Cheap Flights to Santa Cruz from $142 (2026/2027)

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A woman sitting on a beach facing the ocean with a sea turtle nearby.

Puerto Ayora

Flights
Puerto Ayora
A tortoise in a lush green forest.

Santa Rosa

Flights
Santa Rosa

How Much Does it Cost To Fly To Santa Cruz?

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Sat, Nov 14 - Tue, Nov 17
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$266 Roundtrip, found 8 hours ago
$266
Roundtrip
found 8 hours ago
Select avianca flight, departing Sat, Nov 14 from Jose Joaquin de Olmedo Intl. to San Cristobal, returning Tue, Nov 17, priced at $266 found 8 hours ago
Sat, Oct 17 - Wed, Oct 21
GYE
Jose Joaquin de Olmedo Intl.
SCY
San Cristobal
$285 Roundtrip, just found
$285
Roundtrip
just found
Select LATAM Airlines Group flight, departing Sat, Oct 17 from Jose Joaquin de Olmedo Intl. to San Cristobal, returning Wed, Oct 21, priced at $285 just found
Thu, Oct 22 - Mon, Oct 26
UIO
Mariscal Sucre Intl.
SCY
San Cristobal
$291 Roundtrip, found 1 hour ago
$291
Roundtrip
found 1 hour ago
Select avianca flight, departing Thu, Oct 22 from Mariscal Sucre Intl. to San Cristobal, returning Mon, Oct 26, priced at $291 found 1 hour ago
Fri, Apr 9 - Fri, Apr 16
UIO
Mariscal Sucre Intl.
GPS
Seymour
$308 Roundtrip, found 10 hours ago
$308
Roundtrip
found 10 hours ago
Select LATAM Airlines Group flight, departing Fri, Apr 9 from Mariscal Sucre Intl. to Seymour, returning Fri, Apr 16, priced at $308 found 10 hours ago
Sat, Jan 9 - Tue, Jan 12
GYE
Jose Joaquin de Olmedo Intl.
GPS
Seymour
$311 Roundtrip, found 12 hours ago
$311
Roundtrip
found 12 hours ago
Select LATAM Airlines Group flight, departing Sat, Jan 9 from Jose Joaquin de Olmedo Intl. to Seymour, returning Tue, Jan 12, priced at $311 found 12 hours ago
Fri, Oct 16 - Tue, Oct 20
MIA
Miami Intl.
SCY
San Cristobal
$541 Roundtrip, found 6 days ago
$541
Roundtrip
found 6 days ago
Select avianca flight, departing Fri, Oct 16 from Miami Intl. to San Cristobal, returning Tue, Oct 20, priced at $541 found 6 days ago
Tue, Nov 24 - Tue, Dec 1
BOS
Logan Intl.
SCY
San Cristobal
$559 Roundtrip, found 6 days ago
$559
Roundtrip
found 6 days ago
Select avianca flight, departing Tue, Nov 24 from Logan Intl. to San Cristobal, returning Tue, Dec 1, priced at $559 found 6 days ago
Thu, Dec 3 - Fri, Dec 11
BOS
Logan Intl.
GPS
Seymour
$592 Roundtrip, found 4 days ago
$592
Roundtrip
found 4 days ago
Select avianca flight, departing Thu, Dec 3 from Logan Intl. to Seymour, returning Fri, Dec 11, priced at $592 found 4 days ago
OriginDestinationTravel DatesFlights From*
UIOPuerto Baquerizo MorenoOctober 22 to October 26$291
UIOSanta RosaOctober 23 to October 27$308
LIMSanta RosaNovember 20 to November 24$500
LIMPuerto Baquerizo MorenoDecember 1 to December 4$574
MIASanta RosaOctober 24 to October 28$604
JFKPuerto Baquerizo MorenoDecember 3 to December 10$617
YYZPuerto Baquerizo MorenoNovember 12 to November 18$634
JFKSanta RosaDecember 3 to December 10$650
YYZSanta RosaJanuary 20 to January 27$666
LAXSanta RosaNovember 16 to November 23$844
IAHPuerto Baquerizo MorenoNovember 13 to November 25$911
IAHSanta RosaNovember 23 to November 27$924
ATLSanta RosaNovember 5 to November 8$1,186
LAXPuerto Baquerizo MorenoDecember 4 to December 11$1,261
ATLPuerto Baquerizo MorenoJanuary 14 to January 19$1,662
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
GYEPuerto Baquerizo MorenoOctober 11 to October 14$300
GYESanta RosaOctober 10 to October 15$329
UIOPuerto Baquerizo MorenoOctober 11 to October 17$338
UIOSanta RosaOctober 11 to October 17$364
JFKSanta RosaOctober 11 to October 16$766
LAXSanta RosaOctober 11 to October 19$844
JFKPuerto Baquerizo MorenoOctober 11 to October 15$886
IAHSanta RosaOctober 11 to October 19$944
LAXPuerto Baquerizo MorenoOctober 11 to October 19$1,639
*Prices include taxes and fees

Best Santa Cruz Flight and Hotel Packages

Price found within the past 48 hours. Click for updated prices.
BAY VIEW HOUSE
3.5-star property

BAY VIEW HOUSE

Nov 16 - Nov 19

3 night stay

Guayaquil (GYE) to Isla Baltra (GPS)

LATAM Airlines Group • Roundtrip • Coach
Price was $825, price is now $528 per person
$528
per person
found 1 day ago
Galapagos Native
3.0-star property

Galapagos Native

Oct 17 - Oct 21

4 night stay

Guayaquil (GYE) to Isla Baltra (GPS)

Avianca • Roundtrip • Coach
Price was $808, price is now $555 per person
$555
per person
found 1 day ago
Hotel y Restaurante Miconia
3.0-star property

Hotel y Restaurante Miconia

Oct 23 - Oct 27

4 night stay

Guayaquil (GYE) to San Cristobal (SCY)

Avianca • Roundtrip • Coach
Price was $722, price is now $530 per person
$530
per person
found 1 day ago
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Travelers ❤️ These Santa Cruz 🏨

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
Stay at this hotel in Puerto Ayora. Enjoy free WiFi, 3 hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Las Ninfas Lagoon and Malecon are located nearby.
9/10 Wonderful! (446 reviews)
"Beautiful pool and hot tub. Shower outside to use after swimming. Small bar beside pool. Nice eating area for brunch breakfast."

Reviewed on Oct 7, 2026

Opens in a new windowHotel Fiesta
Hotel el descanso del Guia

Hotel el descanso del Guia

3.5 out of 5
Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos
Book a stay at this family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions Las Ninfas Lagoon and Fishing Piers are located nearby.
Opens in a new windowHotel el descanso del Guia
Maidith Galapagos Inn

Maidith Galapagos Inn

3 out of 5
Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
Book a stay at this family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Fishing Piers and Gus Angermeyer Ferry Terminal are located nearby.
10/10 Exceptional! (167 reviews)
"El Servicio es excelentem"

Reviewed on Oct 5, 2026

Opens in a new windowMaidith Galapagos Inn
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Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

4.5 out of 5
Barrio Punta Estrada Puerto Ayora Galapagos
Book a stay at this luxury hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions Playa de los Alemanes and Malecon are located nearby.
Opens in a new windowFinch Bay Galapagos Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.