Santiago Island Vacation Packages 2025/2026 from $425

Santiago Island flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Hotel Cally Galapagos

per person

Sep 6 - Sep 11

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

A full-service spa and a restaurant are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. A bar/lounge, a terrace, and express check-in are also provided.

Royal Palm Galapagos, Curio Collection Hotel by Hilton

Save 100% on your flight

per person

Sep 6 - Sep 11

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

This luxury hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. You'll appreciate the gym, bar/lounge, and laundry facilities.

Hotel Flamingo

per person

Sep 6 - Sep 11

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

This hotel features a rooftop terrace and a hot tub. Relax with a drink at the bar/lounge and enjoy free perks like continental breakfast and free self parking. Free WiFi in public areas, a terrace, and a garden are also on offer.

Hotel el descanso del Guia

per person

Aug 12 - Aug 17

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Bring the family and enjoy the children's pool, playground, and arcade/game room. Enjoy the 24-hour gym and free perks like continental breakfast and WiFi in public areas.

Angermeyer Waterfront Inn

Save 100% on your flight

per person

Sep 6 - Sep 11

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

A marina and a restaurant are featured at this smoke-free hotel. Enjoy the a rooftop terrace and perks like free WiFi. There's a bar/lounge on site, and laundry facilities and concierge services are also provided.

Top Santiago Island hotels deals

Hostal cielo azul

Puerto Villamil Pedregal 1, Bella Vista, Islas Galápagos

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Free WiFi in public areas and a safe deposit box are available at this hostal. Staff at the 24-hour front desk can provide around-the-clock assistance.

Free WiFi

24/7 front desk

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Mosquera Island

4/5(1 review)

Commune with nature and explore the great outdoors at Mosquera Island during your travels in Santiago Island. While you're in the area, wander around the parks.

Puerto Egas

Learn about the local history of Santiago Island with a stop at Puerto Egas. While you're in the area, wander around the natural setting.

Frequently asked questions

How much are vacation packages to Santiago Island?

Adventures are calling in Santiago Island, with Travelocity vacation packages starting from just $425. In addition to flights and hotels, these terrific deals make it easy to experience more of our wonderful planet.

Where can I get the best vacation package deals for Santiago Island?

It's hard to look past Travelocity when it comes to piecing together your Santiago Island package deal. There are at least 400 partner airlines and 1,000,000 properties worldwide to select from. Secure your trip now and get ready to cross another exciting destination off your to-do list.

Why should I book my Santiago Island vacation package with Travelocity?

From our 24/7 customer care to our range of terrific destinations, we are dedicated to giving you the most unforgettable vacation. All you have to do is click and book --- our Price Match Guarantee will ensure you score the best price.

Will I save money on my Santiago Island car rental if I book it with my hotel or flight?

Sure can. And our Santiago Island vacation packages will help you do it. In just a few clicks you can save money as well as time by combining your bookings. Collect the keys to your rental car then set your own course. Need to fill your itinerary? Add some activities or experiences to your package and make savings on those too.

What is there to do in Santiago Island?

Mosquera Island is one of the awesome sights that make Santiago Island a popular place to visit. But give yourself enough time to discover its lesser-known attractions too. This is often where the best memories are made.