Cheap Flights to Mississippi County from $99 (2026/2027)

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A tree-lined landscape with a river and fields.

East Prairie

Flights
East Prairie

How Much Does it Cost To Fly To Mississippi County?

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Sat, Oct 31 - Sat, Nov 7
ORD
O'Hare Intl.
PAH
Barkley Regional
$194 Roundtrip, found 1 day ago
$194
Roundtrip
found 1 day ago
Select United flight, departing Sat, Oct 31 from O'Hare Intl. to Barkley Regional, returning Sat, Nov 7, priced at $194 found 1 day ago
Sat, Nov 14 - Tue, Nov 17
ORD
O'Hare Intl.
CGI
Cape Girardeau Municipal
$198 Roundtrip, found 8 hours ago
$198
Roundtrip
found 8 hours ago
Select Contour Airlines flight, departing Sat, Nov 14 from O'Hare Intl. to Cape Girardeau Municipal, returning Tue, Nov 17, priced at $198 found 8 hours ago
Tue, Dec 22 - Mon, Jan 4
ORD
O'Hare Intl.
CGI
Cape Girardeau Municipal
$218 Roundtrip, found 21 hours ago
$218
Roundtrip
found 21 hours ago
Select Contour Airlines flight, departing Tue, Dec 22 from O'Hare Intl. to Cape Girardeau Municipal, returning Mon, Jan 4, priced at $218 found 21 hours ago
Fri, Dec 18 - Sun, Dec 27
ORD
O'Hare Intl.
CGI
Cape Girardeau Municipal
$228 Roundtrip, found 3 days ago
$228
Roundtrip
found 3 days ago
Select Contour Airlines flight, departing Fri, Dec 18 from O'Hare Intl. to Cape Girardeau Municipal, returning Sun, Dec 27, priced at $228 found 3 days ago
Sat, Oct 31 - Sat, Nov 7
ORD
O'Hare Intl.
PAH
Barkley Regional
$234 Roundtrip, found 1 day ago
$234
Roundtrip
found 1 day ago
Select United flight, departing Sat, Oct 31 from O'Hare Intl. to Barkley Regional, returning Sat, Nov 7, priced at $234 found 1 day ago
Thu, Jan 14 - Tue, Jan 19
ORD
O'Hare Intl.
CGI
Cape Girardeau Municipal
$238 Roundtrip, found 1 day ago
$238
Roundtrip
found 1 day ago
Select Contour Airlines flight, departing Thu, Jan 14 from O'Hare Intl. to Cape Girardeau Municipal, returning Tue, Jan 19, priced at $238 found 1 day ago
Wed, Dec 23 - Sun, Dec 27
ORD
O'Hare Intl.
CGI
Cape Girardeau Municipal
$248 Roundtrip, found 6 days ago
$248
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Wed, Dec 23 from O'Hare Intl. to Cape Girardeau Municipal, returning Sun, Dec 27, priced at $248 found 6 days ago
Fri, Nov 6 - Sun, Nov 8
DFW
Dallas-Fort Worth Intl.
CGI
Cape Girardeau Municipal
$258 Roundtrip, found 10 hours ago
$258
Roundtrip
found 10 hours ago
Select Contour Airlines flight, departing Fri, Nov 6 from Dallas-Fort Worth Intl. to Cape Girardeau Municipal, returning Sun, Nov 8, priced at $258 found 10 hours ago
OriginDestinationTravel DatesFlights From*
ORDWest PaducahNovember 20 to November 23$194
ORDWest PaducahNovember 20 to November 23$194
ORDScott CityNovember 3 to November 5$198
ORDScott CityNovember 3 to November 5$198
MKEWest PaducahJanuary 6 to January 10$324
MCOWest PaducahNovember 10 to November 11$572
JFKScott CityDecember 23 to January 2$1,381
*Prices include taxes and fees

Best Mississippi County Flight and Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Super 8 by Wyndham Poplar Bluff Missouri
2.0-star property

Super 8 by Wyndham Poplar Bluff Missouri

Nov 12 - Nov 15

3 night stay

Detroit (DTW) to Cape Girardeau (CGI)

Southwest Airlines • Coach

Cape Girardeau (CGI) to Detroit (DTW)

Frontier Airlines • Coach
Price was $416, price is now $391 per person
$391
per person
found 11 hours ago
Hampton Inn Poplar Bluff
2.5-star property

Hampton Inn Poplar Bluff

Nov 12 - Nov 15

3 night stay

Detroit (DTW) to Cape Girardeau (CGI)

Southwest Airlines • Coach

Cape Girardeau (CGI) to Detroit (DTW)

Frontier Airlines • Coach
Price was $463, price is now $439 per person
$439
per person
found 11 hours ago
Days Inn by Wyndham Oak Grove/Ft. Campbell
2.5-star property

Days Inn by Wyndham Oak Grove/Ft. Campbell

Oct 23 - Oct 25

2 night stay

Tampa (TPA) to Paducah (PAH)

Southwest Airlines • Coach

Paducah (PAH) to Tampa (TPA)

Frontier Airlines • Coach
Price was $581, price is now $570 per person
$570
per person
found 1 day ago
Don't see what you're looking for?
See all available trips from Detroit to Mississippi County
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Travelers ❤️ These Mississippi County 🏨

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

2.5 out of 5
102 Drake St Charleston MO
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our reviews.
6.8/10 (442 reviews)
"Our stay was good. The staff was excellent, informative, and helpful; always had a smile on their faces."

Reviewed on Oct 16, 2026

Opens in a new windowThe Riverstone Hotel Charleston-Sikeston
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St Charleston MO
Stay at this motel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
Opens in a new windowSuper 8 by Wyndham Charleston/Sikeston East MO
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Central Park and Sikeston Depot Museum are located nearby.
9.6/10 Exceptional! (1,005 reviews)
"Great service."

Reviewed on Oct 19, 2026

Opens in a new windowDrury Inn & Suites Sikeston, MO
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Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Central Park and Sikeston Depot Museum are located nearby.
Opens in a new windowDays Inn and Suites by Wyndham Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much is the cheapest flight to Mississippi County?
Within the last seven days, the cheapest roundtrip flight to Mississippi County cost $194 on our site. Search through our unbeatable deals, make a booking and prepare for your next getaway. This price was available on Travelocity for flights to Mississippi County departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly to Mississippi County?
October is the cheapest month to jet to Mississippi County based on Travelocity's direct return flight demand between January and December last year. We'll help you bag an incredible deal so you can start preparing your itinerary today.
How can I check my flight status to Mississippi County?
Whether you'd like to view the status of your flight to Mississippi County or make changes to your itinerary, you'll find all the necessary details on our customer portal, Trips. Click on "Trips" at the top of our homepage, then sign in or create an account. Another convenient way to view and manage all your bookings is with the Travelocity app. Get real-time advice like flight status alerts and quickly share updates with any family flying with you.
How do I find the best deals on flights to Mississippi County?
There are a few ways — book in advance, avoid peak season and be flexible with your travel dates. If your dates aren't set in stone, search for your flight to Mississippi County on Travelocity and click on "Flexible dates" at the top of the page. This will help you locate any cheaper tickets on a nearby day. $194 was the lowest price paid for a roundtrip flight to Mississippi County in the last seven days. This price was available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Why should I book my flight to Mississippi County with Travelocity?
Pack your suitcase and get set for an epic trip with Travelocity. We'll help you find great deals on cheap flights to Mississippi County. Whether you're looking for flexible airfares with plenty of room to move or cheap family flights on low-cost airlines, we've got what you need.
What are the most popular flight routes to Mississippi County?
If you have plans to jump on a flight to Mississippi County, here are some leading routes to look into:

  • Chicago, IL (ORD-O'Hare Intl.) to Nashville Intl. Airport (BNA) - 2,491 flights a month.
  • Atlanta, GA (ATL-Hartsfield-Jackson Atlanta Intl.) to Nashville Intl. Airport (BNA) - 1,932 flights a month.
  • New York, NY (LGA-LaGuardia) to Nashville Intl. Airport (BNA) - 1,911 flights a month.

How much is a flight to Mississippi County on average?
Travelers have booked roundtrip flights to Mississippi County for between $194 and $1,381 with Travelocity in the last seven days. Whether you'd like to fly budget or first class, we'll help you get your hands on an awesome deal. These prices were available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
How long is the average flight to Mississippi County?
To get a feel for the average time of a direct flight to Mississippi County, take a peek at these popular routes:

  • Chicago, IL (ORD-O'Hare Intl.) to Nashville Intl. Airport (BNA) - 1 hour and 34 minutes
  • Atlanta, GA (ATL-Hartsfield-Jackson Atlanta Intl.) to Nashville Intl. Airport (BNA) - 1 hour and 5 minutes
  • New York, NY (LGA-LaGuardia) to Nashville Intl. Airport (BNA) - 2 hours and 26 minutes

What can I expect on a flight to Mississippi County?
How long your flight takes and whether you go with a low-priced or full-service carrier will largely determine this. If you're seeking long-haul flights to Mississippi County, drinks, food and entertainment are routine inclusions. After cheap flights for family vacations? Look up the fares from low-cost carriers. These airlines typically don't provide as many inclusions, so be prepared to pay for your drinks and meals.