Explore 4 Luxury Hotels in Clayton
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Best Luxury Hotels in Clayton
The Ritz-Carlton, St. Louis
100 Carondelet Plaza St. Louis MO
$499 nightly
The price is $583 total per night from May 10 to May 11
$583 total
May 10 - May 11
Total with taxes and fees
This smoke-free hotel's 2 restaurants, 3 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (566 reviews)
When we arrived it was really loud hard to hear customer service as karaoke was going on.
Reviewed on Apr 27, 2026
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
$105 nightly
The price is $122 total per night from May 17 to May 18
$122 total
May 17 - May 18
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (3,181 reviews)
Great breakfast, Room was spectacular, Parking Garage was a huge plus.
Reviewed on May 3, 2026
Le Méridien St. Louis Clayton
7730 Bonhomme Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $169 total per night from May 10 to May 11
$169 total
May 10 - May 11
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.8/10 Excellent! (712 reviews)
It was good but there is just one problem of parking and they charge for patking 35 bucks
Reviewed on Apr 28, 2026
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
26 North Meramec Avenue St. Louis MO
$166 nightly
The price is $194 total per night from May 24 to May 25
$194 total
May 24 - May 25
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the 2 conference rooms, free WiFi in public areas, and express ...
8.4/10 Very Good! (588 reviews)
No USB port in my room!!!
Reviewed on Apr 19, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More 4 star hotels in Clayton
Moonrise Hotel
6177 Delmar Blvd St. Louis MO
$174 nightly
The price is $206 total per night from May 10 to May 11
$206 total
May 10 - May 11
Total with taxes and fees
9/10 Wonderful! (1,928 reviews)
5 star hotels in Clayton
Four Seasons Hotel St Louis
999 North Second Street St. Louis MO
$335 nightly
The price is $392 total per night from May 6 to May 7
$392 total
May 6 - May 7
Total with taxes and fees
9.4/10 Exceptional! (1,001 reviews)
Clayton Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Clayton luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Clayton to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Clayton will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Clayton, and plan your next opulent escape.
Clayton hotels essential information
Accommodation | 1,902 hotels |
|---|---|
Lowest Price | $122 |
Highest Price | $583 |
Popular hotels | The Ritz-Carlton, St. Louis, Clayton Plaza Hotel & Extended Stay, Le Méridien St. Louis Clayton, Seven Gables, St. Louis West, a Tribute Portfolio Hotel |
Popular Luxury Stays in Clayton
Recent Clayton Hotel Reviews By Fellow Wanderers
Hyatt Regency St. Louis at The Arch
5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"It was a nice place and nice easy walk to the ballpark"
A verified traveler stayed at Hyatt Regency St. Louis at The Arch
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