Delta Flight DL5321 Deals & Information (2025/2026)

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Delta Flight 5321 Route Deals From $182

The cheapest prices found with in the last 7 days for return flights were $243 and $182 for one-way flights to LaGuardia for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Aug 14 - Fri, Aug 29
ROA
Roanoke Regional
LGA
LaGuardia
$243 Roundtrip, found 3 days ago
$243
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Aug 14 from Roanoke Regional to LaGuardia, returning Fri, Aug 29, priced at $243 found 3 days ago
Thu, Sep 4 - Sun, Sep 7
ROA
Roanoke Regional
LGA
LaGuardia
$253 Roundtrip, found 3 days ago
$253
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Sep 4 from Roanoke Regional to LaGuardia, returning Sun, Sep 7, priced at $253 found 3 days ago
Fri, Sep 5 - Sun, Sep 7
ROA
Roanoke Regional
LGA
LaGuardia
$253 Roundtrip, found 1 day ago
$253
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Sep 5 from Roanoke Regional to LaGuardia, returning Sun, Sep 7, priced at $253 found 1 day ago
Thu, Sep 25 - Sat, Sep 27
ROA
Roanoke Regional
LGA
LaGuardia
$259 Roundtrip, found 19 hours ago
$259
Roundtrip
found 19 hours ago
Select Delta flight, departing Thu, Sep 25 from Roanoke Regional to LaGuardia, returning Sat, Sep 27, priced at $259 found 19 hours ago
Fri, Sep 5 - Sun, Sep 7
ROA
Roanoke Regional
LGA
LaGuardia
$263 Roundtrip, found 1 day ago
$263
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Sep 5 from Roanoke Regional to LaGuardia, returning Sun, Sep 7, priced at $263 found 1 day ago
Thu, Nov 20 - Fri, Dec 5
ROA
Roanoke Regional
LGA
LaGuardia
$269 Roundtrip, found 2 days ago
$269
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Nov 20 from Roanoke Regional to LaGuardia, returning Fri, Dec 5, priced at $269 found 2 days ago
Sat, Sep 6 - Sun, Sep 7
ROA
Roanoke Regional
LGA
LaGuardia
$283 Roundtrip, found 3 days ago
$283
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Sep 6 from Roanoke Regional to LaGuardia, returning Sun, Sep 7, priced at $283 found 3 days ago
Thu, Sep 25 - Sat, Sep 27
ROA
Roanoke Regional
LGA
LaGuardia
$289 Roundtrip, found 19 hours ago
$289
Roundtrip
found 19 hours ago
Select Delta flight, departing Thu, Sep 25 from Roanoke Regional to LaGuardia, returning Sat, Sep 27, priced at $289 found 19 hours ago
Mon, Aug 25 - Mon, Sep 8
ROA
Roanoke Regional
LGA
LaGuardia
$293 Roundtrip, found 4 days ago
$293
Roundtrip
found 4 days ago
Select Delta flight, departing Mon, Aug 25 from Roanoke Regional to LaGuardia, returning Mon, Sep 8, priced at $293 found 4 days ago
Sun, Aug 3 - Fri, Aug 15
ROA
Roanoke Regional
LGA
LaGuardia
$294 Roundtrip, found 3 days ago
$294
Roundtrip
found 3 days ago
Select Delta flight, departing Sun, Aug 3 from Roanoke Regional to LaGuardia, returning Fri, Aug 15, priced at $294 found 3 days ago
Fri, Dec 12 - Sun, Dec 14
ROA
Roanoke Regional
LGA
LaGuardia
$298 Roundtrip, found 2 days ago
$298
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, Dec 12 from Roanoke Regional to LaGuardia, returning Sun, Dec 14, priced at $298 found 2 days ago
Tue, Jul 29 - Tue, Aug 12
ROA
Roanoke Regional
LGA
LaGuardia
$302 Roundtrip, found 2 days ago
$302
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Jul 29 from Roanoke Regional to LaGuardia, returning Tue, Aug 12, priced at $302 found 2 days ago

Frequently asked questions

What route does flight number DL5321 take?
You'll arrive into Roger Milliken Field from Detroit, MI Airport (DTW-Detroit Metropolitan Wayne County) if you've booked a ticket on flight number DL5321. You'll be in the sky for 1 hour and 41 minutes during this journey. What's more, the service conveniently travels non-stop.
What terminal does DL5321 fly out of?
Travelers with a booking on flight number DL5321 from Metro Airport to Greenville-Spartanburg Intl. Airport (GSP) usually depart from Terminal EM.
What kind of plane is on flight number DL5321?
Get set to hop on board a Bombardier CRJ900 if you've booked a seat on flight DL5321. The majority of flights from DTW to Greenville, SC Airport (GSP-Greenville-Spartanburg Intl.) use this aircraft model.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your DL5321 flight with Travelocity, please visit our Customer Service Portal.