Explore top 2026 5 Star Hotels in Eastern Sicily

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Top Eastern Sicily 5 Star hotels

Mazzarò Sea Palace - The Leading Hotels of the World

Mazzarò Sea Palace - The Leading Hotels of the World

5 out of 5
Via Nazionale 147 Taormina ME
Fully refundableReserve now, pay when you stay
$1,188 nightly
The price is $1,318 total per night from Jun 8 to Jun 9
$1,318 total
Jun 8 - Jun 9
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
9.6/10 Exceptional! (299 reviews)
"Stunning hotel, beautiful location and beach. Amazing place to stay in Taormina."

Reviewed on May 6, 2026

Opens in a new windowMazzarò Sea Palace - The Leading Hotels of the World
Atlantis Bay - The Leading Hotel of the World

Atlantis Bay - The Leading Hotel of the World

5 out of 5
Via Nazionale 161 Taormina ME
Fully refundableReserve now, pay when you stay
$889 nightly
The price is $989 total per night from Jun 14 to Jun 15
$989 total
Jun 14 - Jun 15
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center and free ...
9.6/10 Exceptional! (478 reviews)
"Great location"

Reviewed on May 20, 2026

Opens in a new windowAtlantis Bay - The Leading Hotel of the World
Romano Palace Luxury Hotel

Romano Palace Luxury Hotel

5 out of 5
Viale Kennedy 28 Catania CT
Fully refundableReserve now, pay when you stay
$150 nightly
The price is $176 total per night from May 31 to Jun 1
$176 total
May 31 - Jun 1
Total with taxes and fees
This hotel features a restaurant, a seasonal outdoor pool, and a bar/lounge. Families will appreciate the onsite laundry facilities, kid-friendly dining, and ...
7.8/10 Good! (968 reviews)
"Room Tired and needs uplift - paintwork, shower handle loose. Staff friendly and helpful. Great variety at breakfast. Restaurant a bit pricey."

Reviewed on May 14, 2026

Opens in a new windowRomano Palace Luxury Hotel
Grand Hotel Timeo, A Belmond Hotel, Taormina

Grand Hotel Timeo, A Belmond Hotel, Taormina

5 out of 5
Via Teatro Greco 59 Taormina ME
$2,209 nightly
The price is $2,442 total per night from May 29 to May 30
$2,442 total
May 29 - May 30
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Opens in a new windowGrand Hotel Timeo, A Belmond Hotel, Taormina
Villa Sant'Andrea, A Belmond Hotel, Taormina Mare

Villa Sant'Andrea, A Belmond Hotel, Taormina Mare

5 out of 5
Via Nazionale, 137 Taormina ME
$2,221 nightly
The price is $2,454 total per night from Jun 21 to Jun 22
$2,454 total
Jun 21 - Jun 22
Total with taxes and fees
This smoke-free hotel features a private beach, a full-service spa, and a restaurant. There's fun for all ages with a children's club and a playground, and in-room ...
9.4/10 Exceptional! (138 reviews)
"Staff friendliness. Everyone was extremely helpful. Family owned experience. Hotel rooms were clean. Housekeeping was beyond satisfactory. Timeless luxury is the perfect definition for the entire experience."

Reviewed on May 15, 2026

Opens in a new windowVilla Sant'Andrea, A Belmond Hotel, Taormina Mare
San Domenico Palace, Taormina, A Four Seasons Hotel

San Domenico Palace, Taormina, A Four Seasons Hotel

5 out of 5
PIAZZA SAN DOMENICO, 5 Taormina ME
$3,280 nightly
The price is $3,619 total per night from May 25 to May 26
$3,619 total
May 25 - May 26
Total with taxes and fees
A full-service spa, 3 restaurants, and a 24-hour gym are all featured at this luxury hotel. Families will appreciate the picnic area and in-room childcare. Enjoy ...
Opens in a new windowSan Domenico Palace, Taormina, A Four Seasons Hotel
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

5 out of 5
Viale Mazzini, 12 Syracuse SR
Fully refundableReserve now, pay when you stay
$308 nightly
The price is $351 total per night from May 31 to Jun 1
$351 total
May 31 - Jun 1
Total with taxes and fees
This hotel features a restaurant, a rooftop terrace, and a bar/lounge. Take the beach shuttle and relax with sun loungers and beach umbrellas. WiFi in public ...
9/10 Wonderful! (593 reviews)
"We stayed here for two nights and were extremely disappointed, especially considering this is supposed to be a five star property. Our first night we were put in a room where the bathroom had a horrid smell that spread to the entire room. The room was also on the same floor as all the cleaning staff ..."

Reviewed on May 17, 2026

Opens in a new windowGrand Hotel Ortigia Siracusa
Mangia's Brucoli, Sicily, Autograph Collection

Mangia's Brucoli, Sicily, Autograph Collection

5 out of 5
Contrada Gisira 1 Augusta SR
Fully refundableReserve now, pay when you stay
$188 nightly
The price is $213 total per night from Jun 7 to Jun 8
$213 total
Jun 7 - Jun 8
Total with taxes and fees
This luxury hotel features 5 restaurants, 3 outdoor pools, and a gym. Bring the family and enjoy the free kid's club, children's pool, and playground. Relax ...
8.6/10 Excellent! (125 reviews)
"Nice location, very friendly staff, Breakfast was especially good"

Reviewed on May 10, 2026

Opens in a new windowMangia's Brucoli, Sicily, Autograph Collection
Palazzo Sangiorgio

Palazzo Sangiorgio

5 out of 5
Via Cardinale Pappalardo, 1 Catania CT
Fully refundableReserve now, pay when you stay
$307 nightly
The price is $350 total per night from Jun 2 to Jun 3
$350 total
Jun 2 - Jun 3
Total with taxes and fees
A full-service spa, a hot tub, and a restaurant are all featured at this luxury hotel. Business travelers can take advantage of the free WiFi in public areas. ...
9.8/10 Exceptional! (173 reviews)
"Wonderful staff and what a great room with Jacuzzi!!"

Reviewed on May 18, 2026

Opens in a new windowPalazzo Sangiorgio
Grand Hotel San Pietro Taormina - Preferred Hotels & Resorts

Grand Hotel San Pietro Taormina - Preferred Hotels & Resorts

5 out of 5
Via Pirandello, 50 Taormina ME
Fully refundableReserve now, pay when you stay
$969 nightly
The price is $1,077 total per night from May 27 to May 28
$1,077 total
May 27 - May 28
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public areas, ...
Opens in a new windowGrand Hotel San Pietro Taormina - Preferred Hotels & Resorts
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Eastern Sicily Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Eastern Sicily to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Eastern Sicily 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Eastern Sicily before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Eastern Sicily hotel reviews by fellow wanderers