Delta Flight 5343 Deals & Information (2025/2026)

Wander Wisely with exceptional service, 24/7 supportOpens in a new window

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

Delta Flight 5343 Route Deals From $89

The cheapest prices found with in the last 7 days for return flights were $171 and $89 for one-way flights to LaGuardia for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Aug 1 - Mon, Aug 4
ROC
Greater Rochester Intl.
LGA
LaGuardia
$171 Roundtrip, found 5 days ago
$171
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, Aug 1 from Greater Rochester Intl. to LaGuardia, returning Mon, Aug 4, priced at $171 found 5 days ago
Tue, Aug 26 - Fri, Aug 29
ROC
Greater Rochester Intl.
LGA
LaGuardia
$179 Roundtrip, found 13 hours ago
$179
Roundtrip
found 13 hours ago
Select Delta flight, departing Tue, Aug 26 from Greater Rochester Intl. to LaGuardia, returning Fri, Aug 29, priced at $179 found 13 hours ago
Thu, Jul 31 - Sat, Aug 2
ROC
Greater Rochester Intl.
LGA
LaGuardia
$184 Roundtrip, found 4 days ago
$184
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Jul 31 from Greater Rochester Intl. to LaGuardia, returning Sat, Aug 2, priced at $184 found 4 days ago
Sat, Sep 6 - Mon, Sep 8
ROC
Greater Rochester Intl.
LGA
LaGuardia
$187 Roundtrip, found 4 days ago
$187
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Sep 6 from Greater Rochester Intl. to LaGuardia, returning Mon, Sep 8, priced at $187 found 4 days ago
Wed, Sep 3 - Sun, Sep 7
ROC
Greater Rochester Intl.
LGA
LaGuardia
$189 Roundtrip, found 3 hours ago
$189
Roundtrip
found 3 hours ago
Select Delta flight, departing Wed, Sep 3 from Greater Rochester Intl. to LaGuardia, returning Sun, Sep 7, priced at $189 found 3 hours ago
Sat, Sep 6 - Mon, Sep 8
ROC
Greater Rochester Intl.
LGA
LaGuardia
$197 Roundtrip, found 4 days ago
$197
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Sep 6 from Greater Rochester Intl. to LaGuardia, returning Mon, Sep 8, priced at $197 found 4 days ago
Fri, Aug 1 - Mon, Aug 4
ROC
Greater Rochester Intl.
LGA
LaGuardia
$201 Roundtrip, found 5 days ago
$201
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, Aug 1 from Greater Rochester Intl. to LaGuardia, returning Mon, Aug 4, priced at $201 found 5 days ago
Sat, Jan 17 - Mon, Jan 19
ROC
Greater Rochester Intl.
LGA
LaGuardia
$207 Roundtrip, found 1 day ago
$207
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Jan 17 from Greater Rochester Intl. to LaGuardia, returning Mon, Jan 19, priced at $207 found 1 day ago
Thu, Aug 7 - Sat, Aug 9
ROC
Greater Rochester Intl.
LGA
LaGuardia
$209 Roundtrip, found 8 hours ago
$209
Roundtrip
found 8 hours ago
Select Delta flight, departing Thu, Aug 7 from Greater Rochester Intl. to LaGuardia, returning Sat, Aug 9, priced at $209 found 8 hours ago
Fri, Aug 1 - Mon, Aug 4
ROC
Greater Rochester Intl.
LGA
LaGuardia
$213 Roundtrip, found 5 days ago
$213
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, Aug 1 from Greater Rochester Intl. to LaGuardia, returning Mon, Aug 4, priced at $213 found 5 days ago

Frequently asked questions

What route does flight number DL5343 take?
DL5343 takes 2 hours and 7 minutes to fly straight from Des Moines Intl. Airport (DSM) to Atlanta, GA Airport (ATL-Hartsfield-Jackson Atlanta Intl.). Sure, there's magic in the destination, but the journey is always half the fun!
What kind of plane is on flight number DL5343?
You'll likely be traveling aboard the Bombardier CRJ900 if you're on flight DL5343. This flight almost always heads off from DSM and arrives at Hartsfield–Jackson Atlanta International Airport.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your DL5343 flight with Travelocity, please visit our Customer Service Portal.