American Airlines Flight 5221 Deals & Information (2025/2026)

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American Airlines Flight 5221 Route Deals From $130

The cheapest prices found with in the last 7 days for return flights were $273 and $130 for one-way flights to Dane County Regional for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Nov 22 - Tue, Dec 2
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$273 Roundtrip, found 6 days ago
$273
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Nov 22 from Ronald Reagan Washington National to Dane County Regional, returning Tue, Dec 2, priced at $273 found 6 days ago
Sat, Nov 22 - Tue, Dec 2
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$274 Roundtrip, found 6 days ago
$274
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Nov 22 from Ronald Reagan Washington National to Dane County Regional, returning Tue, Dec 2, priced at $274 found 6 days ago
Sat, Nov 22 - Tue, Dec 2
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$284 Roundtrip, found 6 days ago
$284
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Nov 22 from Ronald Reagan Washington National to Dane County Regional, returning Tue, Dec 2, priced at $284 found 6 days ago
Sat, Nov 22 - Tue, Dec 2
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$309 Roundtrip, found 6 days ago
$309
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Nov 22 from Ronald Reagan Washington National to Dane County Regional, returning Tue, Dec 2, priced at $309 found 6 days ago
Sat, Nov 22 - Tue, Dec 2
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$314 Roundtrip, found 6 days ago
$314
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Nov 22 from Ronald Reagan Washington National to Dane County Regional, returning Tue, Dec 2, priced at $314 found 6 days ago
Sat, Nov 22 - Tue, Dec 2
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$323 Roundtrip, found 6 days ago
$323
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Nov 22 from Ronald Reagan Washington National to Dane County Regional, returning Tue, Dec 2, priced at $323 found 6 days ago
Wed, Nov 19 - Tue, Nov 25
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$335 Roundtrip, found 3 days ago
$335
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Nov 19 from Ronald Reagan Washington National to Dane County Regional, returning Tue, Nov 25, priced at $335 found 3 days ago
Sun, Dec 21 - Sat, Jan 3
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$383 Roundtrip, found 9 hours ago
$383
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sun, Dec 21 from Ronald Reagan Washington National to Dane County Regional, returning Sat, Jan 3, priced at $383 found 9 hours ago
Fri, Nov 28 - Sat, Nov 29
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$389 Roundtrip, found 6 hours ago
$389
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Nov 28 from Ronald Reagan Washington National to Dane County Regional, returning Sat, Nov 29, priced at $389 found 6 hours ago
Fri, Nov 28 - Sat, Nov 29
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$399 Roundtrip, found 6 hours ago
$399
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Nov 28 from Ronald Reagan Washington National to Dane County Regional, returning Sat, Nov 29, priced at $399 found 6 hours ago

Frequently asked questions

What route does flight number AA5221 take?
AA5221 is used on multiple routes. More commonly, AA5221 flies straight from Daytona Beach, FL Airport (DAB-Daytona Beach Intl.) to Charlotte, NC Airport (CLT-Charlotte-Douglas Intl.). If you've booked a seat on this route, you'll be up above the clouds for around 1 hour and 48 minutes.
How often is AA5221 on time?
If you're traveling with American Airlines flight number AA5221 from DAB to Charlotte, NC Airport (CLT-Charlotte-Douglas Intl.), it's a relief knowing that their planes run according to schedule 92% of the time. In the rare event that a flight is running behind schedule, it should only be delayed by around 10 minutes. Thanks to this airline's top standards, this flight has a 3.9-star rating.
What kind of plane is on flight number AA5221?
If you have a seat on flight AA5221 from Daytona Beach Intl. Airport (DAB) to Charlotte Airport, you'll likely be aboard the Bombardier CRJ900. This flight number serves a number of routes, but this is the most common one.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA5221 flight with Travelocity, please visit our Customer Service Portal.