UA5386 takes multiple routes. The most popular is Reno, NV (RNO-Reno-Tahoe Intl.) to Denver, CO (DEN-Denver Intl.), which is a direct flight. This service takes roughly 2 hours and 12 minutes. However, you might find other flights with this number that have one or more stops.
If you have a seat on flight UA5386 from Reno, NV (RNO-Reno-Tahoe Intl.) to Denver, CO (DEN-Denver Intl.), there's a good chance you'll be jetting off on the Embraer 175. This flight number serves a number of routes, but this is the most popular.