American Airlines Flight 5221 Deals & Information (2026/2027)

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American Airlines Flight 5221 Route Deals From $241

The cheapest prices found with in the last 7 days for return flights were $383 and $241 for one-way flights to Dane County Regional for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, May 20 - Wed, May 27
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$383 Roundtrip, found 1 day ago
$383
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 20 from Ronald Reagan Washington National to Dane County Regional, returning Wed, May 27, priced at $383 found 1 day ago
Wed, May 20 - Wed, May 27
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$388 Roundtrip, found 1 day ago
$388
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 20 from Ronald Reagan Washington National to Dane County Regional, returning Wed, May 27, priced at $388 found 1 day ago
Wed, May 20 - Wed, May 27
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$393 Roundtrip, found 1 day ago
$393
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 20 from Ronald Reagan Washington National to Dane County Regional, returning Wed, May 27, priced at $393 found 1 day ago
Wed, May 20 - Wed, May 27
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$403 Roundtrip, found 1 day ago
$403
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 20 from Ronald Reagan Washington National to Dane County Regional, returning Wed, May 27, priced at $403 found 1 day ago
Wed, May 20 - Wed, May 27
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$416 Roundtrip, found 1 day ago
$416
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 20 from Ronald Reagan Washington National to Dane County Regional, returning Wed, May 27, priced at $416 found 1 day ago
Wed, May 6 - Sat, May 9
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$420 Roundtrip, found 18 hours ago
$420
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Wed, May 6 from Ronald Reagan Washington National to Dane County Regional, returning Sat, May 9, priced at $420 found 18 hours ago
Tue, Apr 21 - Sat, Aug 15
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$421 Roundtrip, found 1 day ago
$421
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Apr 21 from Ronald Reagan Washington National to Dane County Regional, returning Sat, Aug 15, priced at $421 found 1 day ago
Wed, May 20 - Wed, May 27
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$430 Roundtrip, found 1 day ago
$430
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 20 from Ronald Reagan Washington National to Dane County Regional, returning Wed, May 27, priced at $430 found 1 day ago
Wed, May 6 - Sat, May 9
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$430 Roundtrip, found 18 hours ago
$430
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Wed, May 6 from Ronald Reagan Washington National to Dane County Regional, returning Sat, May 9, priced at $430 found 18 hours ago
Wed, May 20 - Thu, May 28
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$432 Roundtrip, found 1 day ago
$432
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, May 20 from Ronald Reagan Washington National to Dane County Regional, returning Thu, May 28, priced at $432 found 1 day ago

Frequently asked questions

What route does flight number AA5221 take?
AA5221 is used on multiple routes. More commonly, AA5221 flies straight from Daytona Beach, FL Airport (DAB-Daytona Beach Intl.) to Charlotte, NC Airport (CLT-Charlotte-Douglas Intl.). If you've booked a seat on this route, you'll be up above the clouds for around 1 hour and 48 minutes.
How often is AA5221 on time?
If you're traveling with American Airlines flight number AA5221 from DAB to Charlotte, NC Airport (CLT-Charlotte-Douglas Intl.), it's a relief knowing that their planes run according to schedule 92% of the time. In the rare event that a flight is running behind schedule, it should only be delayed by around 10 minutes. Thanks to this airline's top standards, this flight has a 3.9-star rating.
What kind of plane is on flight number AA5221?
If you have a seat on flight AA5221 from Daytona Beach Intl. Airport (DAB) to Charlotte Airport, you'll likely be aboard the Bombardier CRJ900. This flight number serves a number of routes, but this is the most common one.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA5221 flight with Travelocity, please visit our Customer Service Portal.