Delta Flight DL5321 Deals & Information (2025/2026)

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Delta Flight 5321 Route Deals From $249

The cheapest prices found with in the last 7 days for return flights were $315 and $249 for one-way flights to LaGuardia for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Sep 23 - Tue, Sep 30
ROA
Roanoke Regional
LGA
LaGuardia
$315 Roundtrip, found 2 days ago
$315
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Sep 23 from Roanoke Regional to LaGuardia, returning Tue, Sep 30, priced at $315 found 2 days ago
Tue, Jul 29 - Tue, Aug 5
ROA
Roanoke Regional
LGA
LaGuardia
$322 Roundtrip, found 8 hours ago
$322
Roundtrip
found 8 hours ago
Select Delta flight, departing Tue, Jul 29 from Roanoke Regional to LaGuardia, returning Tue, Aug 5, priced at $322 found 8 hours ago
Sat, Sep 27 - Tue, Sep 30
ROA
Roanoke Regional
LGA
LaGuardia
$325 Roundtrip, found 2 days ago
$325
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Sep 27 from Roanoke Regional to LaGuardia, returning Tue, Sep 30, priced at $325 found 2 days ago
Mon, Jun 30 - Sat, Jul 5
ROA
Roanoke Regional
LGA
LaGuardia
$333 Roundtrip, found 5 days ago
$333
Roundtrip
found 5 days ago
Select Delta flight, departing Mon, Jun 30 from Roanoke Regional to LaGuardia, returning Sat, Jul 5, priced at $333 found 5 days ago
Sat, Sep 27 - Sat, Oct 4
ROA
Roanoke Regional
LGA
LaGuardia
$335 Roundtrip, found 2 days ago
$335
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Sep 27 from Roanoke Regional to LaGuardia, returning Sat, Oct 4, priced at $335 found 2 days ago
Thu, Nov 20 - Tue, Nov 25
ROA
Roanoke Regional
LGA
LaGuardia
$335 Roundtrip, found 1 day ago
$335
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Nov 20 from Roanoke Regional to LaGuardia, returning Tue, Nov 25, priced at $335 found 1 day ago
Mon, Sep 29 - Sat, Oct 4
ROA
Roanoke Regional
LGA
LaGuardia
$340 Roundtrip, found 2 days ago
$340
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Sep 29 from Roanoke Regional to LaGuardia, returning Sat, Oct 4, priced at $340 found 2 days ago
Sun, Jul 27 - Tue, Aug 5
ROA
Roanoke Regional
LGA
LaGuardia
$342 Roundtrip, found 8 hours ago
$342
Roundtrip
found 8 hours ago
Select Delta flight, departing Sun, Jul 27 from Roanoke Regional to LaGuardia, returning Tue, Aug 5, priced at $342 found 8 hours ago
Wed, Jul 9 - Tue, Jul 22
ROA
Roanoke Regional
LGA
LaGuardia
$352 Roundtrip, found 1 day ago
$352
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jul 9 from Roanoke Regional to LaGuardia, returning Tue, Jul 22, priced at $352 found 1 day ago
Mon, Sep 29 - Sun, Oct 5
ROA
Roanoke Regional
LGA
LaGuardia
$355 Roundtrip, found 2 days ago
$355
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Sep 29 from Roanoke Regional to LaGuardia, returning Sun, Oct 5, priced at $355 found 2 days ago
Fri, Jul 11 - Tue, Jul 15
ROA
Roanoke Regional
LGA
LaGuardia
$357 Roundtrip, found 1 day ago
$357
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Jul 11 from Roanoke Regional to LaGuardia, returning Tue, Jul 15, priced at $357 found 1 day ago

Frequently asked questions

What route does flight number DL5321 take?
You’ll arrive into Roger Milliken Field from Detroit, MI Airport (DTW-Detroit Metropolitan Wayne County) if you’ve booked a ticket on flight number DL5321. You’ll be in the sky for 1 hour and 41 minutes during this journey. What’s more, the service conveniently travels non-stop.
What terminal does DL5321 fly out of?
Travelers with a booking on flight number DL5321 from Metro Airport to Greenville-Spartanburg Intl. Airport (GSP) usually depart from Terminal EM.
What kind of plane is on flight number DL5321?
Get set to hop on board a Bombardier CRJ900 if you’ve booked a seat on flight DL5321. The majority of flights from DTW to Greenville, SC Airport (GSP-Greenville-Spartanburg Intl.) use this aircraft model.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your DL5321 flight with Travelocity, please visit our Customer Service Portal.