Delta Flight 5378 Deals & Information (2025/2026)

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Delta Flight 5378 Route Deals From $224

The cheapest prices found with in the last 7 days for return flights were $305 and $224 for one-way flights to Evansville Regional for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

What route does flight number DL5378 take?
Flight number DL5378 flies direct from Detroit, MI Airport (DTW-Detroit Metropolitan Wayne County) to Cleveland, OH Airport (CLE-Hopkins Intl.). During this journey, you can expect to be in the air for roughly 51 minutes. It's wise to book ahead to secure your favorite seat.
What terminal does DL5378 fly out of?
You'll likely be taking off from Terminal EM if you're flying on DL5378 direct from Detroit, MI Airport (DTW-Detroit Metropolitan Wayne County) to CLE.
What kind of plane is on flight number DL5378?
You'll probably find yourself boarding the Bombardier CRJ900 if you're booked on flight number DL5378. This flight nearly always takes off from DTW and touches down at Cleveland Hopkins Intl. Airport.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your DL5378 flight with Travelocity, please visit our Customer Service Portal.