American Airlines Flight 4578 Deals & Information (2026/2027)

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American Airlines Flight 4578 Route Deals From $211

The cheapest prices found with in the last 7 days for return flights were $339 and $211 for one-way flights to LaGuardia for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, May 2 - Mon, Aug 9
GSP
Greenville-Spartanburg Intl.
LGA
LaGuardia
$339 Roundtrip, found 4 days ago
$339
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sun, May 2 from Greenville-Spartanburg Intl. to LaGuardia, returning Mon, Aug 9, priced at $339 found 4 days ago
Sun, May 2 - Mon, Aug 9
GSP
Greenville-Spartanburg Intl.
LGA
LaGuardia
$349 Roundtrip, found 4 days ago
$349
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sun, May 2 from Greenville-Spartanburg Intl. to LaGuardia, returning Mon, Aug 9, priced at $349 found 4 days ago
Tue, Nov 10 - Sat, Nov 14
GSP
Greenville-Spartanburg Intl.
LGA
LaGuardia
$353 Roundtrip, found 5 days ago
$353
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Nov 10 from Greenville-Spartanburg Intl. to LaGuardia, returning Sat, Nov 14, priced at $353 found 5 days ago
Mon, Nov 16 - Wed, Nov 18
GSP
Greenville-Spartanburg Intl.
LGA
LaGuardia
$364 Roundtrip, found 3 days ago
$364
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Nov 16 from Greenville-Spartanburg Intl. to LaGuardia, returning Wed, Nov 18, priced at $364 found 3 days ago
Tue, Nov 10 - Sat, Nov 14
GSP
Greenville-Spartanburg Intl.
LGA
LaGuardia
$380 Roundtrip, found 5 days ago
$380
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Nov 10 from Greenville-Spartanburg Intl. to LaGuardia, returning Sat, Nov 14, priced at $380 found 5 days ago
Fri, Dec 11 - Mon, Dec 14
GSP
Greenville-Spartanburg Intl.
LGA
LaGuardia
$386 Roundtrip, found 3 days ago
$386
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Dec 11 from Greenville-Spartanburg Intl. to LaGuardia, returning Mon, Dec 14, priced at $386 found 3 days ago
Sun, May 2 - Mon, Aug 9
GSP
Greenville-Spartanburg Intl.
LGA
LaGuardia
$389 Roundtrip, found 4 days ago
$389
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sun, May 2 from Greenville-Spartanburg Intl. to LaGuardia, returning Mon, Aug 9, priced at $389 found 4 days ago
Wed, Dec 23 - Tue, Dec 29
GSP
Greenville-Spartanburg Intl.
LGA
LaGuardia
$390 Roundtrip, found 1 day ago
$390
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Dec 23 from Greenville-Spartanburg Intl. to LaGuardia, returning Tue, Dec 29, priced at $390 found 1 day ago
Sat, Nov 14 - Mon, Nov 16
GSP
Greenville-Spartanburg Intl.
LGA
LaGuardia
$396 Roundtrip, found 3 days ago
$396
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Nov 14 from Greenville-Spartanburg Intl. to LaGuardia, returning Mon, Nov 16, priced at $396 found 3 days ago
Sat, Dec 12 - Mon, Dec 14
GSP
Greenville-Spartanburg Intl.
LGA
LaGuardia
$397 Roundtrip, found 18 hours ago
$397
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Sat, Dec 12 from Greenville-Spartanburg Intl. to LaGuardia, returning Mon, Dec 14, priced at $397 found 18 hours ago
Sat, Nov 14 - Mon, Nov 16
GSP
Greenville-Spartanburg Intl.
LGA
LaGuardia
$398 Roundtrip, found 3 days ago
$398
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Nov 14 from Greenville-Spartanburg Intl. to LaGuardia, returning Mon, Nov 16, priced at $398 found 3 days ago
Fri, Nov 20 - Sun, Nov 22
GSP
Greenville-Spartanburg Intl.
LGA
LaGuardia
$407 Roundtrip, found 5 hours ago
$407
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Fri, Nov 20 from Greenville-Spartanburg Intl. to LaGuardia, returning Sun, Nov 22, priced at $407 found 5 hours ago
Sat, Dec 12 - Mon, Dec 14
GSP
Greenville-Spartanburg Intl.
LGA
LaGuardia
$407 Roundtrip, found 18 hours ago
$407
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Sat, Dec 12 from Greenville-Spartanburg Intl. to LaGuardia, returning Mon, Dec 14, priced at $407 found 18 hours ago
Thu, Dec 24 - Tue, Dec 29
GSP
Greenville-Spartanburg Intl.
LGA
LaGuardia
$409 Roundtrip, found 18 hours ago
$409
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Thu, Dec 24 from Greenville-Spartanburg Intl. to LaGuardia, returning Tue, Dec 29, priced at $409 found 18 hours ago

Frequently asked questions

What route does flight number AA4578 take?
AA4578 is used on a number of routes. Mostly, AA4578 flies directly from PHL to PBI. If you've booked a seat on this route, you'll be traveling for about 2 hours and 54 minutes.
What kind of plane is on flight number AA4578?
It's likely you'll be aboard the Embraer 175 if you're going from PHL to PBI, one route used for flight AA4578.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4578 flight with Travelocity, please visit our Customer Service Portal.