Explore top 2026 4 Star Hotels in Mesopotamia

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Top Mesopotamia 4 Star hotels

Amérian Hotel Casino Gala

Amérian Hotel Casino Gala

4 out of 5
Juan Domingo Perón 330 esq. Necochea Resistencia Chaco
Fully refundableReserve now, pay when you stay
A casino and an outdoor pool are featured at this smoke-free hotel. Enjoy a meal from the restaurant and perks like free buffet breakfast and free WiFi. Luggage ...
9/10 Wonderful! (164 reviews)
Good check in

Reviewed on Dec 1, 2025

Opens in a new windowAmérian Hotel Casino Gala
Esplendor by Wyndham Savoy Rosario

Esplendor by Wyndham Savoy Rosario

4 out of 5
San Lorenzo 1022 Rosario Santa Fe
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $96 total per night from Jan 2 to Jan 3
$96 total
Jan 2 - Jan 3, 2026
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the seasonal ...
8.4/10 Very Good! (443 reviews)
El desayuno fue variado, no pude acceder a la pileta.

Reviewed on Oct 20, 2025

Opens in a new windowEsplendor by Wyndham Savoy Rosario
Marriott Corrientes Hotel

Marriott Corrientes Hotel

4.5 out of 5
Av Costanera Juan Pablo II y Lavalle Corrientes
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $125 total per night from Dec 19 to Dec 20
$125 total
Dec 19 - Dec 20
Book a stay at this luxury hotel in Corrientes. Popular attractions Costanera de Corrientes and Cumba Cua Park are located nearby.
10/10 Exceptional! (4 reviews)
Very nice hotel

Reviewed on Nov 9, 2025

Opens in a new windowMarriott Corrientes Hotel
Dazzler by Wyndham Rosario

Dazzler by Wyndham Rosario

4 out of 5
Junin 187 Rosario Santa Fe
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $94 total per night from Dec 10 to Dec 11
$94 total
Dec 10 - Dec 11
This hotel features an outdoor pool, a hot tub, and a restaurant. Enjoy the gym and free perks like full breakfast and WiFi in public areas. There's a bar/lounge ...
8.6/10 Excellent! (187 reviews)
Convenient if you like shopping and the hotel very good amenities

Reviewed on Oct 26, 2025

Opens in a new windowDazzler by Wyndham Rosario
InterTower Hotel

InterTower Hotel

4 out of 5
San Jeronimo 2779 Santa Fe Santa Fe
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $92 total per night from Dec 28 to Dec 29
$92 total
Dec 28 - Dec 29
A full-service spa, an outdoor pool, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the 24-hour business ...
8.8/10 Excellent! (210 reviews)
Very good

Reviewed on Nov 20, 2025

Opens in a new windowInterTower Hotel
Puerto Norte Design Hotel

Puerto Norte Design Hotel

4 out of 5
Av Luis Candido Carballo 148 Rosario Santa Fe
Fully refundableReserve now, pay when you stay
A full-service spa, an outdoor pool, and a restaurant are all featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi ...
9/10 Wonderful! (142 reviews)
Super comfortable and luxurious with amazing view of the river. The staff was courteous enough and parking was easy and right in front of the hotel.

Reviewed on Dec 30, 2024

Opens in a new windowPuerto Norte Design Hotel
Los Silos Hotel

Los Silos Hotel

4 out of 5
Dique I Puerto Santa Fe Santa Fe Santa Fe
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $116 total per night from Dec 14 to Dec 15
$116 total
Dec 14 - Dec 15
This smoke-free hotel features a casino, a full-service spa, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy ...
9.2/10 Wonderful! (27 reviews)
Muy original, un hotel construido en un viejo Silo

Reviewed on Mar 31, 2024

Opens in a new windowLos Silos Hotel
Pullman Rosario City Center Hotel

Pullman Rosario City Center Hotel

4 out of 5
Av Batlle Y Ordoñez Y Bv Oroño Rosario Santa Fe
This Beaux Arts hotel features a casino, a full-service spa, and a nightclub. There's fun for all ages with a playground and an arcade/game room, and families ...
8.4/10 Very Good! (273 reviews)
Nice

Reviewed on Aug 13, 2025

Opens in a new windowPullman Rosario City Center Hotel
Ros Tower Hotel

Ros Tower Hotel

4 out of 5
Mitre 299 Rosario Santa Fe
A full-service spa and an outdoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, laundry service, ...
8.6/10 Excellent! (312 reviews)
Everything ok, people very friendly

Reviewed on Sep 7, 2025

Opens in a new windowRos Tower Hotel
La Alondra Casa De Huéspedes

La Alondra Casa De Huéspedes

4 out of 5
Av. 3 De Abril 827 Corrientes Corrientes
This guesthouse features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9.2/10 Wonderful! (64 reviews)
Very nice place in the middle of the city to be quiet, eat delicious, sunbathe. They should improve some minor issues to have a more than excellent stay.

Reviewed on Dec 21, 2020

Opens in a new windowLa Alondra Casa De Huéspedes
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4 Star Hotels Mesopotamia

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Mesopotamia 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Mesopotamia will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Mesopotamia, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Mesopotamia hotel reviews by fellow wanderers