American Airlines Flight 4540 Deals & Information (2025/2026)

Wander Wisely with exceptional service, 24/7 supportOpens in a new window

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

American Airlines Flight 4540 Route Deals From $178

The cheapest prices found with in the last 7 days for return flights were $249 and $178 for one-way flights to Key West Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Oct 22 - Mon, Oct 27
DCA
Ronald Reagan Washington National
EYW
Key West Intl.
$249 Roundtrip, found 8 hours ago
$249
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Oct 22 from Ronald Reagan Washington National to Key West Intl., returning Mon, Oct 27, priced at $249 found 8 hours ago
Sun, Sep 7 - Wed, Sep 17
DCA
Ronald Reagan Washington National
EYW
Key West Intl.
$253 Roundtrip, found 2 days ago
$253
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Sep 7 from Ronald Reagan Washington National to Key West Intl., returning Wed, Sep 17, priced at $253 found 2 days ago
Thu, Nov 27 - Tue, Dec 2
DCA
Ronald Reagan Washington National
EYW
Key West Intl.
$264 Roundtrip, found 16 hours ago
$264
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Thu, Nov 27 from Ronald Reagan Washington National to Key West Intl., returning Tue, Dec 2, priced at $264 found 16 hours ago
Sat, Aug 23 - Sat, Aug 30
DCA
Ronald Reagan Washington National
EYW
Key West Intl.
$269 Roundtrip, found 3 days ago
$269
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Aug 23 from Ronald Reagan Washington National to Key West Intl., returning Sat, Aug 30, priced at $269 found 3 days ago
Wed, Nov 5 - Sat, Nov 8
DCA
Ronald Reagan Washington National
EYW
Key West Intl.
$279 Roundtrip, found 19 hours ago
$279
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Wed, Nov 5 from Ronald Reagan Washington National to Key West Intl., returning Sat, Nov 8, priced at $279 found 19 hours ago
Tue, Oct 21 - Fri, Oct 31
DCA
Ronald Reagan Washington National
EYW
Key West Intl.
$288 Roundtrip, found 2 days ago
$288
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Oct 21 from Ronald Reagan Washington National to Key West Intl., returning Fri, Oct 31, priced at $288 found 2 days ago
Wed, Oct 22 - Mon, Oct 27
DCA
Ronald Reagan Washington National
EYW
Key West Intl.
$299 Roundtrip, found 8 hours ago
$299
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Oct 22 from Ronald Reagan Washington National to Key West Intl., returning Mon, Oct 27, priced at $299 found 8 hours ago
Sat, Aug 23 - Sat, Aug 30
DCA
Ronald Reagan Washington National
EYW
Key West Intl.
$304 Roundtrip, found 3 days ago
$304
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Aug 23 from Ronald Reagan Washington National to Key West Intl., returning Sat, Aug 30, priced at $304 found 3 days ago
Sun, Sep 7 - Wed, Sep 17
DCA
Ronald Reagan Washington National
EYW
Key West Intl.
$313 Roundtrip, found 2 days ago
$313
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Sep 7 from Ronald Reagan Washington National to Key West Intl., returning Wed, Sep 17, priced at $313 found 2 days ago
Thu, Sep 4 - Thu, Sep 11
DCA
Ronald Reagan Washington National
EYW
Key West Intl.
$317 Roundtrip, found 5 days ago
$317
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Sep 4 from Ronald Reagan Washington National to Key West Intl., returning Thu, Sep 11, priced at $317 found 5 days ago

Frequently asked questions

What route does flight number AA4540 take?
AA4540 flies straight from CLE to PHL in 1 hour and 33 minutes. It can sometimes take other routes though, some of which may be multi-stop journeys. Keep this in mind when locking in your airfare to avoid any confusion.
What kind of plane is on flight number AA4540?
AA4540 is a flight number that's used on many different routes. If you're traveling on the busiest route, Cleveland Hopkins Intl. Airport to Philadelphia Intl. Airport (PHL), you'll likely be boarding an Embraer 175.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4540 flight with Travelocity, please visit our Customer Service Portal.