American Airlines Flight 5221 Deals & Information (2025/2026)

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American Airlines Flight 5221 Route Deals From $183

The cheapest prices found with in the last 7 days for return flights were $307 and $183 for one-way flights to Dane County Regional for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Jan 15 - Tue, Jan 20
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$307 Roundtrip, found 1 day ago
$307
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Jan 15 from Ronald Reagan Washington National to Dane County Regional, returning Tue, Jan 20, priced at $307 found 1 day ago
Fri, Apr 24 - Sun, Apr 26
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$308 Roundtrip, found 5 days ago
$308
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Apr 24 from Ronald Reagan Washington National to Dane County Regional, returning Sun, Apr 26, priced at $308 found 5 days ago
Wed, Jan 14 - Sat, Jan 17
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$320 Roundtrip, found 20 hours ago
$320
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Jan 14 from Ronald Reagan Washington National to Dane County Regional, returning Sat, Jan 17, priced at $320 found 20 hours ago
Wed, Jan 14 - Sat, Jan 17
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$326 Roundtrip, found 20 hours ago
$326
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Jan 14 from Ronald Reagan Washington National to Dane County Regional, returning Sat, Jan 17, priced at $326 found 20 hours ago
Wed, Jan 14 - Sat, Jan 17
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$330 Roundtrip, found 20 hours ago
$330
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Jan 14 from Ronald Reagan Washington National to Dane County Regional, returning Sat, Jan 17, priced at $330 found 20 hours ago
Thu, Jan 1 - Mon, Jan 5
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$350 Roundtrip, found 6 days ago
$350
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Jan 1 from Ronald Reagan Washington National to Dane County Regional, returning Mon, Jan 5, priced at $350 found 6 days ago
Fri, Apr 24 - Sat, Apr 25
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$359 Roundtrip, found 5 days ago
$359
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Apr 24 from Ronald Reagan Washington National to Dane County Regional, returning Sat, Apr 25, priced at $359 found 5 days ago
Thu, Feb 5 - Sun, Feb 8
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$360 Roundtrip, found 3 days ago
$360
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Feb 5 from Ronald Reagan Washington National to Dane County Regional, returning Sun, Feb 8, priced at $360 found 3 days ago
Wed, Jan 14 - Sat, Jan 17
DCA
Ronald Reagan Washington National
MSN
Dane County Regional
$363 Roundtrip, found 20 hours ago
$363
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Jan 14 from Ronald Reagan Washington National to Dane County Regional, returning Sat, Jan 17, priced at $363 found 20 hours ago

Frequently asked questions

What route does flight number AA5221 take?
AA5221 is used on multiple routes. More commonly, AA5221 flies straight from Daytona Beach, FL Airport (DAB-Daytona Beach Intl.) to Charlotte, NC Airport (CLT-Charlotte-Douglas Intl.). If you've booked a seat on this route, you'll be up above the clouds for around 1 hour and 48 minutes.
How often is AA5221 on time?
If you're traveling with American Airlines flight number AA5221 from DAB to Charlotte, NC Airport (CLT-Charlotte-Douglas Intl.), it's a relief knowing that their planes run according to schedule 92% of the time. In the rare event that a flight is running behind schedule, it should only be delayed by around 10 minutes. Thanks to this airline's top standards, this flight has a 3.9-star rating.
What kind of plane is on flight number AA5221?
If you have a seat on flight AA5221 from Daytona Beach Intl. Airport (DAB) to Charlotte Airport, you'll likely be aboard the Bombardier CRJ900. This flight number serves a number of routes, but this is the most common one.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA5221 flight with Travelocity, please visit our Customer Service Portal.