Find & Compare 2 Adults-Only Hotels & Resorts in San Diego With Rates at from $252
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Adults Only Resorts in Downtown San Diego
Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
$217 nightly
The price is $252 total per night from Aug 31 to Sep 1
$252 total
Aug 31 - Sep 1
Total includes taxes and fees
This eco-certified hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi ...
8.8/10 Excellent! (2,789 reviews)
"Convenient"
Reviewed on Aug 6, 2025
Don't see what you're looking for?
See all available properties in Downtown San Diego
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find 5-Star Hotels in Downtown San Diego
Pendry San Diego
550 J Street, San Diego, CA
$301 nightly
The price is $349 total per night from Aug 21 to Aug 22
$349 total
Aug 21 - Aug 22
Total includes taxes and fees
9.2/10 Wonderful! (1,000 reviews)
Search All-Inclusive Hotels in Downtown San Diego
Hilton San Diego Bayfront
1 Park Blvd, San Diego, CA
$235 nightly
The price is $272 total per night from Aug 14 to Aug 15
$272 total
Aug 14 - Aug 15
Total includes taxes and fees
8.4/10 Very Good! (1,636 reviews)
Popular Adults Only Stays in Downtown San Diego
Recent Downtown San Diego hotel reviews by fellow wanderers
Manchester Grand Hyatt San Diego
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Convenient "
A verified traveler stayed at Manchester Grand Hyatt San Diego
Explore More Ways to Travel with Travelocity
Explore More Ways to Travel with Travelocity
- Explore More
- Other Hotel Types
- Explore Neighborhoods in Downtown San Diego
- Adult Only Hotels & Resorts in other Cities
An attraction
- Hotels near San Diego Convention Center
- Hotels near Petco Park
- Hotels near Port of San Diego
- Hotels near USS Midway Museum
- Hotels near Seaport Village
- Hotels near B Street Cruise Ship Terminal
- Hotels near Waterfront Park
- Hotels near Maritime Museum of San Diego
- Hotels near The Rady Shell at Jacobs Park
- Hotels near San Diego City College
- Hotels near Navy Pier
- Hotels near San Diego Civic Theatre
- Hotels near New Children's Museum
- Hotels near Copley Symphony Hall
- Hotels near Our Lady of the Rosary Catholic Church
- Hotels near Museum of Contemporary Art San Diego
- Hotels near A National Salute to Bob Hope & the Military
- Hotels near Star of India
- Hotels near Balboa Stadium
- Hotels near Spreckels Theater
- Hotels near American Plaza
- Hotels near San Diego Chinese Historical Museum
- Hotels near Firehouse Museum
- Hotels near Pantoja Park
- Hotels near Balboa Park
- Hotels near San Diego Bay
Hotels by star rating
Types of Hotels
- Adults Only Resorts & Hotels in Mission Beach
- Adults Only Resorts & Hotels in Pacific Beach
- Adults Only Resorts & Hotels in Gaslamp Quarter
- Adults Only Resorts & Hotels in Ocean Beach
- Adults Only Resorts & Hotels in Point Loma
- Adults Only Resorts & Hotels in Mission Valley
- Adults Only Resorts & Hotels in Central Mission Beach
- Adults Only Resorts & Hotels in Old Town San Diego
- Adults Only Resorts & Hotels in Little Italy
- Adults Only Resorts & Hotels in Carmel Valley
- Adults Only Resorts & Hotels in Hillcrest
- Adults Only Resorts & Hotels in Mid-City
- Hotels with Air Conditioning in Downtown San Diego
- Kid Friendly Hotels in Downtown San Diego
- Hotels with Restaurants in Downtown San Diego
- Beach Resorts & Hotels in Downtown San Diego
- Hotels with a Gym in Downtown San Diego
- Hotels with Shopping in Downtown San Diego
- Convention Center Hotels in Downtown San Diego
- Hotels with Pools in Downtown San Diego
- Historic Hotels in Downtown San Diego
- Golf Resorts & Hotels in Downtown San Diego
- Hotels with Bar in Downtown San Diego
- Adventure Hotels in Downtown San Diego
- Cheap Hotels in Downtown San Diego
- Luxury Hotels in Downtown San Diego
- Romantic Getaways & Hotels in Downtown San Diego
- Hotels with Room Service in Downtown San Diego
- Hotels with Free Breakfast in Downtown San Diego
- Hotels with Free Parking in Downtown San Diego
- Hotels with Balconies in Downtown San Diego
- Pet Friendly Hotels in Downtown San Diego
- Hotel Wedding Venues in Downtown San Diego
- Spa Resorts & Hotels in Downtown San Diego
- Hotels with Hot Tubs in Downtown San Diego
- Boutique Hotels in Downtown San Diego
- Hotels with Early Check-in in Downtown San Diego
- Hotels with Suites in Downtown San Diego
- Oceanfront Hotels in Downtown San Diego
- Hotels with Airport Transfers in Downtown San Diego
- Hotels with Free Airport Shuttle in Downtown San Diego
- Hotels with smoking rooms in Downtown San Diego
- Hotels with Kitchenettes in Downtown San Diego
- Green Hotels in Downtown San Diego
- Hotels on the River in Downtown San Diego
- Hotels on the Lake in Downtown San Diego
- Hotels with Childcare in Downtown San Diego
- Hotels with Tennis Courts in Downtown San Diego
- Hotels with an Indoor Pool in Downtown San Diego
- Arcade Hotels in Downtown San Diego
- Fishing Resorts & Hotels in Downtown San Diego
- Hotels with Waterslides in Downtown San Diego
- Gay Friendly Hotels in Downtown San Diego
- All Inclusive Resorts & Hotels in Downtown San Diego
Areas of Downtown San Diego
- San Diego Hotels
- La Jolla Hotels
- Chula Vista Hotels
- Coronado Hotels
- Del Mar Hotels
- Coronado Island Hotels
- El Cajon Hotels
- Solana Beach Hotels
- National City Hotels
- Southern California Hotels
- La Mesa Hotels
- Imperial Beach Hotels
- San Ysidro Hotels
- Poway Hotels
- Rancho Santa Fe Hotels
- Santee Hotels
- Spring Valley Hotels
- Casa de Oro-Mount Helix Hotels
- Lakeside Hotels
- Bonita Hotels
- San Diego Coast Hotels
- Lemon Grove Hotels
- Jamul Hotels
- Pacific Coast Highway Hotels
- Western United States Hotels
- Fairbanks Ranch Hotels
- Beach Cities San Diego County Hotels
- Rancho San Diego Hotels
- Central America Hotels
- La Presa Hotels
- South Bay Hotels
- South San Diego Hotels
- Winter Gardens Hotels
- Mexican Riviera Hotels
- North Mission Beach Hotels
- Central San Diego Hotels
- North Central San Diego Hotels
- Bostonia Hotels
- Crest Hotels
- Granite Hills Hotels
Adult Only Hotels & Resorts in other Cities
- Adult Only Hotels in Orlando
- Adult Only Hotels in Myrtle Beach
- Adult Only Hotels in South Padre
- Adult Only Hotels in Seven Mile
- Adult Only Hotels in Destin
- Adult Only Hotels in Wisconsin Dells
- Adult Only Hotels in Florida Keys
- Adult Only Hotels in Dallas
- Adult Only Hotels in Cancun
- Adult Only Hotels in St John
- Adult Only Hotels in Houston
- Adult Only Hotels in Miami Beach
- Adult Only Hotels in New York
- Adult Only Hotels in Cozumel
- Adult Only Hotels in Bora Bora
- Adult Only Hotels in Pensacola
- Adult Only Hotels in Michigan
- Adult Only Hotels in Georgia
- Adult Only Hotels in Lake Ozark
- Adult Only Hotels in Atlantic City
More ways to wander Downtown San Diego
Most popular
Hotels
- Hotels in Sorrento Valley
- Hotels in Carmel Valley
- Hotels in Liberty Station
- Point Loma Cheap Hotels
- Hotels in Mission Beach
- Gaslamp Quarter Hotels with Hot Tubs
- Hotels in Point Loma
- Hotels in Ocean Beach
- Hotels in Gaslamp Quarter
- Gaslamp Quarter Pet Friendly Hotels
- Hotels in Old Town San Diego
- Hotels in Mira Mesa
- Old Town San Diego Pet Friendly Hotels
- Hotels in Rancho Bernardo
- Hotels in Miramar
- Gaslamp Quarter Cheap Hotels
- Hotels in Pacific Beach
- Pacific Beach Beach Resorts & Hotels
- Hotels in Mission Valley
- Hotels in Bankers Hill
- Little Italy Cheap Hotels
- Ocean Beach Pet Friendly Hotels
Cars
Packages