packages, a getaway in Greenville has never looked more enticing! Save your time and cash and then get a start on packing those bags.

How long should my Greenville vacation be?

Most visitors stay in Greenville for around 2 nights. But traveling is all about discovering hidden gems and creating cherished memories — why not book a few extra nights to do just that?

Where can I get the best vacation package deals for Greenville?

You can score fantastic Greenville package deals with Travelocity. Select from as many as 400 airlines and 1,000,000 properties worldwide and turn those vacation dreams into reality.

Why should I book my Greenville vacation bundle with Travelocity?

Because life is all about the journey, and we've got everything you could hope for to help you along the way. With our exceptional service and Price Match Guarantee, you can book your trip with confidence. And you can sleep easy while you're on the road knowing you can reach us with our 24/7 customer support.

Can I save on my Greenville car rental if I book it with a hotel or flight?

Bundling your flight, hotel and car into a Greenville vacation package is a surefire way to score an amazing deal. Plus, having your own rental car gives you absolute freedom to find your way to all the landmarks you're itching to check out. Sitting 120 mi away from Greenville, Busch Gardens Williamsburg is one attraction that should be on your can't-miss list. Turn up the tunes and make a day trip of it.

Which airport is best for Greenville?

There are two choices for flying into Greenville, the first one being Craven Regional Airport (EWN). It's about 40 mi from the city center, while Pitt-Greenville Airport (PGV) is 2 mi away from central Greenville.

What is there to do in Greenville?

While hopping off the tourist trail is no doubt rewarding, you shouldn't miss the big-name sights that make a place famous. East Carolina University and Dowdy–Ficklen Stadium are a couple of them in Greenville.

Where should I stay when visiting Greenville?

If you're after somewhere to lay your head, check out the Best Western Plus Suites-Greenville. It's the top pick for many travelers.

Where to stay in Greenville: Best areas for travelers

Washington: To explore the wonderful great outdoors, stop by this neighborhood and get a dose of nature at Goose Creek State Park. Consider basing yourself at the Days Inn by Wyndham Washington or the Magnuson Hotel Washington. Alternatively, unpack your bags at the Econo Lodge North.
Kinston: Whatever brings you to this neighborhood, it won't be long until you get won over by its charms. CSS Neuse II, Mother Earth Brewing, Grainger Stadium — there's plenty to keep you on your feet. Some favorite hotels here include the Mother Earth Motor Lodge, the Quality Inn Kinston Hwy 70 and the Nation's Inn Kinston.
Williamston: The chance to disconnect is one of the reasons this neighborhood is so popular. Take a stroll around Kekukee Park and bask in the peaceful ambiance. When you're not spending time in nature, you can look forward to some downtime at the Quality Inn, the Magnuson Hotel Williamston or the Hotel Williamston NC Route 17 & Hwy 64.