Delta Flight DL5321 Deals & Information (2025/2026)

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Delta Flight 5321 Route Deals From $182

The cheapest prices found with in the last 7 days for return flights were $239 and $182 for one-way flights to LaGuardia for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Nov 19 - Mon, Dec 8
ROA
Roanoke Regional
LGA
LaGuardia
$239 Roundtrip, found 12 hours ago
$239
Roundtrip
found 12 hours ago
Select Delta flight, departing Wed, Nov 19 from Roanoke Regional to LaGuardia, returning Mon, Dec 8, priced at $239 found 12 hours ago
Mon, Oct 20 - Thu, Nov 6
ROA
Roanoke Regional
LGA
LaGuardia
$244 Roundtrip, found 2 days ago
$244
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Oct 20 from Roanoke Regional to LaGuardia, returning Thu, Nov 6, priced at $244 found 2 days ago
Sat, Nov 1 - Sun, Nov 16
ROA
Roanoke Regional
LGA
LaGuardia
$249 Roundtrip, found 12 hours ago
$249
Roundtrip
found 12 hours ago
Select Delta flight, departing Sat, Nov 1 from Roanoke Regional to LaGuardia, returning Sun, Nov 16, priced at $249 found 12 hours ago
Sat, Oct 25 - Thu, Nov 6
ROA
Roanoke Regional
LGA
LaGuardia
$254 Roundtrip, found 2 days ago
$254
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Oct 25 from Roanoke Regional to LaGuardia, returning Thu, Nov 6, priced at $254 found 2 days ago
Thu, Oct 9 - Sat, Oct 25
ROA
Roanoke Regional
LGA
LaGuardia
$279 Roundtrip, found 2 days ago
$279
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Oct 9 from Roanoke Regional to LaGuardia, returning Sat, Oct 25, priced at $279 found 2 days ago
Fri, Oct 24 - Sat, Oct 25
ROA
Roanoke Regional
LGA
LaGuardia
$284 Roundtrip, found 2 days ago
$284
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Oct 24 from Roanoke Regional to LaGuardia, returning Sat, Oct 25, priced at $284 found 2 days ago
Sat, Nov 15 - Sat, Dec 6
ROA
Roanoke Regional
LGA
LaGuardia
$289 Roundtrip, found 12 hours ago
$289
Roundtrip
found 12 hours ago
Select Delta flight, departing Sat, Nov 15 from Roanoke Regional to LaGuardia, returning Sat, Dec 6, priced at $289 found 12 hours ago
Wed, Nov 19 - Tue, Nov 25
ROA
Roanoke Regional
LGA
LaGuardia
$297 Roundtrip, found 12 hours ago
$297
Roundtrip
found 12 hours ago
Select Delta flight, departing Wed, Nov 19 from Roanoke Regional to LaGuardia, returning Tue, Nov 25, priced at $297 found 12 hours ago
Sun, Nov 23 - Mon, Dec 8
ROA
Roanoke Regional
LGA
LaGuardia
$298 Roundtrip, found 12 hours ago
$298
Roundtrip
found 12 hours ago
Select Delta flight, departing Sun, Nov 23 from Roanoke Regional to LaGuardia, returning Mon, Dec 8, priced at $298 found 12 hours ago
Tue, Sep 9 - Mon, Oct 6
ROA
Roanoke Regional
LGA
LaGuardia
$304 Roundtrip, found 9 hours ago
$304
Roundtrip
found 9 hours ago
Select Delta flight, departing Tue, Sep 9 from Roanoke Regional to LaGuardia, returning Mon, Oct 6, priced at $304 found 9 hours ago
Mon, Oct 6 - Mon, Oct 20
ROA
Roanoke Regional
LGA
LaGuardia
$304 Roundtrip, found 2 days ago
$304
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Oct 6 from Roanoke Regional to LaGuardia, returning Mon, Oct 20, priced at $304 found 2 days ago
Fri, Oct 24 - Sun, Oct 26
ROA
Roanoke Regional
LGA
LaGuardia
$305 Roundtrip, found 2 days ago
$305
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Oct 24 from Roanoke Regional to LaGuardia, returning Sun, Oct 26, priced at $305 found 2 days ago
Sat, Nov 8 - Sun, Nov 23
ROA
Roanoke Regional
LGA
LaGuardia
$307 Roundtrip, found 12 hours ago
$307
Roundtrip
found 12 hours ago
Select Delta flight, departing Sat, Nov 8 from Roanoke Regional to LaGuardia, returning Sun, Nov 23, priced at $307 found 12 hours ago

Frequently asked questions

What route does flight number DL5321 take?
You'll arrive into Roger Milliken Field from Detroit, MI Airport (DTW-Detroit Metropolitan Wayne County) if you've booked a ticket on flight number DL5321. You'll be in the sky for 1 hour and 41 minutes during this journey. What's more, the service conveniently travels non-stop.
What terminal does DL5321 fly out of?
Travelers with a booking on flight number DL5321 from Metro Airport to Greenville-Spartanburg Intl. Airport (GSP) usually depart from Terminal EM.
What kind of plane is on flight number DL5321?
Get set to hop on board a Bombardier CRJ900 if you've booked a seat on flight DL5321. The majority of flights from DTW to Greenville, SC Airport (GSP-Greenville-Spartanburg Intl.) use this aircraft model.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your DL5321 flight with Travelocity, please visit our Customer Service Portal.