Find & Compare 2 Adults-Only Hotels & Resorts in San Diego With Rates at
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Adults Only Resorts in Downtown San Diego
Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
This eco-certified hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi ...
9/10 Wonderful! (2,789 reviews)
"The hotel staff was very friendly and helpful with anything I needed."
Reviewed on Jun 20, 2025
Don't see what you're looking for?
See all available properties in Downtown San Diego
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find 5-Star Hotels in Downtown San Diego
Pendry San Diego
550 J Street, San Diego, CA
9.2/10 Wonderful! (1,004 reviews)
Search All-Inclusive Hotels in Downtown San Diego
Hilton San Diego Bayfront
1 Park Blvd, San Diego, CA
8.4/10 Very Good! (1,555 reviews)
Popular Adults Only Stays in Downtown San Diego
Recent Downtown San Diego hotel reviews by fellow wanderers
Manchester Grand Hyatt San Diego
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"The hotel staff was very friendly and helpful with anything I needed. "
A verified traveler stayed at Manchester Grand Hyatt San Diego
Explore More Ways to Travel with Travelocity
Explore More Ways to Travel with Travelocity
- Explore More
- Other Hotel Types
- Explore Neighborhoods in Downtown San Diego
- Adult Only Hotels & Resorts in other Cities
An attraction
- Hotels near San Diego Convention Center
- Hotels near Petco Park
- Hotels near Port of San Diego
- Hotels near USS Midway Museum
- Hotels near Seaport Village
- Hotels near B Street Cruise Ship Terminal
- Hotels near Waterfront Park
- Hotels near Maritime Museum of San Diego
- Hotels near San Diego Civic Theatre
- Hotels near San Diego City College
- Hotels near Navy Pier
- Hotels near New Children's Museum
- Hotels near Star of India
- Hotels near Our Lady of the Rosary Catholic Church
- Hotels near Museum of Contemporary Art San Diego
- Hotels near A National Salute to Bob Hope & the Military
- Hotels near Gaslamp Museum at the Davis-Horton House
- Hotels near Lyceum Theatre
- Hotels near Copley Symphony Hall
- Hotels near American Plaza
- Hotels near Balboa Stadium
- Hotels near San Diego Opera
- Hotels near San Diego Repertory Theater
- Hotels near Firehouse Museum
- Hotels near San Diego Chinese Historical Museum
- Hotels near Spreckels Theater
- Hotels near Pantoja Park
- Hotels near Balboa Park
- Hotels near San Diego Bay
Types of Hotels
- Adults Only Resorts & Hotels in Pacific Beach
- Adults Only Resorts & Hotels in Mission Beach
- Adults Only Resorts & Hotels in Gaslamp Quarter
- Adults Only Resorts & Hotels in Ocean Beach
- Adults Only Resorts & Hotels in Point Loma
- Adults Only Resorts & Hotels in Mission Valley
- Adults Only Resorts & Hotels in Central Mission Beach
- Adults Only Resorts & Hotels in Old Town San Diego
- Adults Only Resorts & Hotels in Little Italy
- Adults Only Resorts & Hotels in Mid-City
- Adults Only Resorts & Hotels in Carmel Valley
- Adults Only Resorts & Hotels in Hillcrest
- Hotels with Air Conditioning in Downtown San Diego
- Kid Friendly Hotels in Downtown San Diego
- Hotels with Restaurants in Downtown San Diego
- Beach Resorts & Hotels in Downtown San Diego
- Hotels with a Gym in Downtown San Diego
- Hotels with Shopping in Downtown San Diego
- Convention Center Hotels in Downtown San Diego
- Hotels with Pools in Downtown San Diego
- Historic Hotels in Downtown San Diego
- Golf Resorts & Hotels in Downtown San Diego
- Hotels with Bar in Downtown San Diego
- Adventure Hotels in Downtown San Diego
- Cheap Hotels in Downtown San Diego
- Luxury Hotels in Downtown San Diego
- Romantic Getaways & Hotels in Downtown San Diego
- Hotels with Room Service in Downtown San Diego
- Hotels with Free Breakfast in Downtown San Diego
- Hotels with Free Parking in Downtown San Diego
- Hotels with Balconies in Downtown San Diego
- Pet Friendly Hotels in Downtown San Diego
- Hotel Wedding Venues in Downtown San Diego
- Spa Resorts & Hotels in Downtown San Diego
- Hotels with Hot Tubs in Downtown San Diego
- Boutique Hotels in Downtown San Diego
- Hotels with Early Check-in in Downtown San Diego
- Hotels with Suites in Downtown San Diego
- Oceanfront Hotels in Downtown San Diego
- Hotels with Airport Transfers in Downtown San Diego
- Hotels with Free Airport Shuttle in Downtown San Diego
- Hotels with smoking rooms in Downtown San Diego
- Hotels with Kitchenettes in Downtown San Diego
- Green Hotels in Downtown San Diego
- Hotels on the River in Downtown San Diego
- Hotels on the Lake in Downtown San Diego
- Hotels with Childcare in Downtown San Diego
- Hotels with Tennis Courts in Downtown San Diego
- Hotels with an Indoor Pool in Downtown San Diego
- Arcade Hotels in Downtown San Diego
- Fishing Resorts & Hotels in Downtown San Diego
- Hotels with Waterslides in Downtown San Diego
- Gay Friendly Hotels in Downtown San Diego
- All Inclusive Resorts & Hotels in Downtown San Diego
Areas of Downtown San Diego
- San Diego Hotels
- La Jolla Hotels
- Chula Vista Hotels
- Coronado Hotels
- Del Mar Hotels
- Coronado Island Hotels
- El Cajon Hotels
- Solana Beach Hotels
- Southern California Hotels
- National City Hotels
- Poway Hotels
- La Mesa Hotels
- Imperial Beach Hotels
- Rancho Santa Fe Hotels
- San Ysidro Hotels
- Santee Hotels
- Spring Valley Hotels
- Lakeside Hotels
- Bonita Hotels
- San Diego Coast Hotels
- Jamul Hotels
- Lemon Grove Hotels
- Casa de Oro-Mount Helix Hotels
- Pacific Coast Highway Hotels
- Fairbanks Ranch Hotels
- Beach Cities San Diego County Hotels
- Western United States Hotels
- Rancho San Diego Hotels
- Crest Hotels
- South Bay Hotels
- Central America Hotels
- La Presa Hotels
- North Mission Beach Hotels
- South San Diego Hotels
- Winter Gardens Hotels
- Mexican Riviera Hotels
- Bostonia Hotels
- Granite Hills Hotels
- North Central San Diego Hotels
- Fiesta Island Hotels
Adult Only Hotels & Resorts in other Cities
- Adult Only Hotels in Orlando
- Adult Only Hotels in Myrtle Beach
- Adult Only Hotels in South Padre
- Adult Only Hotels in Seven Mile
- Adult Only Hotels in Destin
- Adult Only Hotels in Wisconsin Dells
- Adult Only Hotels in Florida Keys
- Adult Only Hotels in Dallas
- Adult Only Hotels in Cancun
- Adult Only Hotels in St John
- Adult Only Hotels in Houston
- Adult Only Hotels in Miami Beach
- Adult Only Hotels in New York
- Adult Only Hotels in Cozumel
- Adult Only Hotels in Bora Bora
- Adult Only Hotels in Pensacola
- Adult Only Hotels in Michigan
- Adult Only Hotels in Georgia
- Adult Only Hotels in Lake Ozark
- Adult Only Hotels in Atlantic City
Most popular
Hotels
Hotels in Sorrento ValleyHotels in Carmel ValleyHotels in Liberty StationPoint Loma Cheap HotelsHotels in Mission BeachGaslamp Quarter Hotels with Hot TubsHotels in Point LomaHotels in Ocean BeachHotels in Gaslamp QuarterGaslamp Quarter Pet Friendly HotelsHotels in Old Town San DiegoHotels in Mira MesaOld Town San Diego Pet Friendly HotelsHotels in Rancho BernardoHotels in MiramarGaslamp Quarter Cheap HotelsHotels in Pacific BeachPacific Beach Beach Resorts & HotelsHotels in Mission ValleyHotels in Bankers HillLittle Italy Cheap HotelsOcean Beach Pet Friendly Hotels
Cars
Packages